Zobrazeno 1 - 10
of 36
pro vyhledávání: '"John Lambris"'
Autor:
Hailey Harris, Sanjay Khandelwal, Lubica Rauova, John Lambris, Brandon Garcia, Douglas B. Cines, Gowthami M. Arepally
Publikováno v:
Blood. 140:8372-8373
Autor:
Grzegorz Sierpiński, David Rickard, Serge Abrate, Francisco José GARCÍA-PEÑALVO, John Lambris, Yi-Ping Phoebe Chen, Aldo Morselli
Publikováno v:
Journal of Sandwich Structures & Materials. 20:3-3
Publikováno v:
Scopus-Elsevier
Staphylococcal protein A (SpA), acting as a B cell superantigen, binds to the Fab region of human VH3+ Igs. Using SpA abrogated of its IgG Fc binding activity (Mod SpA) as a model B cell superantigen, we determined whether such an interaction causes
Publikováno v:
Scopus-Elsevier
We have screened a phage-displayed random peptide library for binding to C3b, the proteolytically activated form of complement component C3, and have identified a novel peptide that suppresses complement activation. This phage-displayed peptide bound
Publikováno v:
Scopus-Elsevier
Of the 30 distinct complement proteins recognized to date, C3 is probably the most versatile and multifunctional molecule known, interacting with at least 20 different proteins. It plays a critical role in both pathways of complement activation and p
Autor:
Jordan Woehl, Daphne Stapels, Brandon Garcia, Kasra Ramyar, Andrew Keightley, Maartje Ruyken, Georgia Sfyroera, Alexander Weber, Michal Zolkiewski, Daniel Ricklin, John Lambris, Suzan Rooijakkers, Brian Geisbrecht
Publikováno v:
The Journal of Immunology. 194:195.5-195.5
The pathogenic bacterium Staphylococcus aureus actively evades many aspects of human innate immunity by expressing a series of small inhibitory proteins. A number of these proteins inhibit the complement system, with the majority of S. aureus acting
Autor:
Sølvik, U. Ø., Haraldsen, G., Fiane, A. E., Boretti, E., John Lambris, Fung, M., Thorsby, E., Mollnes, T. E.
Publikováno v:
Publons
Scopus-Elsevier
Scopus-Elsevier
Whereas complement is a key mediator of hyperacute xenograft rejection, its role in acute vascular rejection (AVR) is a matter of controversy. AVR is associated with de novo synthesis of endothelial cell-derived inflammatory mediators, including the
Autor:
Florea Lupu, Robert Silasi-Mansat, Ravi Keshari, Glenn Peer, Narcis Popescu, Cristina Lupu, Fletcher Taylor, John Lambris, Gary Kinasewitz
Publikováno v:
The Journal of Immunology. 190:131.8-131.8
Sepsis-induced inflammation of the lung leads to acute respiratory distress syndrome (ARDS), which may trigger persistent fibrotic responses. We have developed a baboon model of E. coli sepsis-induced ARDS and characterized the long-term (6-24 months
Autor:
Antonis Ioannou, Peter Lapchak, Lakshmi Kannan, Poonam Rani, Jurandir Dalle Lucca, John Lambris, Tsokos George
Publikováno v:
The Journal of Immunology. 188:171.22-171.22
Ischemia reperfusion injury is a type of injury seen in clinical conditions, such as trauma, hemorrhagic shock, organ transplantation, revascularization processes, and autoimmune diseases like systemic lupus erythematosus. MRL/lpr mice due to their a
Publikováno v:
The Journal of Immunology. 184:86.23-86.23
Studies with animal models have shown that complement components C3a and C5a play an important role in the effector phase of allergic asthma. We have previously shown that C3a activates human CD34+-derived mast cells endogenously expressing G protein