Zobrazeno 1 - 10
of 84
pro vyhledávání: '"John M Baer"'
Autor:
Melissa A. Meyer, John M. Baer, Brett L. Knolhoff, Timothy M. Nywening, Roheena Z. Panni, Xinming Su, Katherine N. Weilbaecher, William G. Hawkins, Cynthia Ma, Ryan C. Fields, David C. Linehan, Grant A. Challen, Roberta Faccio, Rebecca L. Aft, David G. DeNardo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Tumors escape the immune system through many mechanisms. Here the authors show that certain tumors inhibit anti-tumor immunity by stopping the production of conventional dendritic cells (cDCs) in the bone marrow, therefore depleting the pool of cDCs
Externí odkaz:
https://doaj.org/article/8ebabe15d49943d1834201842048ea26
Autor:
C. Alston. James, John M. Baer, Chong Zuo, Usman Y. Panni, Brett L. Knolhoff, Graham D. Hogg, Natalie L. Kingston, Liang-I Kang, Varintra E. Lander, Jingqin Luo, Yu Tao, Mark A. Watson, Rebecca Aft, Ryan C. Fields, William G. Hawkins, David G. DeNardo
Publikováno v:
Cancer Immunology Research.
Intratumoral T-cell dysfunction is a hallmark of pancreatic tumors, and efforts to improve dendritic cell (DC)-mediated T-cell activation may be critical in treating these immune therapy unresponsive tumors. Recent evidence indicates that mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0093927b38674f57bfb49aa070bc6253
https://doi.org/10.1158/2326-6066.cir-21-0946
https://doi.org/10.1158/2326-6066.cir-21-0946
Autor:
Usman Y. Panni, Michael Y. Chen, Felicia Zhang, Darren R. Cullinan, Lijin Li, C. Alston James, Xiuli Zhang, S. Rogers, A. Alarcon, John M. Baer, Daoxiang Zhang, Feng Gao, Christopher A. Miller, Qingqing Gong, Kian-Huat Lim, David G. DeNardo, S. Peter Goedegebuure, William E. Gillanders, William G. Hawkins
Publikováno v:
Cancer Immunology, Immunotherapy.
Neoantigen burden and CD8 T cell infiltrate are associated with clinical outcome in pancreatic ductal adenocarcinoma (PDAC). A shortcoming of many genetic models of PDAC is the lack of neoantigen burden and limited T cell infiltrate. The goal of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92edf9f6b271822fc53c075b57b0d503
https://doi.org/10.1007/s00262-023-03463-x
https://doi.org/10.1007/s00262-023-03463-x
Autor:
Xiuting Liu, Graham D. Hogg, Chong Zuo, Nicholas C. Borcherding, John M. Baer, Varintra E. Lander, Liang-I Kang, Brett L. Knolhoff, Faiz Ahmad, Robin E. Osterhout, Anna V. Galkin, Jean-Marie Bruey, Laura L. Carter, Cedric Mpoy, Kiran R. Vij, Ryan C. Fields, Julie K. Schwarz, Haeseong Park, Vineet Gupta, David G. DeNardo
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff6110ed034245fb490678109de1311
https://doi.org/10.1016/j.ccell.2023.04.018
https://doi.org/10.1016/j.ccell.2023.04.018
Autor:
David G. DeNardo, Hyun Kim, Julie K. Schwarz, Buck E. Rogers, Michael Zahner, Jalen Scott, Cedric Mpoy, Daniel P. Lander, Nicholas C. Borcherding, Chong Zuo, John M. Baer, Savannah J. Bogner, Brett L. Knolhoff, Liang-I Kang, Xiuting Liu, Graham D. Hogg, John M. Herndon, Natalie L. Kingston, Jad I. Belle, Varintra E. Lander
The effects of radiotherapy (RT) on tumor immunity in pancreatic ductal adenocarcinoma (PDAC) are not well understood. To better understand if RT can prime antigen-specific T-cell responses, we analyzed human PDAC tissues and mouse models. In both se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f7001041d74584b705d27bbfb384c1
https://doi.org/10.1158/2159-8290.c.6549747
https://doi.org/10.1158/2159-8290.c.6549747
Autor:
David G. DeNardo, Hyun Kim, Julie K. Schwarz, Buck E. Rogers, Michael Zahner, Jalen Scott, Cedric Mpoy, Daniel P. Lander, Nicholas C. Borcherding, Chong Zuo, John M. Baer, Savannah J. Bogner, Brett L. Knolhoff, Liang-I Kang, Xiuting Liu, Graham D. Hogg, John M. Herndon, Natalie L. Kingston, Jad I. Belle, Varintra E. Lander
Supplementary Table from Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79ed75015c59cd30d2021db1b9d2ece
https://doi.org/10.1158/2159-8290.22541799
https://doi.org/10.1158/2159-8290.22541799
Autor:
David G. DeNardo, Hyun Kim, Julie K. Schwarz, Buck E. Rogers, Michael Zahner, Jalen Scott, Cedric Mpoy, Daniel P. Lander, Nicholas C. Borcherding, Chong Zuo, John M. Baer, Savannah J. Bogner, Brett L. Knolhoff, Liang-I Kang, Xiuting Liu, Graham D. Hogg, John M. Herndon, Natalie L. Kingston, Jad I. Belle, Varintra E. Lander
Supplementary Figure from Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f80b39bd397158d0a497c9bb3e7dd92
https://doi.org/10.1158/2159-8290.22541817.v1
https://doi.org/10.1158/2159-8290.22541817.v1
Autor:
Chong Zuo, John M. Baer, Brett L. Knolhoff, Jad I. Belle, Xiuting Liu, Angela Alarcon De La Lastra, Christina Fu, Graham D. Hogg, Natalie L. Kingston, Marcus A. Breden, Paarth B. Dodhiawala, Daniel Cui Zhou, Varintra E. Lander, C. Alston James, Li Ding, Kian-Huat Lim, Ryan C. Fields, William G. Hawkins, Jason D. Weber, Guoyan Zhao, David G. DeNardo
Publikováno v:
Journal of Experimental Medicine. 220
Tumor-associated macrophages (TAMs) are abundant in pancreatic ductal adenocarcinomas (PDACs). While TAMs are known to proliferate in cancer tissues, the impact of this on macrophage phenotype and disease progression is poorly understood. We showed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::244de5f36f2ee868b3284ce1cdf23ed6
https://doi.org/10.1084/jem.20212062
https://doi.org/10.1084/jem.20212062
Autor:
Varintra E. Lander, Jad I. Belle, Natalie L. Kingston, John M. Herndon, Graham D. Hogg, Xiuting Liu, Liang-I Kang, Brett L. Knolhoff, Savannah J. Bogner, John M. Baer, Chong Zuo, Nicholas C. Borcherding, Daniel P. Lander, Cedric Mpoy, Jalen Scott, Michael Zahner, Buck E. Rogers, Julie K. Schwarz, Hyun Kim, David G. DeNardo
Publikováno v:
Cancer Discov
The effects of radiotherapy (RT) on tumor immunity in pancreatic ductal adenocarcinoma (PDAC) are not well understood. To better understand if RT can prime antigen-specific T-cell responses, we analyzed human PDAC tissues and mouse models. In both se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b84525687b295f67bf75f77dac77d1
https://europepmc.org/articles/PMC9722639/
https://europepmc.org/articles/PMC9722639/
Autor:
Simone Brioschi, Julia A. Belk, Vincent Peng, Martina Molgora, Patrick Fernandes Rodrigues, Khai M. Nguyen, Shoutang Wang, Siling Du, Wei-Le Wang, Gary E. Grajales-Reyes, Jennifer M. Ponce, Carla M. Yuede, Qingyun Li, John M. Baer, David G. DeNardo, Susan Gilfillan, Marina Cella, Ansuman T. Satpathy, Marco Colonna
Publikováno v:
Immunity. 56:1027-1045.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7cb105939c763b25d6363d01849d88e
https://doi.org/10.1016/j.immuni.2023.01.028
https://doi.org/10.1016/j.immuni.2023.01.028