Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John L. Seed"'
Publikováno v:
Molecular Carcinogenesis. 3:243-250
The murine gene pro1 has been cloned from JB6 epidermal cell lines that are sensitive to neoplastic transformation by tumor promoters. Insensitive JB6 variants acquire susceptibility to neoplastic transformation by tumor promoters when transfected wi
Autor:
Glenn Hegamyer, Dolores Winterstein, Sylvie Poirier, Yi Sun, Nancy H. Colburn, John L. Seed, Sacha Malin, Ya Cao
Publikováno v:
Molecular Carcinogenesis. 4:297-307
A transforming activity associated with Chinese nasopharyngeal carcinoma (NPC) cell line CNE2 DNA has been identified by transfer into nontransformed promotion-sensitive mouse JB6(P+) C141 cells. To clone this transformation-associated sequence, we c
Publikováno v:
Journal of leukocyte biology. 47(4)
Explanted hepatic granulomas, eosinophils obtained from the peritoneal cavity of schistosome-infected mice, schistosome egg granuloma macrophages, alveolar macrophages, and activated peritoneal macrophages obtained from Listeria-infected mice were mi
Autor:
John L. Seed
Publikováno v:
Environmental Health Perspectives
The mutagenic activities of several phthalate esters have been evaluated in an 8-azaguanine resistance assay in Salmonella typhimurium. Three phthalate esters were found to be mutagenic: dimethyl phthalate, diethyl phthalate and di-n-butyl phthalate.
Publikováno v:
Experimental Parasitology. 50:33-44
l -Tyrosine, l -[3,4]dihydroxyphenylalanine ( l -DOPA), and dopamine are known to be in vitro substrates for Schistosoma mansoni phenol oxidase. Since all three compounds are present in the female schistosome, it is not clear which one serves as the
Publikováno v:
Photochemistry and photobiology. 50(5)
— Singlet oxygen activates the mutagenicity of several benzo[α]pyrene (BP) derivatives in the absence of mammalian metabolic action. This has been demonstrated using a separated-surface-sensitizer system for generating chemically pure singlet oxyg
Publikováno v:
JNCI: Journal of the National Cancer Institute.
The antischistosomal and antitrypanosomal drug trans-5-amino-3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazole [(SQ18506) CAS: 28754-68-9; (E)-amino-3-(2-(5-nitro-2-furyl)-vinyl)-1,2,4-oxadiazole] was carcinogenic for both male and female CD-1 mice when
Autor:
James L. Bennett, John L. Seed
Publikováno v:
Experimental parasitology. 49(3)
Phenol oxidase may be involved in the formation of the eggshell in Schistosoma mansoni. 3H-Labeled female S. mansoni proteins were polymerized in vitro following incubation with S. mansoni phenol oxidase and excess l -tyrosine. Peroxidase inhibitors,
Publikováno v:
JNCI: Journal of the National Cancer Institute.
In an attempt to dissociate the chemotherapeutic from the carcinogenic properties of the antischistosomal and antitrypanosomal nitrovinylfuran trans-5-amino-3-[2-(5-nitro-2-furyl)vinyl]1,2,4-oxadiazole [(SQ18506) CAS: 28754-68-9; (E)-5-amino-3-(2-(5-
Publikováno v:
Parasite immunology. 7(6)
Administration of the antioxidants 2(3)-tert-butyl-4-hydroxyanisole (BHA) or 5-(P-methoxyphenyl)-3H-1,2-dithiol-3-thione (ADT) to female CD-1 mice starting 4 weeks after infection with 70 cercariae of Schistosoma mansoni resulted in a decrease in the