Zobrazeno 1 - 10
of 346
pro vyhledávání: '"John Koreth"'
Autor:
Veronica Donato, Haesook T. Kim, Peter Stowe, Carol G. Reynolds, Jerome Ritz, John Koreth, Jennifer S. Whangbo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic graft-versus-host disease (cGVHD) remains a frequent cause of non-relapse morbidity and mortality after allogeneic hematopoietic stem cell transplantation. In our single center trials of low-dose interleukin-2 (LD IL-2), the immunomodulatory
Externí odkaz:
https://doaj.org/article/eaef601912cd48ae98a193d2011a17c3
Autor:
Roman M. Shapiro, Grace C. Birch, Guangan Hu, Juliana Vergara Cadavid, Sarah Nikiforow, Joanna Baginska, Alaa K. Ali, Mubin Tarannum, Michal Sheffer, Yasmin Z. Abdulhamid, Benedetta Rambaldi, Yohei Arihara, Carol Reynolds, Max S. Halpern, Scott J. Rodig, Nicole Cullen, Jacquelyn O. Wolff, Kathleen L. Pfaff, Andrew A. Lane, R. Coleman Lindsley, Corey S. Cutler, Joseph H. Antin, Vincent T. Ho, John Koreth, Mahasweta Gooptu, Haesook T. Kim, Karl-Johan Malmberg, Catherine J. Wu, Jianzhu Chen, Robert J. Soiffer, Jerome Ritz, Rizwan Romee
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Background Responses to conventional donor lymphocyte infusion for postallogeneic hematopoietic cell transplantation (HCT) relapse are typically poor. Natural killer (NK) cell–based therapy is a promising modality to treat post-HCT relapse.Methods
Externí odkaz:
https://doaj.org/article/2699fa01730746f2b44f722f69c72b21
Autor:
Benedetta Rambaldi, Haesook T. Kim, Yohei Arihara, Takeru Asano, Carol Reynolds, Mariah Manter, Max Halpern, Augustine Weber, John Koreth, Corey Cutler, Mahasweta Gooptu, Sarah Nikiforow, Vincent T. Ho, Joseph H. Antin, Rizwan Romee, Jeanette Ampudia, Cherie Ng, Stephen Connelly, Robert J. Soiffer, Jerome Ritz
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
CD6 is a co-stimulatory receptor expressed on T cells that binds activated leukocyte cell adhesion molecule (ALCAM), expressed on antigen presenting cells, epithelial and endothelial tissues. The CD6-ALCAM pathway plays an integral role in modulating
Externí odkaz:
https://doaj.org/article/028cbeb056154b0f986dae1e00d73c08
Autor:
Christopher J. Gibson, John Koreth
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/b48465e89d6d457b880ee6b3cdd45c16
Autor:
Haesook T. Kim, Peter O. Baker, Erin Parry, Matthew Davids, Edwin P. Alyea, Vincent T. Ho, Corey Cutler, John Koreth, Mahasweta Gooptu, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Jerome Ritz, Robert J. Soiffer, Catherine J. Wu, Jennifer R. Brown
Publikováno v:
Haematologica, Vol 106, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/7dd653f984984ac8967ac5f65f2ffb3c
Autor:
Jennifer S. Whangbo, Haesook T. Kim, Nikola Mirkovic, Lauren Leonard, Samuel Poryanda, Sophie Silverstein, Soomin Kim, Carol G. Reynolds, Sharmila C. Rai, Kelly Verrill, Michelle A. Lee, Steven Margossian, Christine Duncan, Leslie Lehmann, Jennifer Huang, Sarah Nikiforow, Edwin P. Alyea, III, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Bruce R. Blazar, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, John Koreth
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2550-2561 (2019)
Abstract: Low-dose interleukin-2 (IL-2) therapy for chronic graft-versus-host disease (cGVHD) generates a rapid rise in plasma IL-2 levels and CD4+CD25+CD127−Foxp3+ regulatory T-cell (CD4Treg) proliferation, but both decrease over time despite cont
Externí odkaz:
https://doaj.org/article/7451b006929a41fca3f95f87e7835ef3
Autor:
Max Jan, Matthew J. Leventhal, Elizabeth A. Morgan, Jordan C. Wengrod, Anwesha Nag, Samantha D. Drinan, Bruce M. Wollison, Matthew D. Ducar, Aaron R. Thorner, Scott Leppanen, Jane Baronas, Jonathan Stevens, William J. Lane, Natasha Kekre, Vincent T. Ho, John Koreth, Corey S. Cutler, Sarah Nikiforow, Edwin P. Alyea, III, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, R. Coleman Lindsley, Benjamin L. Ebert
Publikováno v:
Blood Advances, Vol 3, Iss 14, Pp 2199-2204 (2019)
Abstract: Immune evasion is a hallmark of cancer and a central mechanism underlying acquired resistance to immune therapy. In allogeneic hematopoietic cell transplantation (alloHCT), late relapses can arise after prolonged alloreactive T-cell control
Externí odkaz:
https://doaj.org/article/dd67bff001a141b5ae1e7eda4fd3a48d
Autor:
Mahasweta Gooptu, John Koreth
Publikováno v:
Haematologica, Vol 105, Iss 11 (2020)
Acute graft-versus-host disease (aGvHD) is induced by immunocompetent alloreactive T lymphocytes in the donor graft responding to polymorphic and non-polymorphic host antigens and causing inflammation in primarily the skin, gastrointestinal tract and
Externí odkaz:
https://doaj.org/article/29dd3d9832e7405782b527227998e447
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Externí odkaz:
https://doaj.org/article/25517430840e4508a8c8b5d6765c3b45
Autor:
Vincent T. Ho, Haesook T. Kim, Natalie Bavli, Martin Mihm, Olga Pozdnyakova, Matthias Piesche, Heather Daley, Carol Reynolds, Nicholas C. Souders, Corey Cutler, John Koreth, Edwin P. Alyea, Joseph H. Antin, Jerome Ritz, Glenn Dranoff, Robert J. Soiffer
Publikováno v:
Blood Advances, Vol 1, Iss 24, Pp 2269-2279 (2017)
Abstract: We report a clinical trial testing vaccination of autologous myeloblasts admixed with granulocyte-macrophage colony-stimulating factor secreting K562 cells after allogeneic hematopoietic stem cell transplantation (HSCT). Patients with myelo
Externí odkaz:
https://doaj.org/article/b9cd8c81fce84bbb89eabfa774379357