Zobrazeno 1 - 10
of 31
pro vyhledávání: '"John K. Swartzendruber"'
Autor:
Robert Theodore Vasileff, Brown Raymond Frank, J. F. Quay, F. T. Counter, J. A. Webber, E. O. Davidson, Terry D. Lindstrom, Jeffrey S. Kasher, William Henry Walker Lunn, Mitchell I. Steinberg, J. M. Jun. Morin, J. A. Eudaly, Paul W. Ensminger, R. E. Koehler, Allen S. Katner, Michael Dean Kinnick, John K. Swartzendruber, Jan R. Turner, David A. Preston, J. K. Shadle, Walter E. Wright, J. F. Stucky, K. D. Kurz, John L. Ott, Karen M. Zimmerman
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386baf125ef02cf683bca51f026f46c4
https://doi.org/10.1002/chin.199104334
https://doi.org/10.1002/chin.199104334
Publikováno v:
ChemInform. 21
La synthese d'[halogeno ethyl-2] benzo [6] thiophenes et de leur dioxydes-1,1 se fait a partir de lithio-2 benzo [b] thiophenes et de leurs dioxydes-1,1; les substitutions nucleophiles de ces composes vis-a-vis d'amines, de thiols et d'alcools ont et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a7b3616d112b5d953fd5ca23a6d797
https://doi.org/10.1002/chin.199001167
https://doi.org/10.1002/chin.199001167
Autor:
Jack B. Deeter, Donald B. Boyd, David C. Hunden, John Michael Morin, Lowell D. Hatfield, Bennie Joe Foster, John E. Munroe, Noel D. Jones, Michael Dean Kinnick, Joseph N. Hobbs, William Joseph Hornback, Norris E. Allen, Jack B. Campbell, David G. Vogt, T. K. Elzey, John K. Swartzendruber
Publikováno v:
Tetrahedron. 45:1905-1928
Computational chemistry made possible the prediction of the three-dimensional structures of γ-lactam analogues of penems and carbapenems before the analogues were made. Molecular superpositioning showed that these novel structures with a 7β-acylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16a1e4b81c8dcf01c6e7519fa6244dd
https://doi.org/10.1016/s0040-4020(01)80055-7
https://doi.org/10.1016/s0040-4020(01)80055-7
Publikováno v:
Tetrahedron Letters. 25:2531-2534
The major product from the thermolysis and photolysis of C(3)-azido cephem 2 is the ring expanded 1,4,6-thiadiazepine azetidinone.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::215c1b59b55242ed11278cc3c221c8fb
https://doi.org/10.1016/s0040-4039(01)81223-5
https://doi.org/10.1016/s0040-4039(01)81223-5
Autor:
Harold E. Obsorne, Jack B. Deeter, Donn G. Wishka, John T. Ott, William J. Wheeler, R. E. Koehler, Michael Dean Kinnick, John K. Swartzendruber, Don Richard Finley
Publikováno v:
The Journal of Antibiotics. 39:111-120
A series of 7 beta-[2-(5-aminooxadiazol-3-yl)-2-Z-methoximinoacetamido] -3-cephem-4-carboxylic acids (7a-g) were synthesized and evaluated microbiologically Although somewhat less active than cefotaxime 7a-g showed good antimicrobial activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c22fcb2ec5d2b4d18de45cc95077859
https://doi.org/10.7164/antibiotics.39.111
https://doi.org/10.7164/antibiotics.39.111
Publikováno v:
Tetrahedron Letters. 28:289-292
Bicyclic pyrazolidinones were synthesized as γ-lactam analogs of the β-lactam antibiotics. Several of these compounds exhibited broad spectrum in vitro antibacterial activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8bb1adb104b5caf8868e3e21c65589c
https://doi.org/10.1016/s0040-4039(00)95709-5
https://doi.org/10.1016/s0040-4039(00)95709-5
Autor:
David W. Robertson, Hayes Js, Noel D. Jones, Joseph H. Krushinski, G. D. Pollock, John K. Swartzendruber
Publikováno v:
Journal of Medicinal Chemistry. 30:623-627
The cardiotonic 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3- pyridazinyl)-2H-indol-2-one (1, LY195115) is a potent, competitive inhibitor (Ki = 80 nM) of sarcoplasmic reticulum derived phosphodiesterase (SR-PDE). Moreover, the compound is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a59704691f82681e65c8da199a273f0b
https://doi.org/10.1021/jm00387a007
https://doi.org/10.1021/jm00387a007
Publikováno v:
Chemische Berichte. 118:5009-5015
Uber die Struktur der roten Acylierungsprodukte von Pyridazinylhydrazonen Bei der Acylierung von Pyridazinylhydrazonen (3) mit Saurechloriden oder Anhydriden in Benzol entstehen scharlachrote Triazolo[4,3-b]pyridazine (4), deren Struktur durch Rontge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81d0225ea6c0da82c011cc5f02911791
https://doi.org/10.1002/cber.19851181232
https://doi.org/10.1002/cber.19851181232
Autor:
H. Wilson, R. F. Kauffman, Hayes Js, T. K. Elzey, E. E. Beedle, John K. Swartzendruber, David W. Robertson, Noel D. Jones
Publikováno v:
Journal of Medicinal Chemistry. 29:635-640
The cardiotonic drug milrinone (1,6-dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile) is superior to its analogue amrinone (5-amino-[3,4'-bipyridin]-6(1H)-one) by virtue of its greater potency and reduced side effect profile. We confirmed init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af426c8d73113421ebba957daa4d93ec
https://doi.org/10.1021/jm00155a009
https://doi.org/10.1021/jm00155a009
Publikováno v:
The Journal of Organic Chemistry. 54:3311-3317
La synthese d'[halogeno ethyl-2] benzo [6] thiophenes et de leur dioxydes-1,1 se fait a partir de lithio-2 benzo [b] thiophenes et de leurs dioxydes-1,1; les substitutions nucleophiles de ces composes vis-a-vis d'amines, de thiols et d'alcools ont et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c90e8231283a4a32b275c6380bf7b73
https://doi.org/10.1021/jo00275a013
https://doi.org/10.1021/jo00275a013