Zobrazeno 1 - 10
of 71
pro vyhledávání: '"John M, Dickenson"'
Publikováno v:
Biochemical Pharmacology. 164:289-298
Adequate invasion and complete remodelling of the maternal spiral arteries by the invading extravillous trophoblasts are the major determinants of a successful pregnancy. Increase in oxidative stress during pregnancy has been linked to the reduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e435a89fe25ed2c9d8c3396b1f9fbe3
https://doi.org/10.1016/j.bcp.2019.04.023
https://doi.org/10.1016/j.bcp.2019.04.023
Publikováno v:
Chemical research in toxicology. 33(9)
We have previously shown that phenyl saligenin phosphate (PSP), an organophosphorus compound which is classed as a weak inhibitor of acetylcholinesterase, triggered cytotoxicity in mitotic and differentiated H9c2 cardiomyoblasts. The aim of this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e8fc2a1edaa1d7fea4961f13d7c5b8
https://pubmed.ncbi.nlm.nih.gov/32786544
https://pubmed.ncbi.nlm.nih.gov/32786544
Publikováno v:
European Journal of Pharmacology. 820:113-129
NGF (nerve growth factor) and tissue transglutaminase (TG2) play important roles in neurite outgrowth and modulation of neuronal cell survival. In this study, we investigated the regulation of TG2 transamidase activity by NGF in retinoic acid-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbd87c35a44869aa1f83660d75bc019
https://doi.org/10.1016/j.ejphar.2017.12.023
https://doi.org/10.1016/j.ejphar.2017.12.023
Publikováno v:
European Journal of Pharmacology. 819:144-160
Pharmacologically-induced pre- and post-conditioning represent attractive therapeutic strategies to reduce ischaemia/reperfusion injury during cardiac surgery and following myocardial infarction. We have previously reported that transglutaminase 2 (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135c79035ff23421878fa6647a188a42
https://doi.org/10.1016/j.ejphar.2017.11.049
https://doi.org/10.1016/j.ejphar.2017.11.049
Autor:
David J. Boocock, Philip L.R. Bonner, Falguni S. Vyas, Alan J. Hargreaves, John M. Dickenson, Clare Coveney
Publikováno v:
Biochemical Pharmacology. 107:41-58
The regulation of tissue transglutaminase (TG2) activity by the GPCR family is poorly understood. In this study, we investigated the modulation of TG2 activity by the A1 adenosine receptor in cardiomyocyte-like H9c2 cells. H9c2 cells were lysed follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109985d18a3d15886cd46f27e9c1d14e
https://doi.org/10.1016/j.bcp.2016.03.016
https://doi.org/10.1016/j.bcp.2016.03.016
Publikováno v:
European journal of pharmacology. 819
Pharmacologically-induced pre- and post-conditioning represent attractive therapeutic strategies to reduce ischaemia/reperfusion injury during cardiac surgery and following myocardial infarction. We have previously reported that transglutaminase 2 (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77567d6313ff8d9a30c73ea4fd3c87cc
https://pubmed.ncbi.nlm.nih.gov/29208472
https://pubmed.ncbi.nlm.nih.gov/29208472
Autor:
John M. Dickenson, Carl P. Nelson, Alan J. Hargreaves, Falguni S. Vyas, David J. Boocock, Fiona Freeman
Tissue transglutaminase 2 (TG2) is modulated by protein kinase A (PKA) mediated phosphorylation: however, the precise mechanism(s) of its modulation by G-protein coupled receptors coupled to PKA activation are not fully understood. In the current stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449fa2977fb6339cf189a08caa3d4839
https://irep.ntu.ac.uk/id/eprint/31484/1/PubSub9005_Nelson.pdf
https://irep.ntu.ac.uk/id/eprint/31484/1/PubSub9005_Nelson.pdf
Autor:
Falguni S, Vyas, Carl P, Nelson, Fiona, Freeman, David J, Boocock, Alan J, Hargreaves, John M, Dickenson
Publikováno v:
European journal of pharmacology. 813
Tissue transglutaminase 2 (TG2) is modulated by protein kinase A (PKA) mediated phosphorylation: however, the precise mechanism(s) of its modulation by G-protein coupled receptors coupled to PKA activation are not fully understood. In the current stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a5d398c18fb5574dc22ad3e7a41ffdf
https://pubmed.ncbi.nlm.nih.gov/28754379
https://pubmed.ncbi.nlm.nih.gov/28754379
The PAC1 receptor and tissue transglutaminase (TG2) play important roles in neurite outgrowth and modulation of neuronal cell survival. In this study, we investigated the regulation of TG2 activity by the PAC1 receptor in retinoic acid-induced differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e1f360958f944bce6151871f451887
https://irep.ntu.ac.uk/id/eprint/32721/1/10235_Dickenson.pdf
https://irep.ntu.ac.uk/id/eprint/32721/1/10235_Dickenson.pdf
Publikováno v:
British Journal of Pharmacology. 171:3946-3960
Background and Purpose Tissue transglutaminase (TG2) has been shown to mediate cell survival in many cell types. In this study, we investigated whether the role of TG2 in cytoprotection was mediated by the activation of PKA and PKC in cardiomyocyte-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a132f56d036ca311fb95f9653e020e6
https://doi.org/10.1111/bph.12756
https://doi.org/10.1111/bph.12756