Zobrazeno 1 - 10
of 180
pro vyhledávání: '"John L Robertson"'
Autor:
John L Robertson, Ryan S Senger, Janine Talty, Pang Du, Amr Sayed-Issa, Maggie L Avellar, Lacey T Ngo, Mariana Gomez De La Espriella, Tasaduq N Fazili, Jasmine Y Jackson-Akers, Georgi Guruli, Giuseppe Orlando
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270914 (2022)
We developed and tested a method to detect COVID-19 disease, using urine specimens. The technology is based on Raman spectroscopy and computational analysis. It does not detect SARS-CoV-2 virus or viral components, but rather a urine 'molecular finge
Externí odkaz:
https://doaj.org/article/fea3929dd3eb4bc3b42052e45d1b1968
Autor:
Herbert M Huttanus, Tommy Vu, Georgi Guruli, Andrew Tracey, William Carswell, Neveen Said, Pang Du, Bing G Parkinson, Giuseppe Orlando, John L Robertson, Ryan S Senger
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237070 (2020)
Bladder cancer (BCA) is relatively common and potentially recurrent/progressive disease. It is also costly to detect, treat, and control. Definitive diagnosis is made by examination of urine sediment, imaging, direct visualization (cystoscopy), and i
Externí odkaz:
https://doaj.org/article/2cebe689a7c644c99ea7f97f0e765853
Autor:
Ryan S Senger, Meaghan Sullivan, Austin Gouldin, Stephanie Lundgren, Kristen Merrifield, Caitlin Steen, Emily Baker, Tommy Vu, Ben Agnor, Gabrielle Martinez, Hana Coogan, William Carswell, Varun Kavuru, Lampros Karageorge, Devasmita Dev, Pang Du, Allan Sklar, James Pirkle, Susan Guelich, Giuseppe Orlando, John L Robertson
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227281 (2020)
Raman Chemometric Urinalysis (RametrixTM) was used to discern differences in Raman spectra from (i) 362 urine specimens from patients receiving peritoneal dialysis (PD) therapy for end-stage kidney disease (ESKD), (ii) 395 spent dialysate specimens f
Externí odkaz:
https://doaj.org/article/088f56963925434fa51e88ebe7182881
Autor:
Ryan S Senger, Varun Kavuru, Meaghan Sullivan, Austin Gouldin, Stephanie Lundgren, Kristen Merrifield, Caitlin Steen, Emily Baker, Tommy Vu, Ben Agnor, Gabrielle Martinez, Hana Coogan, William Carswell, Lampros Karageorge, Devasmita Dev, Pang Du, Allan Sklar, Giuseppe Orlando, James Pirkle, John L Robertson
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222115 (2019)
Raman chemometric urinalysis (Rametrix™) was used to analyze 235 urine specimens from healthy individuals. The purpose of this study was to establish the "range of normal" for Raman spectra of urine specimens from healthy individuals. Ultimately, s
Externí odkaz:
https://doaj.org/article/148bf7751c3b462584ace9ad6a712888
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Raman spectroscopy (RS) is used increasingly for disease detection, including diseases of the nervous system (CNS). This Perspective presents RS basics and how it has been applied to disease detection. Research that focused on using a novel Raman-bas
Externí odkaz:
https://doaj.org/article/84602bb5a1cd47c5ba9ade0a47e85c38
Autor:
Robert E Neal, John H Rossmeisl, John L Robertson, Christopher B Arena, Erica M Davis, Ravi N Singh, Jonathan Stallings, Rafael V Davalos
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64559 (2013)
Irreversible electroporation (IRE) is a non-thermal focal ablation technique that uses a series of brief but intense electric pulses delivered into a targeted region of tissue, killing the cells by irrecoverably disrupting cellular membrane integrity
Externí odkaz:
https://doaj.org/article/70304cd53a294a3cbe10303781cff7a1
Autor:
Paulo A Garcia, John H Rossmeisl, John L Robertson, John D Olson, Annette J Johnson, Thomas L Ellis, Rafael V Davalos
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50482 (2012)
The blood-brain-barrier (BBB) presents a significant obstacle to the delivery of systemically administered chemotherapeutics for the treatment of brain cancer. Irreversible electroporation (IRE) is an emerging technology that uses pulsed electric fie
Externí odkaz:
https://doaj.org/article/e0d4c0f247f6452fbef0800afebf1b6c
Autor:
John L. Robertson, Nikolas Dervisis, John Rossmeisl, Marlie Nightengale, Daniel Fields, Cameron Dedrick, Lacey Ngo, Amr Sayed Issa, Georgi Guruli, Giuseppe Orlando, Ryan S. Senger
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionThe presence of cancer in dogs was detected by Raman spectroscopy of urine samples and chemometric analysis of spectroscopic data. The procedure created a multimolecular spectral fingerprint with hundreds of features related directly to t
Externí odkaz:
https://doaj.org/article/a45efcf21fe646ed9be82b5ab13d8500
Autor:
Yukitaka Kani, Thomas E. Cecere, Kevin Lahmers, Tanya LeRoith, Kurt L. Zimmerman, Scott Isom, Fang‐Chi Hsu, Waldemar Debinksi, John L. Robertson, John H. Rossmeisl
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 3, Pp 1384-1391 (2019)
Abstract Background Stereotactic brain biopsy (SBB) is a technique that allows for definitive diagnosis of brain lesions. Little information is available regarding the diagnostic utility of SBB in dogs with intracranial diseases. Objective To investi
Externí odkaz:
https://doaj.org/article/350248c1c27d4d93b080583b071623f1
Autor:
Timothy J. O’Brien, Melvin F. Lorenzo, Yajun Zhao, Robert E. Neal II, John L. Robertson, S. Nahum Goldberg, Rafael V. Davalos
Publikováno v:
International Journal of Hyperthermia, Vol 36, Iss 1, Pp 952-962 (2019)
Purpose: This study evaluates the effects of various pulsing paradigms, on the irreversible electroporation (IRE) lesion, induced electric current, and temperature changes using a perfused porcine liver model. Materials and methods: A 4-monopolar ele
Externí odkaz:
https://doaj.org/article/14b73fe373a94bb7b3bdd66e21974e7d