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pro vyhledávání: '"John Kresevic"'
Publikováno v:
Powder Technology. 335:427-439
In the production of pharmaceutical tablets and capsules, a lubricant such as magnesium stearate is often added to the powder blend or granulation in order to reduce friction and, in some cases, minimize sticking to the manufacturing equipment surfac
Autor:
John Kresevic, Daniel O. Blackwood, Matthew P. Mullarney, Jeffrey Moriarty, Joseph Kushner, William R. Ketterhagen
Publikováno v:
Drug Development and Industrial Pharmacy. 44:1350-1356
The purpose of this work was to develop a methodology that quantifies the extent of shear induced during an encapsulation process and show how formulation composition and manufacturing process designs can be changed to reduce the negative impact on d