Zobrazeno 1 - 10
of 78
pro vyhledávání: '"John L. Musachio"'
Autor:
Martin G. Pomper, John L. Musachio, Jiazhong Zhang, Ursula Scheffel, Yun Zhou, John Hilton, Atul Maini, Robert F. Dannals, Dean F. Wong, Alan P. Kozikowski
Publikováno v:
Molecular Imaging, Vol 1 (2002)
Imaging of glutamate carboxypeptidase II (GCP II), also known as N -acetylated α-linked l -amino dipeptidase (NAALADase), may enable study of glutamatergic transmission, prostate cancer, and tumor neovasculature in vivo. Our goal was to develop a pr
Externí odkaz:
https://doaj.org/article/6eb7dd6e45cf4dfba1dfa3c1e4b208fd
Autor:
John L. Musachio, Yun Zhou, Olivier Rousset, M Maris, Jeffrey Galecki, Melvin J. Reinhardt, Hong Fan, Mohab Alexander, Ahmet S. Dogan, Andrew Crabb, Ayon Nandi, John Hilton, Christopher J. Endres, Dean F. Wong, James Robert Brašić
Publikováno v:
Synapse. 63:339-358
(S)-5-[(123)I]iodo-3-(2-azetidinylmethoxy)pyridine (5-[(123)I]IA), a novel potent radioligand for high-affinity alpha4beta2* neuronal nicotinic acetylcholine receptors (nAChRs), provides a means to evaluate the density and the distribution of nAChRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d81f05d9059c878db655404dca9ec5
https://doi.org/10.1002/syn.20611
https://doi.org/10.1002/syn.20611
Autor:
Jinsoo Hong, Sami S. Zoghbi, Masao Imaizumi, Jonathan P. Gourley, Masahiro Fujita, Emmanuelle Briard, Robert B. Innis, John L. Musachio, Victor W. Pike, Robert L. Gladding
Publikováno v:
Synapse. 61:595-605
Peripheral benzodiazepine receptors (PBRs) are upregulated on activated microglia and are, thereby, biomarkers of cellular inflammation in brain. We recently developed two PET ligands with an aryloxyanilide structure to image PBRs and now evaluate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61bc78e77b9df27db5a0d75dc5adc13
https://doi.org/10.1002/syn.20394
https://doi.org/10.1002/syn.20394
Autor:
John L. Musachio, Christl A. Ruetzler, De Maw Chuang, Masahiro Fujita, Masao Imaizumi, Robert B. Innis, Victor W. Pike, Jinsoo Hong, Sami S. Zoghbi, Emmanuelle Briard, Hyun Ju Kim
Publikováno v:
Neuroscience Letters. 411:200-205
Peripheral benzodiazepine receptors (PBRs) are upregulated on activated microglia. We recently developed a promising positron emission tomography (PET) ligand, [ 11 C]PBR28, with high affinity and excellent ratio of specific to nonspecific binding. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89300ac6ead0c9c4562ec0f85ef3f9dc
https://doi.org/10.1016/j.neulet.2006.09.093
https://doi.org/10.1016/j.neulet.2006.09.093
Autor:
Michael V. Green, José A. Rodríguez-Gómez, Victor W. Pike, Sami S. Zoghbi, Ronald D.G. McKay, Jurgen Seidel, Seth N. Rivera, Robert B. Innis, Masanori Ichise, John L. Musachio, Jian Qiang Lu, Panayotis K. Thanos, Hiroshi Toyama, Iván Velasco, Frederick T. Chin, Jeih-San Liow
Publikováno v:
Stem Cells. 25:918-928
The derivation of dopamine neurons is one of the best examples of the clinical potential of embryonic stem (ES) cells, but the long-term function of the grafted neurons has not been established. Here, we show that, after transplantation into an anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4505cc18f8b1ccd602db850fd1489a1
https://doi.org/10.1634/stemcells.2006-0386
https://doi.org/10.1634/stemcells.2006-0386
Autor:
Jurgen Seidel, John L. Musachio, Jeih-San Liow, Jinsoo Hong, Sami S. Zoghbi, Masanori Ichise, H. Umesha Shetty, Robert B. Innis, Christer Halldin, Victor W. Pike
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 34:667-678
We aimed to determine the composition of radioactivity in rat brain after intravenous administration of the dopamine transporter radioligand, [(11)C]PE2I.PET time-activity curves (TACs) and regional brain distribution ex vivo were measured using no-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c845419771847f738589c3c4ed25ff
https://doi.org/10.1007/s00259-006-0277-1
https://doi.org/10.1007/s00259-006-0277-1
Autor:
Julie A. McCarron, Robert B. Innis, Jeih-San Liow, John L. Musachio, Jinsoo Hong, Sami S. Zoghbi, Victor W. Pike, Shuiyu Lu
Publikováno v:
Synapse. 61:96-105
Limited brain uptake of radioligands with otherwise optimal properties for imaging brain receptors can be improved by blocking the effect of P-glycoprotein (P-gp), an efflux pump at the blood-brain barrier. Using small animal positron emission tomogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3926d8745e057344de5070397ebc7e
https://doi.org/10.1002/syn.20348
https://doi.org/10.1002/syn.20348
Autor:
Michael V. Green, Matthew S. Crescenzo, Robert B. Innis, Jeih San Liow, Jinsoo Hong, John L. Musachio, Jian Qiang Lu, Dnyanesh Tipre, Nicholas Seneca, Sami S. Zoghbi, Antony D. Gee, Victor W. Pike, Masao Imaizumi, Masahiro Fujita, Vanessa Cropley, Jurgen Seidel
Publikováno v:
NeuroImage. 26:1201-1210
Objective: Phosphodiesterase 4 (PDE4) catabolizes the second messenger 3′, 5′-cyclic adenosine monophosphate and may play a critical role in brain diseases. Our aim was to quantify PDE4 in rats with positron emission tomography (PET). Methods: Hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0caef7c9f3febbde3988df8660548de7
https://doi.org/10.1016/j.neuroimage.2005.03.017
https://doi.org/10.1016/j.neuroimage.2005.03.017
Autor:
Robert M. Cohen, Douglass Vines, Lisheng Cai, Jurgen Seidel, Hiroshi Toyama, Mathew Crescenzo, Robert B. Innis, Jeih San Liow, Michael V. Green, Masanori Ichise, John L. Musachio, Kazuhiro Katada, Daniel Ye, Victor W. Pike, Jian Qiang Lu, Dnyanesh Tipre, David M. Jacobowitz, Sami S. Zoghbi, Jinsoo Hong
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 32:593-600
The purpose of this study was to evaluate the capacity of [11C]6-OH-BTA-1 and positron emission tomography (PET) to quantify beta-amyloid (Abeta) plaques in the Tg2576 mouse model of Alzheimer's disease (AD).PET imaging was performed with the NIH ATL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce867a0446dd9f9987c343f1442b4f5e
https://doi.org/10.1007/s00259-005-1780-5
https://doi.org/10.1007/s00259-005-1780-5
Autor:
Shuiyu Lu, Erik S Vermeulen, Håkan Wikström, Victor W. Pike, Jinsoo Hong, Frederick T. Chin, John L. Musachio
Publikováno v:
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 48(13), 971-981. Wiley
1-[2-(4-Fluorobenzoylamino)ethyl]-4-(7-methoxynaphthyl)piperazine (S14506) is one of the most potent and selective agonists at 5-HT1A receptors. For the purpose of prospective 5-HT1A receptor imaging with positron emission tomography and the investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7935814b1a907a8c97130570f52842
https://doi.org/10.1002/jlcr.1009
https://doi.org/10.1002/jlcr.1009