Zobrazeno 1 - 10
of 12
pro vyhledávání: '"John K. Nyanjui"'
Autor:
Sarah C. Gilbert, Victor Riitho, Julius Osaso, Fredrick O. Onono, Roger Pelle, Duncan Mwangi, Evans L. N. Taracha, Elias Awino, John K. Nyanjui, W. Ivan Morrison, Jean-Christophe Audonnet, Yoshikazu Honda, Declan J. McKeever, Evelyne Abuya, Mat Yamage, Niall D. MacHugh, Anthony M. Muthiani, Pierre van der Bruggen, Cecelia Muriuki, Ramadhan S. Mwakubambanya, Simon P. Graham, Ferdinand Mbwika, Etienne P. de Villiers, James Gachanja, Shirley A. Ellis, Rosemary Saya
Publikováno v:
Graham, S P, Pelle, R, Yamage, M, Mwangi, D M, Honda, Y, Mwakubambanya, R S, de Villiers, E P, Abuya, E, Awino, E, Gachanja, J, Mbwika, F, Muthiani, A M, Muriuki, C, Nyanjui, J K, Onono, F O, Osaso, J, Riitho, V, Saya, R M, Ellis, S A, McKeever, D J, MacHugh, N D, Gilbert, S C, Audonnet, J C, Morrison, W I, van der Bruggen, P & Taracha, E L 2008, ' Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva ', Infection and Immunity, vol. 76, no. 2, pp. 685-694 . https://doi.org/10.1128/IAI.01244-07
Immunity against the bovine intracellular protozoan parasiteTheileria parvahas been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells fromT. parva-immune cattle of different major histocompatibility complex (MHC) genotypes hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e9fc8ddaca2c02fde7f5299cccf6c3
https://ora.ox.ac.uk/objects/uuid:cd52a113-54a5-4e55-b90e-a1f4f12d0e41
https://ora.ox.ac.uk/objects/uuid:cd52a113-54a5-4e55-b90e-a1f4f12d0e41
Autor:
John K. Nyanjui, Roger Pelle, Yoshikazu Honda, Guy H. Palmer, Jocelyn Bray, James Gachanja, Waithaka Mwangi, Duncan Mwangi, Wendy C. Brown, Evans L. N. Taracha, Simon P. Graham
Publikováno v:
Veterinary Immunology and Immunopathology. 140:244-251
Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing recruitment and activation o
Autor:
Vishvanath Nene, P.R. Spooner, Richard P. Bishop, Catherine Nkonge, John K. Nyanjui, Stephen Mwaura, J.M. Katende, David Odongo, Antony Musoke, John Rowlands, Samuel Mbogo, Subhash Morzaria
Publikováno v:
Vaccine. 23:3084-3095
Two recombinant vaccines against Theileria parva, based on a near full-length version of the sporozoite surface antigen p67 (p67 635 ), or an 80 amino acid C-terminal section (p67C), were evaluated by exposure of immunized cattle to natural tick chal
Publikováno v:
Veterinary Immunology and Immunopathology. 85:23-32
There is growing evidence that immunity of cattle to Cowdria ruminantium infection is mediated by T lymphocytes. C. ruminantium antigens that stimulate these responses are therefore of considerable importance to the development of a sub-unit vaccine
Publikováno v:
Europe PubMed Central
The polymorphic immunodominant molecule (PIM) of Theileria parva is expressed by the schizont and sporozoite stages of the parasite. We have recently cloned the cDNA encoding the PIM antigen from two stocks of the parasite: the cattle-derived T. parv
Publikováno v:
Molecular and Biochemical Parasitology. 73:165-177
The polymorphic, immunodominant molecule (PIM) of Theileria parva is the predominant antigen recognized by sera from infected cattle and by monoclonal antibodies (mAb) used to differentiate parasite strains. As such, the antigen is under consideratio
Autor:
Evans L. N. Taracha, P.W.N. Kanyari, Rosemary Saya, John K. Nyanjui, Duncan Mwangi, Lavoisier Akoolo, Elias Awino, Simon P. Graham, Roger Pelle
Publikováno v:
Veterinary immunology and immunopathology. 121(3-4)
East Coast fever (ECF) is a highly fatal lymphoproliferative disease of cattle caused by Theileria parva, a tick-borne intracellular apicomplexan parasite. Parasite antigens that are targets of protective cytotoxic T lymphocyte (CTL) responses are re
Publikováno v:
Annals of the New York Academy of Sciences. 849:372-374
Autor:
Elias Awino, Evans L. N. Taracha, Rolf Hecker, Rosemary Saya, John K. Nyanjui, Daniel Ngugi, Vishvanath Nene, Simon P. Graham
Publikováno v:
Veterinary immunology and immunopathology. 115(3-4)
Enhancement of the induction of cytotoxic T-cell responses by immunostimulatory CpG oligodeoxynucleotides has been described in humans and mouse models. The present study attempted to address whether CpG has a similar effect in cattle. Immunisation o
Autor:
Julius Osaso, Yoshikazu Honda, Trushar Shah, James Gachanja, Evelyne Abuya, Elias Awino, Anthony M. Muthiani, Roger Pelle, Duncan Mwangi, J.C. Audonnet, Pierre van der Bruggen, Rosemary Saya, John K. Nyanjui, Claude Wildmann, David Ndegwa, Ferdinand Mbwika, Subhash Morzaria, Malcolm J. Gardner, Evans L. N. Taracha, Sheena M. Loosmore, Mat Yamage, Nyerhovwo J. Tonukari, Simon P. Graham, Claire M. Fraser, Anthony E. Luyai, Etienne P. de Villiers, Sarah C. Gilbert, Ian Maudlin, Fredrick O. Onono, Moses N. Njahira, Richard P. Bishop, E. Jane Glew, Vishvanath Nene
Publikováno v:
Proceedings of the National academy of sciences of the United States of America, Vol. 103, no. 9, p. 3286-3291 (2006)
East Coast fever, caused by the tick-borne intracellular apicomplexan parasiteTheileria parva, is a highly fatal lymphoproliferative disease of cattle. The pathogenic schizont-induced lymphocyte transformation is a unique cancer-like condition that i