Zobrazeno 1 - 7
of 7
pro vyhledávání: '"John L. Aull"'
Publikováno v:
Microchemical Journal. 19:210-218
Polyacrylamide gel electrophoresis was used to resolve as many as three protein components from incubation mixtures containing the inhibitor, 5-fluoro-2′-deoxyuridylate, the cofactor, 5,10-methylene tetrahydrofolate, and thymidylate synthetase. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0af46c1dadc2e511ea260461a1d31cf
https://doi.org/10.1016/0026-265x(74)90076-9
https://doi.org/10.1016/0026-265x(74)90076-9
Publikováno v:
Journal of Biological Chemistry. 251:1303-1310
Ternary complexes of thymidylate synthetase (Form II and Form III), which are composed of the enzyme, 5-fluorodeoxyuridylate, and the natural isomer of methylenetetrahydrofolate, were generated by titrating thymidylate synthetase (Form I) in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ecc50cb95d115a37c6a672dbdab34b5
https://doi.org/10.1016/s0021-9258(17)33741-9
https://doi.org/10.1016/s0021-9258(17)33741-9
Publikováno v:
Archives of Biochemistry and Biophysics. 165:805-808
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cb2ea620f04d0a50a88b1070674fe9
https://doi.org/10.1016/0003-9861(74)90310-5
https://doi.org/10.1016/0003-9861(74)90310-5
Publikováno v:
Journal of Biological Chemistry. 249:1167-1172
SUMMARY Carboxypeptidase A treated with diisopropylphosphorofluoridate (DFP) present at catalytic levels causes the complete inactivation of thymidylate synthetase. The rate of this inactivation is shown to be proportional to the concentration of car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b175b176be409eb019b1c130a45409
https://doi.org/10.1016/s0021-9258(19)42956-6
https://doi.org/10.1016/s0021-9258(19)42956-6
Publikováno v:
Journal of Biological Chemistry. 247:566-571
Preparative polyacrylamide gel electrophoresis has been used in the final stages of purification to prepare horse serum cholinesterase which was at least 95% pure, as judged by analytical polyacrylamide gel electrophoresis. The starting material, alr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d38374eaa3d893bd64db2e03ab6a1ccc
https://doi.org/10.1016/s0021-9258(19)45740-2
https://doi.org/10.1016/s0021-9258(19)45740-2
Publikováno v:
Biochemistry. 16(4)
Thymidylate synthetase (methylenetetrahydrofolate:deoxyuridylate C-methyltransferase) from Lactobacillus casei was progressively inactivated when incubated at 25 degrees C, pH 6.8, in the presence of trans-Pt(NH3)2Cl2. The inhibition appeared to be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e17f29e9bf1264ed5e5dada707cce2
https://pubmed.ncbi.nlm.nih.gov/402146
https://pubmed.ncbi.nlm.nih.gov/402146
Publikováno v:
Journal of inorganic biochemistry. 22(4)
Thymidylate synthase from methotrexate-resistant Lactobacillus casei rapidly lost about 90% of its catalytic activity when incubated with an equimolar concentration of IO4- at 0 degree C. Nearly complete inhibition resulted when the IO4- concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8abc373d4afd75f46bb2d840babb614
https://pubmed.ncbi.nlm.nih.gov/6097648
https://pubmed.ncbi.nlm.nih.gov/6097648