Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John L. Pilon"'
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45774 (2012)
Avian scavengers, such as American crows (Corvus brachyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform enc
Externí odkaz:
https://doaj.org/article/4f1472048851486b8d9e98f1c9563712
Autor:
Danelle Okeson, John L. Pilon, Lowell A. Miller, Kurt C. VerCauteren, Christina M. Loiacono, Jack C. Rhyan, Sharon Lund
Publikováno v:
Neuroscience Letters. 429:161-164
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of domestic and wild cervids in North America. To address possible prevention regimens for CWD, we have used a mouse model system and the Rocky Mountain Laboratory (RML)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cd707e52c5838b1fad9f1a29451331
https://doi.org/10.1016/j.neulet.2007.10.015
https://doi.org/10.1016/j.neulet.2007.10.015
Autor:
Dane J. Clausen, Daniel L. Gustafson, Paul J. Lunghofer, Ryan J. Hansen, Barbara J. Rose, James E. Bradner, Brad Charles, Douglas H. Thamm, Robert M. Williams, John L. Pilon
Largazole is a potent class I-selective HDACi natural product isolated from the marine cyanobacteria Symploca sp. The purpose of this study was to test synthetic analogs of Largazole to identify potential scaffold structural modifications that would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8785473835571a2e28286144f73b4e
https://europepmc.org/articles/PMC4368451/
https://europepmc.org/articles/PMC4368451/
Publikováno v:
Journal of Biological Chemistry. 277:31038-31047
The PHO5 gene promoter is an important model for the study of gene regulation in the context of chromatin. Upon PHO5 activation the chromatin structure is reconfigured, but the mechanism of this transition remains unclear. Using templates reconstitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bee9410ac2d8830bece09de135f3b61
https://doi.org/10.1074/jbc.m204662200
https://doi.org/10.1074/jbc.m204662200
Publikováno v:
Protein Expression and Purification. 10:132-140
Transcription regulation in the cell occurs in the context of chromatin. It follows that a thorough investigation of the mechanism of transcription regulation must take into account the role of chromatin structure. Through classical and molecular gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54bfc832d18c695b0a180d3bf3d0d58
https://doi.org/10.1006/prep.1996.0716
https://doi.org/10.1006/prep.1996.0716
Autor:
Jack C. Rhyan, Michael W. Miller, Lisa L. Wolfe, John L. Pilon, Tracy A. Nichols, Tracy R. Davis, Katherine I. O'Rourke, Lowell A. Miller, Matt P. McCollum, Terry R. Spraker, Kurt C. VerCauteren, Pauline Nol, Thomas Gidlewski
Publikováno v:
Journal of wildlife diseases. 49(3)
Chronic wasting disease (CWD) adversely affects both wild and captive cervid populations. A vaccine to prevent CWD would be a highly desirable tool to aid in disease management. To this end, we tested in mule deer a combination of CWD vaccines consis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9224dc6f705e6dbe24be69f6b079a7
https://pubmed.ncbi.nlm.nih.gov/23778624
https://pubmed.ncbi.nlm.nih.gov/23778624
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45774 (2012)
PLoS ONE
PLoS ONE
Avian scavengers, such as American crows (Corvus brachyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdb6144d9310cc250891c1ce4f76f80
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23082115/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23082115/?tool=EBI
Publikováno v:
Journal of virological methods. 161(1)
Two serine protease enzymes, subtilisin 309 and subtilisin 309-v, were used to digest brain homogenates containing high levels of prion infectivity using mildly alkaline conditions to investigate prion decontamination methods. To establish that PrP(r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ade69ef87493ac7f54be4b87aafa59
https://pubmed.ncbi.nlm.nih.gov/19467265
https://pubmed.ncbi.nlm.nih.gov/19467265