Zobrazeno 1 - 10
of 57
pro vyhledávání: '"John M, Herndon"'
Autor:
Foluso O. Ademuyiwa, Feng Gao, Cherease R. Street, Ina Chen, Donald W. Northfelt, Robert Wesolowski, Mili Arora, Adam Brufsky, E. Claire Dees, Cesar A. Santa-Maria, Roisin M. Connolly, Jeremy Force, Alvaro Moreno-Aspitia, John M. Herndon, Madelyn Carmody, Sherri R. Davies, Sarah Larson, Kathleen L. Pfaff, Stephanie M. Jones, Jason L. Weirather, Anita Giobbie-Hurder, Scott J. Rodig, Zheng Liu, Ian S. Hagemann, Elad Sharon, William E. Gillanders
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Atezolizumab with chemotherapy has shown improved progression-free and overall survival in patients with metastatic PD-L1 positive triple negative breast cancer (TNBC). Atezolizumab with anthracycline- and taxane-based neoadjuvant chemothera
Externí odkaz:
https://doaj.org/article/d2b06f8f41a040519a09fe040f35b01e
Autor:
Narendra V. Sankpal, Taylor C. Brown, Timothy P. Fleming, John M. Herndon, Anusha A. Amaravati, Allison N. Loynd, William E. Gillanders
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background EpCAM (Epithelial cell adhesion molecule) is often dysregulated in epithelial cancers. Prior studies implicate EpCAM in the regulation of oncogenic signaling pathways and epithelial-to-mesenchymal transition. It was recently demon
Externí odkaz:
https://doaj.org/article/38b6284507a6410392762012b6929067
Autor:
Lijin Li, Xiuli Zhang, Xiaoli Wang, Samuel W. Kim, John M. Herndon, Michelle K. Becker-Hapak, Beatriz M. Carreno, Nancy B. Myers, Mark A. Sturmoski, Michael D. McLellan, Christopher A. Miller, Tanner M. Johanns, Benjamin R. Tan, Gavin P. Dunn, Timothy P. Fleming, Ted H. Hansen, S. Peter Goedegebuure, William E. Gillanders
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. DNA vaccines can be rapidly and efficiently manufac
Externí odkaz:
https://doaj.org/article/031af79ff43e4bff85ce49e20a87cccb
Autor:
David G. DeNardo, Hyun Kim, Julie K. Schwarz, Buck E. Rogers, Michael Zahner, Jalen Scott, Cedric Mpoy, Daniel P. Lander, Nicholas C. Borcherding, Chong Zuo, John M. Baer, Savannah J. Bogner, Brett L. Knolhoff, Liang-I Kang, Xiuting Liu, Graham D. Hogg, John M. Herndon, Natalie L. Kingston, Jad I. Belle, Varintra E. Lander
The effects of radiotherapy (RT) on tumor immunity in pancreatic ductal adenocarcinoma (PDAC) are not well understood. To better understand if RT can prime antigen-specific T-cell responses, we analyzed human PDAC tissues and mouse models. In both se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f7001041d74584b705d27bbfb384c1
https://doi.org/10.1158/2159-8290.c.6549747
https://doi.org/10.1158/2159-8290.c.6549747
Autor:
David G. DeNardo, Hyun Kim, Julie K. Schwarz, Buck E. Rogers, Michael Zahner, Jalen Scott, Cedric Mpoy, Daniel P. Lander, Nicholas C. Borcherding, Chong Zuo, John M. Baer, Savannah J. Bogner, Brett L. Knolhoff, Liang-I Kang, Xiuting Liu, Graham D. Hogg, John M. Herndon, Natalie L. Kingston, Jad I. Belle, Varintra E. Lander
Supplementary Table from Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79ed75015c59cd30d2021db1b9d2ece
https://doi.org/10.1158/2159-8290.22541799
https://doi.org/10.1158/2159-8290.22541799
Autor:
David G. DeNardo, Hyun Kim, Julie K. Schwarz, Buck E. Rogers, Michael Zahner, Jalen Scott, Cedric Mpoy, Daniel P. Lander, Nicholas C. Borcherding, Chong Zuo, John M. Baer, Savannah J. Bogner, Brett L. Knolhoff, Liang-I Kang, Xiuting Liu, Graham D. Hogg, John M. Herndon, Natalie L. Kingston, Jad I. Belle, Varintra E. Lander
Supplementary Figure from Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f80b39bd397158d0a497c9bb3e7dd92
https://doi.org/10.1158/2159-8290.22541817.v1
https://doi.org/10.1158/2159-8290.22541817.v1
Autor:
William E. Gillanders, S. Peter Goedegebuure, Timothy P. Fleming, Ted Hansen, Elaine R. Mardis, Matthew J. Ellis, Chris A. Miller, Ian S. Hagemann, Mark Sturmoski, Tammi L. Vickery, Nancy Myers, Tina Primeau, Jeremy Hoog, Mike D. McLellan, Lijin Li, Savas D. Soysal, Allegra A. Petti, Shunqiang Li, John M. Herndon, Jasreet Hundal, Samuel Kim, Xiuli Zhang
Characterization of tier 1 mutations identified in WHIM37 through NSG.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b095b1efea13385ef9bd4fd734306f
https://doi.org/10.1158/2326-6066.22538777.v1
https://doi.org/10.1158/2326-6066.22538777.v1
Autor:
William E. Gillanders, S. Peter Goedegebuure, Timothy P. Fleming, Ted Hansen, Elaine R. Mardis, Matthew J. Ellis, Chris A. Miller, Ian S. Hagemann, Mark Sturmoski, Tammi L. Vickery, Nancy Myers, Tina Primeau, Jeremy Hoog, Mike D. McLellan, Lijin Li, Savas D. Soysal, Allegra A. Petti, Shunqiang Li, John M. Herndon, Jasreet Hundal, Samuel Kim, Xiuli Zhang
Characterization of tier 1 mutations identified in WHIM35 through NSG.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e589512e44c3b77224a8dbc1134db4
https://doi.org/10.1158/2326-6066.22538780.v1
https://doi.org/10.1158/2326-6066.22538780.v1
Autor:
William E. Gillanders, S. Peter Goedegebuure, Timothy P. Fleming, Ted Hansen, Elaine R. Mardis, Matthew J. Ellis, Chris A. Miller, Ian S. Hagemann, Mark Sturmoski, Tammi L. Vickery, Nancy Myers, Tina Primeau, Jeremy Hoog, Mike D. McLellan, Lijin Li, Savas D. Soysal, Allegra A. Petti, Shunqiang Li, John M. Herndon, Jasreet Hundal, Samuel Kim, Xiuli Zhang
Characterization of tier 1 mutations identified in WHIM30 through NSG.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a0621cea50385520354c448d6ddcb8
https://doi.org/10.1158/2326-6066.22538783.v1
https://doi.org/10.1158/2326-6066.22538783.v1
Autor:
William E. Gillanders, S. Peter Goedegebuure, Timothy P. Fleming, Ted Hansen, Elaine R. Mardis, Matthew J. Ellis, Chris A. Miller, Ian S. Hagemann, Mark Sturmoski, Tammi L. Vickery, Nancy Myers, Tina Primeau, Jeremy Hoog, Mike D. McLellan, Lijin Li, Savas D. Soysal, Allegra A. Petti, Shunqiang Li, John M. Herndon, Jasreet Hundal, Samuel Kim, Xiuli Zhang
Next-generation sequencing technologies have provided insights into the biology and mutational landscape of cancer. Here, we evaluate the relevance of cancer neoantigens in human breast cancers. Using patient-derived xenografts from three patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373d4a0c05b6ed776184bd81daf3d8a0
https://doi.org/10.1158/2326-6066.c.6548891
https://doi.org/10.1158/2326-6066.c.6548891