Zobrazeno 1 - 10
of 65
pro vyhledávání: '"John L. Stebbins"'
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 1, Iss , Pp 100014- (2020)
The integration of salivary biomeasures in biobehavioral, psychophysiological, and clinical research has greatly expanded our ability to study the biopsychosocial processes underlying health. Much of this research, however, has failed to adequately a
Externí odkaz:
https://doaj.org/article/b6d44672fdf94d36877c793e9b5d49a6
Autor:
Maurizio Pellecchia, John C. Reed, Said Sebti, Nicholas Lawrence, Tyler A. Reed, Si Wang, Bainan Wu, Ziming Zhang, Russell Dahl, Li Yang, Jiazhi Sun, Dayong Zhai, John L. Stebbins, Jason Cellitti, Hongbin Yuan, Aras Emdadi, Michele F. Rega, Shinichi Kitada, Jun Wei
Guided by a combination of nuclear magnetic resonance binding assays and computational docking studies, we synthesized a library of 5,5′ substituted Apogossypol derivatives as potent Bcl-XL antagonists. Each compound was subsequently tested for its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604ac48de033a8db9e0fdc42766287b4
https://doi.org/10.1158/1535-7163.c.6531807
https://doi.org/10.1158/1535-7163.c.6531807
Autor:
Maurizio Pellecchia, John C. Reed, Said Sebti, Nicholas Lawrence, Tyler A. Reed, Si Wang, Bainan Wu, Ziming Zhang, Russell Dahl, Li Yang, Jiazhi Sun, Dayong Zhai, John L. Stebbins, Jason Cellitti, Hongbin Yuan, Aras Emdadi, Michele F. Rega, Shinichi Kitada, Jun Wei
Supplementary Data from Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95bebc910184fa8416d57f584ffdc4e
https://doi.org/10.1158/1535-7163.22485165
https://doi.org/10.1158/1535-7163.22485165
Autor:
Maurizio Pellecchia, Paul B. Fisher, Elena B. Pasquale, Shinichi Kitada, Neil A. Bhowmick, Ana Fernandez, Sandrine Billet, Sayantan Mitra, Bainan Wu, Ziming Zhang, Swadesh Das, John L. Stebbins, Roberta Noberini, Si Wang
PDF file - 328K, Scheme 1. Synthesis of YNH motif and dYNH motif Scheme S2. Synthetic route for YSA-PTX Figure S1. In vivo prostate cancer xenograft studies. Figure S2. EphA2 expression in RENCA renal carcinoma cells and PC3M prostate cancer cells. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d69e65203ba867b59145059bb021e77
https://doi.org/10.1158/1078-0432.22446387.v1
https://doi.org/10.1158/1078-0432.22446387.v1
Autor:
Maurizio Pellecchia, Paul B. Fisher, Elena B. Pasquale, Shinichi Kitada, Neil A. Bhowmick, Ana Fernandez, Sandrine Billet, Sayantan Mitra, Bainan Wu, Ziming Zhang, Swadesh Das, John L. Stebbins, Roberta Noberini, Si Wang
Purpose: YSA is an EphA2-targeting peptide that effectively delivers anticancer agents to prostate cancer tumors. Here, we report on how we increased the drug-like properties of this delivery system.Experimental Design: By introducing non-natural ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058e0bf87b375d073d5ba1bd8ddba197
https://doi.org/10.1158/1078-0432.c.6520734
https://doi.org/10.1158/1078-0432.c.6520734
Autor:
Alex Y. Strongin, Maurizio Pellecchia, Anton V. Cheltsov, Andrei V. Chernov, John L. Stebbins, Russell Dahl, Sergey A. Shiryaev, Vladislav S. Golubkov, Albert G. Remacle
PDF file - 69K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479b0244e0f61df76763459968b6c0a9
https://doi.org/10.1158/0008-5472.22394630.v1
https://doi.org/10.1158/0008-5472.22394630.v1
Autor:
Margaret Bennett-Brown, Anuraj Dhillon, John Crowley, John L. Stebbins, Steve W. Granger, Amanda Denes
This study explored the role of the hormone oxytocin in 49 emerging adult couples’ communication after sexual activity. Guided by the post sex disclosures model, the findings indicated that post sex oxytocin levels, but not increases in pre to post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d76c0ee50c78b5d87dd526f7750fddb
Autor:
Jun eWei, John L Stebbins, Shinichi eKitada, Rupesh eDash, Dayong eZhai, William J Placzek, Bainan eWu, Michele F Rega, Ziming eZhang, Elisa eBarile, Li eYang, Russell eDahl, Paul B. Fisher, John C Reed, Maurizio ePellecchia
Publikováno v:
Frontiers in Oncology, Vol 1 (2011)
Our focus in the past several years has been on the identification of novel and effective pan-Bcl-2 antagonists. We have recently reported a series of Apogossypolone (ApoG2) derivatives, resulting in the chiral compound (+/-) BI97D6. We report here t
Externí odkaz:
https://doaj.org/article/9da35fc70df844858b05d2972780c82d
Autor:
Douglas A. Granger, T. Hand, Thao Ha, Katrin M. Jaedicke, Crystal I. Bryce, John L. Stebbins, Marla J. Matin, Jenna L. Riis
Publikováno v:
Peptides. 91:58-64
This study addresses gaps in our understanding about the validity and utility of using salivary adiponectin to\ud index serum adiponectin levels. Matched blood and saliva samples were collected on a single occasion from\ud healthy adults (n=99; age 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200425a7654ce207ce5b2fabf58827d5
https://doi.org/10.1016/j.peptides.2017.03.006
https://doi.org/10.1016/j.peptides.2017.03.006
Autor:
Paul B. Fisher, Swadesh K. Das, Si Wang, Elisa Barile, Maurizio Pellecchia, Surya K. De, Luni Emdad, Devanand Sarkar, John L. Stebbins, Stephen J. Pandol, Bridget A. Quinn, Susan Morvaridi
Publikováno v:
Oncotarget
First line treatment for pancreatic cancer consists of surgical resection, if possible, and a subsequent course of chemotherapy using the nucleoside analogue gemcitabine. In some patients, an active transport mechanism allows gemcitabine to enter eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1298d813df4095b5020df7676d78b7
https://doi.org/10.18632/oncotarget.7931
https://doi.org/10.18632/oncotarget.7931