Výsledky vyhledávání - "John L Thain"

Akademický článek

Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target.

Autor: Katharine S Dobb, Sarah J Kaye, Nicola Beckmann, John L Thain, Lubomira Stateva, Mike Birch, Jason D Oliver

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)

Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded

Externí odkaz: https://doaj.org/article/1cd24085abc54adea0bfd6032719577a

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Transport of the antibacterial agent (6S)-6-fluoroshikimate and other shikimate analogues by the shikimate transport system of Escherichia coli

Autor: Wright W. Nichols, Gareth M. Davies, David A. Jude, John L. Thain, Christopher D.C. Ewart

Publikováno v: Biochimica et biophysica acta. 1279(2)

We show that the antibacterial agent, (6S)-6-fluoroshikimate, is a substrate for the shikimate transport system of Escherichia coli because in exchange-diffusion experiments it displaced intracellular [14C]shikimate with the same kinetics as did unla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c171b6168743dfae0ecb7538fc0900
https://pubmed.ncbi.nlm.nih.gov/8603077

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