Zobrazeno 1 - 10 of 72 pro vyhledávání: '"John K. Simmons"'
1
Akademický článek
Automated next-generation profiling of genomic alterations in human cancers
Autor: Laurel A. Keefer, James R. White, Derrick E. Wood, Kelly M. R. Gerding, Kenneth C. Valkenburg, David Riley, Christopher Gault, Eniko Papp, Christine M. Vollmer, Amy Greer, James Hernandez, Paul M. McGregor, Adriana Zingone, Bríd M. Ryan, Kristen Deak, Shannon J. McCall, Michael B. Datto, James L. Prescott, John F. Thompson, Gustavo C. Cerqueira, Siân Jones, John K. Simmons, Abigail McElhinny, Jennifer Dickey, Samuel V. Angiuoli, Luis A. Diaz, Victor E. Velculescu, Mark Sausen
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The genomic profiling of tumours has not been widely adopted in the clinic due to technical and practical hurdles. Here, the authors develop PGDx elio tissue complete, a scalable, standardised and FDA-cleared test comprising a targeted gene panel and
Externí odkaz: https://doaj.org/article/e4aa27119f0a4f1f9ac75c8283f59ea8
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2
Akademický článek
Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex
Autor: David R. Calabrese, Xiang Chen, Elena C. Leon, Snehal M. Gaikwad, Zaw Phyo, William M. Hewitt, Stephanie Alden, Thomas A. Hilimire, Fahu He, Aleksandra M. Michalowski, John K. Simmons, Lindsey B. Saunders, Shuling Zhang, Daniel Connors, Kylie J. Walters, Beverly A. Mock, John S. Schneekloth
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Targeting noncoding nucleic acids with small molecules represents an important and significant challenge in chemical biology and drug discovery. Here the authors characterize DC-34, a small molecule that exhibits selective binding to specific G4 stru
Externí odkaz: https://doaj.org/article/d45674f52573447395e321fc6dc2bc80
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Plný text Recenzováno Digitální knihovna AV ČR
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