Výsledky vyhledávání - "John M Gardiner"

Akademický článek

Synthesis, characterization, thermokinetic analysis and biological application of novel allyl glucosamine based glycopolymers

Autor: Yeliz Yıldırım, Fatma Telli, Erkan Kahraman, John M. Gardiner

Publikováno v: Designed Monomers and Polymers, Vol 26, Iss 1, Pp 117-131 (2023)

The synthesis of glycopolymers by copolymerising an allyl glucosamine (AG) monomer with co-monomers methyl methacrylate (MMA), acrylonitrile (AN) and 2-hydroxyethyl methacrylate (HEMA) was investigated via free-radical polymerisation of 2,2-azobisiso

Externí odkaz: https://doaj.org/article/ff039db5df1e4da8b44ac78354076db5

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Akademický článek

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Akademický článek

Synthesis, structural characterization, and computational study of (E)-N′-(3,4-dimethoxybenzylidene)furan-2-carbohydrazide

Autor: Ahmed M. Mkadmh, Rami Y. Morjan, James Raftery, Adel M. Awadallah, John M. Gardiner

Publikováno v: Arabian Journal of Chemistry, Vol 13, Iss 1, Pp 3571-3584 (2020)

An efficient synthesis of the new (E)-N′-(3,4-dimethoxybenzylidene)furan-2-carbohydrazide is described. Its molecular structural features have been characterized by FTIR, 1H NMR, 13C NMR and MS, then have been confirmed by single crystal X-ray diff

Externí odkaz: https://doaj.org/article/cc0b2c499bde433f8504cb282589439a

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Unexpected Diastereomer Formation and Interconversions in Cyclohexane-1,2-diacetal Derivatization of a Glucuronic Acid Thioglycoside

Autor: Fahad Ayesh Alharthi, Garrett T. Potter, Gordon C. Jayson, George F. S. Whitehead, Iñigo J. Vitórica-Yrezábal, John M. Gardiner

Publikováno v: Organic Letters. 25:2196-2200

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a8c1cf97551a32ae98f7992fb926b4b
https://doi.org/10.1021/acs.orglett.3c00255

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Akademický článek

Inversion dimers dominate the crystal packing in the structure of trimethyl citrate (trimethyl 2-hydroxypropane-1,2,3-tricarboxylate)

Autor: Rami Y. Morjan, Said M. El-Kurdi, Jannat N. Azarah, Neda A. Eleiwa, Omar S. Abu-Teim, Adel M. Awadallah, James Raftery, John M. Gardiner

Publikováno v: Acta Crystallographica Section E: Crystallographic Communications, Vol 74, Iss 9, Pp 1362-1365 (2018)

Trimethyl citrate, C9H14O7 (systematic name: trimethyl 2-hydroxypropane-1,2,3-tricarboxylate), 2, was prepared by the esterification of citric acid and methanol in the presence of thionyl chloride at 273 K. The bond lengths and angles in 2 compare cl

Externí odkaz: https://doaj.org/article/35880002a57d45478dfb347045f5d885

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Synthesis, docking and evaluation of novel fused pyrimidine compounds as possible lead compounds with antibacterial and antitumor activities

Autor: Rami Y. Morjan, Amany F. El-Hallaq, Jannat N. Azarah, Ihab M. Almasri, Mazen M. Alzaharna, Mariam R. Al-Reefi, Ian Beadham, Omar S. Abu-Teim, Abdelraouf A. Elmanama, Adel M. Awadallah, James Raftery, John M. Gardiner

Publikováno v: Journal of Molecular Structure. 1288:135754

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c0012f04a4f30eea9e440191da9902e
https://doi.org/10.1016/j.molstruc.2023.135754

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Akademický článek

Modular Synthesis of Heparin-Related Tetra-, Hexa- and Octasaccharides with Differential O-6 Protections: Programming for Regiodefined 6-O-Modifications

Autor: Marek Baráth, Steen U. Hansen, Charlotte E. Dalton, Gordon C. Jayson, Gavin J. Miller, John M. Gardiner

Publikováno v: Molecules, Vol 20, Iss 4, Pp 6167-6180 (2015)

Heparin and heparan sulphate (H/HS) are important members of the glycosaminoglycan family of sugars that regulate a substantial number of biological processes. Such biological promiscuity is underpinned by hetereogeneity in their molecular structure.

Externí odkaz: https://doaj.org/article/1e16d2015b644657a226a97d08326947

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The crystal structure of methyl 3,5-diaminobenzoate, C8H10N2O2

Autor: John M. Gardiner, James Raftery, Ian G. Beadham, Jannat N. Azarah, Mohammed Y. Abu-Foul, Adel M. Awadallah, Rami Y. Morjan

Publikováno v: Zeitschrift für Kristallographie - New Crystal Structures. 238:109-110

C8H10N2O2, orthorhombic, Pbca (no. 61), a = 11.0571(2) Å, b = 8.1172(2) Å, c = 17.6080(4) Å, V = 1580.37(6) Å3, Z = 8, R gt (F) = 0.0324, wR ref (F 2) = 0.0872, T = 100(2) K.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa422110e3870a506a7942bef9f65f75
https://doi.org/10.1515/ncrs-2022-0485

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Synthesis and structure of d-glucuronolactone derived carboxamides

Autor: Saravanan Kandasamy, George F.S. Whitehead, Iñigo J. Vitórica-Yrezábal, John M. Gardiner

Publikováno v: Carbohydrate Research. 524:108744

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::321375887ddc5621ff84d056030e6357
https://doi.org/10.1016/j.carres.2023.108744

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Akademický článek

Synthetic Site-Selectively Mono-6-O-Sulfated Heparan Sulfate Dodecasaccharide Shows Anti-Angiogenic Properties In Vitro and Sensitizes Tumors to Cisplatin In Vivo.

Autor: Egle Avizienyte, Claire L Cole, Graham Rushton, Gavin J Miller, Antonella Bugatti, Marco Presta, John M Gardiner, Gordon C Jayson

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0159739 (2016)

Heparan sulphate (HS), a ubiquitously expressed glycosaminoglycan (GAG), regulates multiple cellular functions by mediating interactions between numerous growth factors and their cell surface cognate receptors. However, the structural specificity of

Externí odkaz: https://doaj.org/article/44a851b5c5644841994c9c35f621831b

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