Zobrazeno 1 - 10
of 35
pro vyhledávání: '"John L. Portis"'
Autor:
Frank Malik, John L. Portis, Kyle Rosenke, Leonard H. Evans, Duncan Hendrick, Angelo Kolokithas, Kim J. Hasenkrug, Mario L. Santiago, Lukas Swanson
Publikováno v:
Journal of Virology. 84:10933-10936
APOBEC proteins have evolved as innate defenses against retroviral infections. Human immunodeficiency virus (HIV) encodes the Vif protein to evade human APOBEC3G; however, mouse retroviruses do not encode a Vif homologue, and it has not been understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cfc593285ced15489a895e5210bce1
https://doi.org/10.1128/jvi.01023-10
https://doi.org/10.1128/jvi.01023-10
Autor:
Nancy D. Dalton, John L. Portis, Bruce Chesebro, Kirk U. Knowlton, Toshitaka Yajima, Matthew J. Trifilo, Eliezer Masliah, Kimberly Meade-White, Richard E. Race, Kirk L. Peterson, Yusu Gu, Michael B. A. Oldstone
Publikováno v:
Science. 313:94-97
We investigated extraneural manifestations in scrapie-infected transgenic mice expressing prion protein lacking the glycophosphatydylinositol membrane anchor. In the brain, blood, and heart, both abnormal protease-resistant prion protein (PrPres) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8526b8e112eab471458b6f0597e235fc
https://doi.org/10.1126/science.1128635
https://doi.org/10.1126/science.1128635
Publikováno v:
Journal of Virology. 77:12617-12629
FrCas E is a mouse retrovirus that causes a fatal noninflammatory spongiform neurodegenerative disease with pathological features strikingly similar to those induced by transmissible spongiform encephalopathy (TSE) agents. Neurovirulence is determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5db4fcbb4349cf6b4d4c31ce017629a
https://doi.org/10.1128/jvi.77.23.12617-12629.2003
https://doi.org/10.1128/jvi.77.23.12617-12629.2003
Autor:
John L. Portis
Publikováno v:
Virology. 296(1):1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f343c4d4b320a58839b8bb8e5f49d4
Publikováno v:
Journal of Virology. 75:11239-11243
Glycosylated Gag (Glycogag) is a transmembrane protein encoded by murine and feline oncornaviruses. While the protein is dispensible for virus replication, Glycogag-null mutants of a neurovirulent murine oncornavirus are slow to spread in vivo and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c46c9aed2439203449d9daab33b501
https://doi.org/10.1128/jvi.75.22.11239-11243.2001
https://doi.org/10.1128/jvi.75.22.11239-11243.2001
Publikováno v:
Journal of Virology. 72:5619-5625
Neonatal inoculation of CasBrE, an ecotropic murine retrovirus originally isolated from wild mice (16, 17), causes a neurologic disease manifested by noninflammatory spongiform degeneration primarily in areas of the central nervous system involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb710974f916f2fd2f5301adc043f04
https://doi.org/10.1128/jvi.72.7.5619-5625.1998
https://doi.org/10.1128/jvi.72.7.5619-5625.1998
Publikováno v:
The Journal of Immunology. 160:2905-2914
Immunity to genital tract infection with Chlamydia trachomatis is mediated by type 1 CD4+ T lymphocytes. To define the signals that govern lymphocyte trafficking to the genital mucosa, integrins expressed by infiltrating T cells and endothelial addre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed2a11ca92bffe52931e3cfe2dc862dd
https://doi.org/10.4049/jimmunol.160.6.2905
https://doi.org/10.4049/jimmunol.160.6.2905
Publikováno v:
Journal of Virology. 71:5355-5360
The neuroinvasiveness of a chimeric murine retrovirus, CasFrKP (KP), is dependent on the expression of glycosylated Gag (gp85gag). This viral protein is the product of alternate translation initiation 88 codons upstream of and in frame with the initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d4c67994ece95426151c36da3e6d3e
https://doi.org/10.1128/jvi.71.7.5355-5360.1997
https://doi.org/10.1128/jvi.71.7.5355-5360.1997
Publikováno v:
Journal of Virology. 70:8896-8907
CasBrE is a neurovirulent murine retrovirus which induces a spongiform myeloencephalopathy in susceptible mice. Genetic mapping studies have indicated that sequences responsible for neurovirulence reside within the env gene. To address the question o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec67bc35980f18c9355f18ae53eb87e6
https://doi.org/10.1128/jvi.70.12.8896-8907.1996
https://doi.org/10.1128/jvi.70.12.8896-8907.1996
Publikováno v:
Virology. 226:384-392
Neuroinvasiveness is a property of all neurovirulent murine retroviruses, although the factors which facilitate infection of the CNS are not understood. We previously showed that mutant MuLV which lack expression of an accessory protein, glycosylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10d8fdff84374fc49f7e0ffe71bfa84
https://doi.org/10.1006/viro.1996.0666
https://doi.org/10.1006/viro.1996.0666