Zobrazeno 1 - 10
of 75
pro vyhledávání: '"John Koomen"'
Autor:
Ryan T. Bishop, Tao Li, Raghunandan R. Alugubelli, Mostafa Nasr, Karl J. Nyman, Praneeth Sudalagunta, Mark Meads, Jeremy Frieling, Niveditha Nerlakanti, Marilena Tauro, Oliver Hampton, Bin Fang, Steven Grant, John Koomen, Ariosto Siqueira Silva, Kenneth H. Shain, Conor C. Lynch
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100539- (2024)
Externí odkaz:
https://doaj.org/article/521fc9dd9d7d46f098490ae18ec77b15
Autor:
Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin Luo, Tiandao Li, John Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y. Feng, Kiran Mahajan, Nupam P. Mahajan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The testicular androgen biosynthesis is well understood, however, how cancer cells gauge dwindling androgen to dexterously initiate its de novo synthesis remained elusive. We uncover dual-phosphorylated form of sterol regulatory element-bind
Externí odkaz:
https://doaj.org/article/6796f1304f8b4aaf971cec547d08d83d
Autor:
Bin Fang, John Koomen, Paul Stewart, Alex M Jaeger, William Rideout, Tyler Jacks, Andrew Weeden, Anika Ali, Victoria Izumi, Emma Sanders
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/bbeb0658bb9044afb29fc9c9c3091144
Autor:
Karen E Ross, Guolin Zhang, Cuneyt Akcora, Yu Lin, Bin Fang, John Koomen, Eric B Haura, Mark Grimes
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 3, p e1010690 (2023)
We analyzed large-scale post-translational modification (PTM) data to outline cell signaling pathways affected by tyrosine kinase inhibitors (TKIs) in ten lung cancer cell lines. Tyrosine phosphorylated, lysine ubiquitinated, and lysine acetylated pr
Externí odkaz:
https://doaj.org/article/92f7c2e322a64533a13b1a50cb4a282b
Autor:
Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin Luo, Tiandao Li, John Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y. Feng, Kiran Mahajan, Nupam P. Mahajan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/bd78901281fb43119a54924b66bf7d3f
Autor:
AGM Mostofa, Allison Distler, Mark B. Meads, Eva Sahakian, John J. Powers, Alexandra Achille, David Noyes, Gabriela Wright, Bin Fang, Victoria Izumi, John Koomen, Rupal Rampakrishnan, Tuan P. Nguyen, Gabriel De Avila, Ariosto S. Silva, Praneeth Sudalagunta, Rafael Renatino Canevarolo, Maria D. Coelho Siqueira Silva, Raghunandan Reddy Alugubelli, Hongyue A. Dai, Amit Kulkarni, William S. Dalton, Oliver A. Hampton, Eric A. Welsh, Jamie K. Teer, Alexandre Tungesvik, Kenneth L. Wright, Javier Pinilla-Ibarz, Eduardo M. Sotomayor, Kenneth H. Shain, Jason Brayer
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
The clinical utility of histone/protein deacetylase (HDAC) inhibitors in combinatorial regimens with proteasome inhibitors for patients with relapsed and refractory multiple myeloma (MM) is often limited by excessive toxicity due to HDAC inhibitor pr
Externí odkaz:
https://doaj.org/article/7fe4645c54d74f3db9e69957840e8738
Autor:
Joseph Markowitz, Anders Berglund, Saurabh Garg, Eric Welsh, Bin Fang, Yuliana Hernandez, Trevor Rose, Jhanelle Gray, John Koomen, James Mule
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/15d27429e07748538fa6e96c868abedb
Autor:
David Noyes, Chao Wang, Scott Antonia, Jose Conejo-Garcia, Bin Fang, John Koomen, Jamie Teer, Jiqiang Yao, Carmen Anadon, Ana Landin, Xiaoqing Yu, Dongliang Du, Zachary Thompson, Sungjune Kim, Dung-Tsa Chen, Eric Haura, Ben Creelan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/b82381bc23544c179ad3a9adddf575ab
Autor:
Shengchen Lin, Chongbiao Huang, Jianwei Sun, Oana Bollt, Xiuchao Wang, Eric Martine, Jiaxin Kang, Matthew D Taylor, Bin Fang, Pankaj K Singh, John Koomen, Jihui Hao, Shengyu Yang
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 12, Pp n/a-n/a (2019)
Abstract The mitochondrial deoxynucleotide triphosphate (dNTP) is maintained by the mitochondrial deoxynucleoside salvage pathway and dedicated for the mtDNA homeostasis, and the mitochondrial deoxyguanosine kinase (DGUOK) is a rate‐limiting enzyme
Externí odkaz:
https://doaj.org/article/2b1bcd46ad9241968307c033ac2143a2
Autor:
Gregory Watson, Daniel Lester, Hui Ren, Connor M. Forsyth, Elliot Medina, David Gonzalez Perez, Lancia Darville, Jiqiang Yao, Vince Luca, John Koomen, Ling Cen, Eric Lau
Publikováno v:
Cells, Vol 10, Iss 6, p 1310 (2021)
Alterations in genes encoding for proteins that control fucosylation are known to play causative roles in several developmental disorders, such as Dowling-Degos disease 2 and congenital disorder of glycosylation type IIc (CDGIIc). Recent studies have
Externí odkaz:
https://doaj.org/article/9c3d552b38d54a819d2aac9602abe5b4