Zobrazeno 1 - 10
of 26
pro vyhledávání: '"John M Beals"'
Autor:
Alexei Kharitonenkov, John M Beals, Radmila Micanovic, Beth A Strifler, Radhakrishnan Rathnachalam, Victor J Wroblewski, Shun Li, Anja Koester, Amy M Ford, Tamer Coskun, James D Dunbar, Christine C Cheng, Christopher C Frye, Thomas F Bumol, David E Moller
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58575 (2013)
Fibroblast growth factor 21 is a novel hormonal regulator with the potential to treat a broad variety of metabolic abnormalities, such as type 2 diabetes, obesity, hepatic steatosis, and cardiovascular disease. Human recombinant wild type FGF21 (FGF2
Externí odkaz:
https://doaj.org/article/5847a90134ee450d8853ad80dc8fbeb7
Autor:
Anjul Khadria, Chad D. Paavola, Yang Zhang, Samuel P. X. Davis, Patrick F. Grealish, Konstantin Maslov, Junhui Shi, John M. Beals, Sunday S. Oladipupo, Lihong V. Wang
Publikováno v:
Advanced Science, Vol 9, Iss 28, Pp n/a-n/a (2022)
Abstract Long‐duration in vivo simultaneous imaging of multiple anatomical structures is useful for understanding physiological aspects of diseases, informative for molecular optimization in preclinical models, and has potential applications in sur
Externí odkaz:
https://doaj.org/article/498ead5453b94d83a6350b74c3161580
Autor:
Julie S, Moyers, Ryan J, Hansen, Jonathan W, Day, Craig D, Dickinson, Chen, Zhang, Xiaoping, Ruan, Liyun, Ding, Robin M, Brown, Hana E, Baker, John M, Beals
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:346-355
The benefit of once-weekly basal insulin is less frequent dosing, which has the potential to reduce the barrier to injection therapy and impact patient activation, adherence and compliance, quality of life, and outcomes. Basal Insulin Fc (BIF, LY3209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c435ab7265da35669d2b5357f9bdda
https://doi.org/10.1124/jpet.122.001105
https://doi.org/10.1124/jpet.122.001105
Autor:
Tim Heise, Jenny Chien, John M. Beals, Charles Benson, Oliver Klein, Julie S. Moyers, Axel Haupt, Edward John Pratt
Publikováno v:
Diabetes, obesitymetabolism.
Basal Insulin Fc (BIF; LY3209590), a fusion protein combining a novel single-chain insulin variant together with human IgG2 Fc domain, is designed for once-weekly administration. First-in-human studies assessed safety, tolerability, pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797c3047c9d97537b76f51bb6c5d3154
https://pubmed.ncbi.nlm.nih.gov/36541037
https://pubmed.ncbi.nlm.nih.gov/36541037
Autor:
null Tim Heise, null Jenny Chien, null John M. Beals, null Charles Benson, null Oliver Klein, null Julie S. Moyers, null Axel Haupt, null Edward John Pratt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c378b5a771041e487c1108c089668ffd
https://doi.org/10.1111/dom.14956/v3/response1
https://doi.org/10.1111/dom.14956/v3/response1
Autor:
Anjul Khadria, Chad D. Paavola, Konstantin Maslov, Patricia L. Brown-Augsburger, Patrick F. Grealish, Emmanuel Lozano, Ross L. Blankenship, Rui Cao, Junhui Shi, John M. Beals, Sunday S Oladipupo, Lihong V. Wang
Over 100 monoclonal antibodies have been approved by the FDA for clinical use; however, a paucity of knowledge exists regarding the injection site behavior of these formulated therapeutics, i.e., the effect of antibody and formulation on the tissue a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a84a060b67bf2dc067a9d8eada60bc4
https://doi.org/10.1101/2022.09.29.509334
https://doi.org/10.1101/2022.09.29.509334
Autor:
Anjul Khadria, Chad D. Paavola, Konstantin Maslov, Francisco A. Valenzuela, Andrea E. Sperry, Amy L. Cox, Rui Cao, Junhui Shi, Patricia L. Brown-Augsburger, Emmanuel Lozano, Ross L. Blankenship, Ranajoy Majumdar, Scott A. Bradley, John M. Beals, Sunday S. Oladipupo, Lihong V. Wang
ObjectiveUltra-rapid insulin formulations control postprandial hyperglycemia; however, inadequate understanding of injection site absorption mechanisms is limiting further advancement. We used photoacoustic imaging to investigate the injection site d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2654373684af18f6ec1a666af18cced
https://resolver.caltech.edu/CaltechAUTHORS:20220315-626283000
https://resolver.caltech.edu/CaltechAUTHORS:20220315-626283000
Autor:
John M. Beals, Michael R. DeFelippis, Chad D. Paavola, David P. Allen, Ashish Garg, D. Bruce Baldwin
Publikováno v:
Pharmaceutical Biotechnology ISBN: 9783030007096
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de412623b0efa9785f2b8fb215f9230f
https://doi.org/10.1007/978-3-030-00710-2_18
https://doi.org/10.1007/978-3-030-00710-2_18