Zobrazeno 1 - 10
of 17
pro vyhledávání: '"John L. McCans"'
Autor:
Wendy Earle, Robert F. Bentley, J. Alberto Neder, Denis E. O'Donnell, Daniel M. Hirai, Michael E. Tschakovsky, Patti Staples, Joel T. Zelt, John L. Mccans, Joshua H. Jones
Publikováno v:
4.1 Clinical Physiology, Exercise and Functional Imaging.
Chronic heart failure (CHF) impairs skeletal muscle O 2 transport and utilization leading to restricted physical capacity. Dietary nitrate supplementation has been shown to improve vascular function, reduce the O 2 cost of muscle contraction and enha
Publikováno v:
The American Journal of Cardiology. 66:1422-1428
A total of 1,975 plasma diltiazem concentrations were obtained from 1,067 patients enrolled in a multicenter secondary intervention study of diltiazem after acute myocardial infarction. To evaluate the determinants and significance of diltiazem conce
Autor:
Brian P. Booth, Brian M. Bennett, James F. Brien, Kanji Nakatsu, Douglas A. Elliott, Gerald S. Marks, John L. Mccans
Publikováno v:
Biopharmaceutics & Drug Disposition. 11:663-677
Two large-bore capillary columns, one with dimethyl polysiloxane (HP-1) as the stationary phase and the other with phenyl (50 per cent) methyl (50 per cent) polysiloxane (DB-17), were used to develop gas-liquid chromatographic (GLC) assays for measur
Publikováno v:
The Journal of Clinical Pharmacology. 27:962-966
Bevantolol is a new, cardioselective beta-receptor antagonist that undergoes extensive hepatic biotransformation. To evaluate changes in the disposition of bevantolol produced by liver disease, a single 200-mg oral dose of bevantolol was administered
Publikováno v:
Proceedings of the National Academy of Sciences. 71:2449-2452
An antiserum was prepared against a highly purified Na + , K + -adenosine triphosphatase (ATP phosphohydrolase, EC 3.6.1.3). Purification and fractionation yielded two globulin components, one of which appears specific for a digitalis glycoside recep
Autor:
John L. Mccans, Andrew O. Davies
Publikováno v:
European Journal of Pharmacology. 59:65-73
The effects of ketamine and barbiturates (pentobarbital, thiopental, methohexital) were studied in an isolated rabbit Langendorff preparation. All agents tested depressed contractility. Ketamine, as well as the lipophilic barbiturates (thiopental, me
Publikováno v:
Journal of Electrocardiology. 10:375-378
Summary The purpose of this study was to determine if the computer-reported vectorcardiogram (VCG) had a notable impact on the cardiologist interpreter of the 12-lead scalar electrocardiogram (ECG). Three cardiologists read 100 12-lead scalar ECGs an
Publikováno v:
Annals of the New York Academy of Sciences. 242:577-597
Autor:
Albert M. Silver, John L. McCans, Emigdio A. Lopez, Mathew A. Araoye, Recep Ari, Richard J. Katz, Hanna A. Pipberger, Hubert V. Pipberger, Ross D. Fletcher, Gary W. Burggraf, John A. Milliken
Publikováno v:
Journal of Electrocardiology. 16:141-150
Summary Nine experienced electrocardiographers and the ECG computer program developed in the Veterans Administration (AVA 4.0) were evaluated against ECG-independent evidence of 180 patients' true diagnoses. A cross section of cardiac abnormalities w
Publikováno v:
Circulation Research. 35:439-447
The effects of verapamil on myocardial contractility were examined in perfused rabbit ventricular preparations. Verapamil (0.2 µ M ) decreased the time derivative of developed force (dF/dt) of the preparations paced at 90 beats/min to 39 ± 3% ( SE