Zobrazeno 1 - 10
of 11
pro vyhledávání: '"John K. Leach"'
Publikováno v:
Journal of Investigative Medicine. 50:61-66
Background A rapid change in length of cardiac muscle during isometric contraction is followed by developed force that is less than appropriate for the new length because of deactivation of the contractile system. Length change deactivation may have
Autor:
Elizabeth L. Albright, William P. Reed, John K. Leach, Thomas W. Chick, Rudy P Chavez, Simeon E. Goldblum
Publikováno v:
American Heart Journal. 112:84-88
Mechanisms of death in pneumococcal disease are poorly understood. We have previously shown that intravenous pneumococcal products in dogs caused a mean decrease in cardiac output of 58%. The present study used measurements of the force and rate of c
Autor:
Charles E. Stremsterfer, Betty J. Skipper, John K. Leach, David L. Millis, Richard D. Strickland
Publikováno v:
American Journal of Health-System Pharmacy. 34:709-712
The effect of long-term storage in polyvinyl chloride bags on the biological activity and the chemical stability of isoproterenol was studied. A freshly prepared solution of isoproterenol, isoproterenol solution stored for six months and isoprotereno
Autor:
D. E. Van Epps, John K. Leach, William P. Reed, Richard E. Crowell, T. Anaya, Thomas W. Chick, Dennis E. Chenoweth
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 255:H1227-H1231
Products of the complement (C) cascade may have direct effects on pulmonary vascular tissue and contribute to pulmonary vasoconstriction in states of C activation. We studied the effects of C3a, a C-derived vasoactive peptide, on isolated rabbit hila
Autor:
John K. Leach, Robert S. Alexander
Publikováno v:
American Journal of Physiology-Legacy Content. 209:935-940
To investigate the cause of the rapid relaxation observed in the epinephrine-stimulated heart, stress relaxation and distensibility have been measured in the isolated perfused cat heart and in isolated papillary muscles. During epinephrine stimulatio
Publikováno v:
American Heart Journal. 83:688-693
Characteristically, a patient with pheochromocytoma presents with paroxysmal or sustained hypertension and related symptoms. Occasionally the predominant manifestation of such a tumor may be congestive heart failure associated with primary myocardial
Publikováno v:
Chest. 73:658-660
Publikováno v:
Life sciences. 17(2)
The effects of epinephrine and caffeine on isometric rabbit papillary muscle preparations were observed after maximum peak tension was produced by adjustment of initial length and Ca++ concentration. Without change in peak tension, epinephrine caused
Publikováno v:
The American journal of the medical sciences. 276(1)
The present study was designed to investigate pharmacological vasodilation in patients with chronic obstructive pulmonary disease (COPD). This may have long-term therapeutic implications. Sublingual nitroglycerin (GTN) was administered to 16 patients
Publikováno v:
The American journal of cardiology. 10
Hemodynamic data obtained at left heart catheterization in 110 instances of mitral valve disease have been presented, with particular emphasis on the value of this procedure in differentiating mitral stenosis from regurgitation. Configuration of the