Zobrazeno 1 - 10
of 18
pro vyhledávání: '"John K. Zehmer"'
Autor:
René Bartz, Wen-Hong Li, Barney Venables, John K. Zehmer, Mary R. Roth, Ruth Welti, Richard G.W. Anderson, Pingsheng Liu, Kent D. Chapman
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 4, Pp 837-847 (2007)
Lipid droplets are accumulations of neutral lipids surrounded by a monolayer of phospholipids and associated proteins. Recent proteomic analysis of isolated droplets suggests that they are part of a dynamic organelle system that is involved in membra
Externí odkaz:
https://doaj.org/article/11f661ee80bf400185ef9a30aa71f4f5
Autor:
Katherine Luby-Phelps, Isamu Z. Hartman, Russell A. DeBose-Boyd, Pingsheng Liu, Richard G.W. Anderson, John K. Zehmer, Youngah Jo
Publikováno v:
The Journal of Biological Chemistry
Sterol-induced binding to Insigs in the endoplasmic reticulum (ER) allows for ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in cholesterol synthesis. This ubiquitination marks reductase for recognition by
Autor:
Pingsheng Liu, Blaine Bisel, Joachim Seemann, René Bartz, Richard G.W. Anderson, John K. Zehmer
Publikováno v:
Journal of Cell Science. 122:3694-3702
Lipid droplets are sites of neutral lipid storage thought to be actively involved in lipid homeostasis. A popular model proposes that droplets are formed in the endoplasmic reticulum (ER) by a process that begins with the deposition of neutral lipids
Publikováno v:
PROTEOMICS. 9:914-921
All cells have the capacity to accumulate neutral lipids and package them into lipid droplets. Recent proteomic analyses indicate that lipid droplets are not simple lipid storage depots, but rather complex organelles that have multiple cellular funct
Publikováno v:
Journal of Cell Science. 121:1852-1860
AAM-B is a putative methyltransferase that is a resident protein of lipid droplets. We have identified an N-terminal 28 amino acid hydrophobic sequence that is necessary and sufficient for targeting the protein to droplets. This sequence will also in
Autor:
Ginette Serrero, Kent D. Chapman, Pingsheng Liu, Joachim Seemann, René Bartz, Richard G.W. Anderson, John K. Zehmer
Publikováno v:
Molecular Biology of the Cell. 18:3015-3025
Mono-ADP-ribosylation is emerging as an important posttranslational modification that modulates a variety of cell signaling pathways. Here, we present evidence that mono-ADP-ribosylation of the transcriptional corepressor C terminal binding protein,
Autor:
Jeffrey R. Hazel, John K Zehmer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1664:108-116
Homeoviscous adaptation (HVA), the thermal conservation of membrane fluidity/order at different body temperatures, has been observed to varying degrees in different membranes. However, HVA has not been studied in raft and non-raft regions of the plas
Autor:
Jeffrey R. Hazel, John K Zehmer
Publikováno v:
Journal of Experimental Biology. 206:1657-1667
SUMMARY Rafts are cholesterol- and sphingolipid-enriched microdomains of the plasma membrane (PM) that organize many signal transduction pathways. Interactions between cholesterol and saturated lipids lead to patches of liquid-ordered membrane (rafts
Autor:
Aprile L. Pilon, Melissa E Winn, Yan Cai, Shioko Kimura, William K. Gillette, Jacek Lubkowski, John K. Zehmer
Secretoglobin (SCGB) 3A2 is a member of the SCGB gene superfamily of small secreted proteins, predominantly expressed in lung airways. We hypothesize that human SCGB3A2 may exhibit anti-inflammatory, growth factor, and antifibrotic activities and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ede351b95e626e4076fe8e54c4eed25
https://europepmc.org/articles/PMC3920213/
https://europepmc.org/articles/PMC3920213/
An important advance in countercurrent chromatography (CCC) carried out in open flow-tubing coils, rotated in planetary centrifuges, is the new design to spread out the tubing in spirals. More spacing between the tubing was found to significantly inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029de23e4a9818a490a1ccbea207e17b
https://europepmc.org/articles/PMC3159842/
https://europepmc.org/articles/PMC3159842/