Zobrazeno 1 - 10
of 95
pro vyhledávání: '"John L. Butenhoff"'
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 252-270 (2014)
Perfluorooctanoate (PFOA) is a fully fluorinated eight-carbon fatty acid analog with exceptional stability toward degradation that has been used as an industrial surfactant and has been detected in environmental and biological matrices. Exposures to
Externí odkaz:
https://doaj.org/article/3733c0c974c1474bb1e62db5daf9ba9b
Autor:
Jessica M. Caverly Rae, Steven R. Frame, Gerald L. Kennedy, John L. Butenhoff, Shu-Ching Chang
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 85-91 (2014)
Two chronic dietary studies, conducted years apart, with ammonium perfluorooctanoate (APFO) in Sprague Dawley rats have been previously reported. Although both included male 300 ppm dietary dose groups, only the later study, conducted in 1990–1992
Externí odkaz:
https://doaj.org/article/c7d0dfff3a9e461da2d79892b3e64295
Autor:
John L. Butenhoff, Shu Ching Chang, Yuan Tian, Robert G. Nichols, Bipin Rimal, Jeffrey M. Peters, Limin Zhang, Philip B. Smith, Emmanuel Hatzakis, Andrew D. Patterson
Publikováno v:
Toxicology
Perfluorooctane sulfonate (PFOS) is a persistent environmental chemical whose biological effects are mediated by multiple mechanisms. Recent evidence suggests that the gut microbiome may be directly impacted by and/or alter the fate and effects of en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9680e17d9534c99d55e7f2d68acb2f3
https://europepmc.org/articles/PMC7032741/
https://europepmc.org/articles/PMC7032741/
Autor:
Bradford D. Bagley, John L. Butenhoff, Alan Eveland, David J. Ehresman, George A. Parker, Jeffrey M. Peters, Shu Ching Chang
Publikováno v:
Toxicology and Industrial Health. 33:792-801
Choline is an essential nutrient utilized for phosphatidylcholine biosynthesis and lipoprotein packaging and secretion. Recently, choline supplementation has been used by athletes and the public for weight loss. However, the potential toxicological i
Publikováno v:
Toxicology Letters. 271:38-49
Perfluorooctane sulfonyl fluoride (POSF) was a volatile starting material in the production of perfluorooctane sulfonate (PFOS), a stable surfactant that has been extensively studied due to its ubiquitous environmental distribution and slow clearance
Autor:
John L. Butenhoff, Jeremiah D. Zitzow, Jeffrey M. Peters, David J. Ehresman, Kendall B. Wallace, Shu Ching Chang, Alan Eveland, Bradford D. Bagley, George A. Parker
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 160(2)
Perfluorooctane sulfonate (PFOS) is an environmentally persistent chemical. Dietary 100 ppm PFOS fed to male mice and rats for 4 weeks caused hepatic steatosis through an unknown mechanism. Choline deficient diets can cause hepatic steatosis. A hepat
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 252-270 (2014)
Toxicology Reports
Toxicology Reports
Perfluorooctanoate (PFOA) is a fully fluorinated eight-carbon fatty acid analog with exceptional stability toward degradation that has been used as an industrial surfactant and has been detected in environmental and biological matrices. Exposures to
Autor:
Yi M. Weaver, David J. Ehresman, John L. Butenhoff, Wen Zhao, Jeremiah D. Zitzow, Shu-Ching Chang, Bruno Hagenbuch
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 156(1)
Perfluoroalkyl sulfonates (PFSAs) such as perfluorohexane sulfonate (PFHxS) and perfluorooctane sulfonate (PFOS) have very long serum elimination half-lives in humans, and preferentially distribute to serum and liver. The enterohepatic circulation of
Autor:
John L. Butenhoff, Limin Zhang, Jeffrey M. Peters, Andrew D. Patterson, David J. Ehresman, Mainak Dutta, Shu Ching Chang, Bradford D. Bagley, Philip B. Smith, Prasad Krishnan
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 153(1)
The mechanisms underlying perfluorooctane sulfonate (PFOS)-induced steatosis remain unclear. The hypothesis that PFOS causes steatosis and other hepatic effects by forming an ion pair with choline was examined. C57BL/6 mice were fed either a control
Autor:
Geary W. Olsen, David J. Ehresman, Barbara A. Gibson, John L. Butenhoff, Larry R. Zobel, Betsy D. Buehrer
Publikováno v:
Journal of Occupational & Environmental Medicine. 54:974-983
To examine in a longitudinal occupational assessment whether changes in serum concentrations of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) are associated with changes in non-high-density lipoprotein (HDL) cholesterol.Baseline a