Zobrazeno 1 - 10
of 23
pro vyhledávání: '"John Kanazawa"'
Autor:
Karine Dubé, John Kanazawa, Hursch Patel, Michael Louella, Laurie Sylla, Jeff Sheehy, Lynda Dee, Jeff Taylor, Jen Adair, Kim Anthony-Gonda, Boro Dropulić, John A. Sauceda, Michael J. Peluso, Steven G. Deeks, Jane Simoni
Publikováno v:
BMC Medical Ethics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background HIV cure research involving cell and gene therapy has intensified in recent years. There is a growing need to identify ethical standards and safeguards to ensure cell and gene therapy (CGT) HIV cure research remains valued and acc
Externí odkaz:
https://doaj.org/article/f7bf2f0c25664f168230bc9dc1a4b9d9
Autor:
Karine Dubé, John Kanazawa, Christopher Roebuck, Steven Johnson, William B. Carter, Lynda Dee, Beth Peterson, Kenneth M. Lynn, Linden Lalley-Chareczko, Emily Hiserodt, Sukyung Kim, Daniel Rosenbloom, Brad R. Evans, Melanie Anderson, Daria J. Hazuda, Lisa Shipley, Kevin Bateman, Bonnie J. Howell, Karam Mounzer, Pablo Tebas, Luis J. Montaner
Publikováno v:
HIV Research & Clinical Practice, Vol 23, Iss 1, Pp 120-135 (2022)
Background People with HIV (PWH) and community members have advocated for the development of a home-based viral load test device that could make analytical treatment interruptions (ATIs) less burdensome. Objective We assessed community acceptability
Externí odkaz:
https://doaj.org/article/d5f0d32e8dbc42dd958bb6aeb88bedaa
Autor:
John Kanazawa, Sara Gianella, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Christopher Christensen, Hursch Patel, Samuel Ndukwe, Stephen A. Rawlings, Steven Hendrickx, Susan Little, Brandon Brown, Davey Smith, Karine Dubé
Publikováno v:
BMC Medical Ethics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background One of the next frontiers in HIV research is focused on finding a cure. A new priority includes people with HIV (PWH) with non-AIDS terminal illnesses who are willing to donate their bodies at the end-of-life (EOL) to advance the
Externí odkaz:
https://doaj.org/article/ee341c50d8c1468499212ea22cea5a63
Autor:
Karine Dubé, John Kanazawa, Lynda Dee, Jeff Taylor, John A. Sauceda, Sara Gianella, Davey Smith, Steven G. Deeks, Michael J. Peluso
Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background An increasing number of HIV cure trials involve combining multiple potentially curative interventions. Until now, considerations for designing and implementing complex combination HIV cure trials have not been thoroughly considere
Externí odkaz:
https://doaj.org/article/f0671fb818744d6a8b7790caf789deca
Autor:
Karine Dubé, John Kanazawa, Jeff Taylor, Lynda Dee, Nora Jones, Christopher Roebuck, Laurie Sylla, Michael Louella, Jan Kosmyna, David Kelly, Orbit Clanton, David Palm, Danielle M. Campbell, Morénike Giwa Onaiwu, Hursch Patel, Samuel Ndukwe, Laney Henley, Mallory O. Johnson, Parya Saberi, Brandon Brown, John A. Sauceda, Jeremy Sugarman
Publikováno v:
BMC Medical Ethics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background The pursuit of a cure for HIV is a high priority for researchers, funding agencies, governments and people living with HIV (PLWH). To date, over 250 biomedical studies worldwide are or have been related to discovering a safe, effe
Externí odkaz:
https://doaj.org/article/07f6f61cbb5a4380b506701dd273bf3a
Autor:
Karine Dubé, John Kanazawa, Lynda Dee, Jeff Taylor, Danielle M. Campbell, Brandon Brown, Mallory O. Johnson, Parya Saberi, John A. Sauceda, Jeremy Sugarman, Michael J. Peluso
Publikováno v:
HIV Research & Clinical Practice, Vol 22, Iss 1, Pp 14-30 (2021)
Background Background: Analytical treatment interruptions (ATIs) in HIV cure-related research can result in trial participants becoming viremic with HIV, placing HIV-negative sexual partners at elevated risk of acquiring HIV. Objective Objective:Our
Externí odkaz:
https://doaj.org/article/1543969179294c2f9d356ad7c333cb18
Autor:
John Kanazawa, Sara Gianella, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Christopher Christensen, Hursch Patel, Samuel Ndukwe, Stephen Rawlings, Steven Hendrickx, Susan Little, Brandon Brown, Davey Smith, Karine Dubé
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254148 (2021)
BackgroundA unique window of opportunity currently exists to generate ethical and practical considerations presented by interventional HIV cure-related research at the end-of-life (EOL). Because participants would enroll in these studies for almost c
Externí odkaz:
https://doaj.org/article/085d198d99df48ac9490a4186d499b92
Autor:
Karine Dubé, Kelly E. Perry, Kushagra Mathur, Megan Lo, Sogol S. Javadi, Hursch Patel, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Lynda Dee, Danielle Campbell, John Kanazawa, David Smith, Sara Gianella, Judith D. Auerbach, Parya Saberi, John A. Sauceda
Publikováno v:
Journal of Virus Eradication, Vol 6, Iss 4, Pp 100008- (2020)
Introduction: The question of what motivates people to participate in research is particularly salient in the HIV field. While participation in HIV research was driven by survival in the 1980’s and early 1990’s, access to novel therapies became t
Externí odkaz:
https://doaj.org/article/10c10163618e4a5ab422f4c1c56d1cd7
Autor:
Karine Dubé, Loreen Willenberg, Lynda Dee, Laurie Sylla, Jeff Taylor, Christopher Roebuck, David Palm, Danielle Campbell, Luke Newton, Hursch Patel, Kelly E. Perry, John Kanazawa, Jo Gerrard, Brandon Brown, Parya Saberi, John A. Sauceda, Michael J. Peluso
Publikováno v:
Journal of Virus Eradication, Vol 6, Iss 4, Pp 100017- (2020)
For over a decade, the binary concepts of ‘sterilizing’ versus ‘functional’ cure have provided an organizing framework for the field of HIV cure-related research. In this article, we examine how the expression ‘functional cure’ is employe
Externí odkaz:
https://doaj.org/article/54db53869f6e46828d6625f0f983ea00
Autor:
Karine, Dubé, John, Kanazawa, Christopher, Roebuck, Steven, Johnson, William B, Carter, Lynda, Dee, Beth, Peterson, Kenneth M, Lynn, Linden, Lalley-Chareczko, Emily, Hiserodt, Sukyung, Kim, Daniel, Rosenbloom, Brad R, Evans, Melanie, Anderson, Daria J, Hazuda, Lisa, Shipley, Kevin, Bateman, Bonnie J, Howell, Karam, Mounzer, Pablo, Tebas, Luis J, Montaner
Publikováno v:
HIV researchclinical practice.
People with HIV (PWH) and community members have advocated for the development of a home-based viral load test device that could make analytical treatment interruptions (ATIs) less burdensome.We assessed community acceptability of a novel home-based