Zobrazeno 1 - 10
of 14
pro vyhledávání: '"John K. Barrows"'
Autor:
John K. Barrows, Baicheng Lin, Colleen E. Quaas, George Fullbright, Elizabeth N. Wallace, David T. Long
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
BRD4 is a multifunctional regulator of chromatin binding that plays a direct role in DNA double-strand break repair. BRD4 interacts with the SWI/SNF chromatin remodeling complex and resection machinery to promote homologous recombination.
Externí odkaz:
https://doaj.org/article/9b8da46283df4f609e78c109dd9d206e
Autor:
John K. Barrows, Michael W. Van Dyke
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Regulation of gene expression is a vital component of cellular biology. Transcription factor proteins often bind regulatory DNA sequences upstream of transcription start sites to facilitate the activation or repression of RNA polymerase. Res
Externí odkaz:
https://doaj.org/article/f9d33326bd3c46d48a5823c6cb126752
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10042 (2021)
Transcription regulatory proteins, also known as transcription factors, function as molecular switches modulating the first step in gene expression, transcription initiation. Cyclic-AMP receptor proteins (CRPs) and fumarate and nitrate reduction regu
Externí odkaz:
https://doaj.org/article/ac9d58bec8834d63bd5c34f913f86d2a
Autor:
John K Barrows, Michael W Van Dyke
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263322 (2022)
Biolayer interferometry (BLI) is a widely utilized technique for determining macromolecular interaction dynamics in real time. Using changes in the interference pattern of white light reflected off a biosensor tip, BLI can determine binding parameter
Externí odkaz:
https://doaj.org/article/81ace25c02934b6d96d01691d6faede0
Autor:
Robert R Bowers, Christian M Jones, Edwin A Paz, John K Barrows, Kent E Armeson, David T Long, Joe R Delaney
Publikováno v:
Nucleic Acids Research. 50:3673-3692
Haploinsufficiency drives Darwinian evolution. Siblings, while alike in many aspects, differ due to monoallelic differences inherited from each parent. In cancer, solid tumors exhibit aneuploid genetics resulting in hundreds to thousands of monoallel
Publikováno v:
J Bacteriol
D-block metal cations are essential for most biological processes; however, excessive metal exposure can be deleterious to the survival of microorganisms. To tightly control heavy metal regulation, prokaryotic organisms have developed several mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586deea0e6a432c7191adb5fa336ab5f
https://europepmc.org/articles/PMC9664954/
https://europepmc.org/articles/PMC9664954/
Autor:
John K. Barrows, Michael W. Van Dyke
Publikováno v:
Journal of Biological Chemistry. 299:104759
Autor:
John K. Barrows, David T. Long
Publikováno v:
Journal of Biological Chemistry. 294:19645-19654
Soluble extracts prepared from Xenopus eggs have been used extensively to study various aspects of cellular and developmental biology. During early egg development, transcription of the zygotic genome is suppressed. As a result, traditional extracts
Autor:
John K. Barrows, Baicheng Lin, Colleen E. Quaas, George Fullbright, Elizabeth N. Wallace, David T. Long
Publikováno v:
Nature communications. 13(1)
Double-strand breaks (DSBs) are one of the most toxic forms of DNA damage and represent a major source of genomic instability. Members of the bromodomain and extra-terminal (BET) protein family are characterized as epigenetic readers that regulate ge
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 10042, p 10042 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 10042, p 10042 (2021)
Transcription regulatory proteins, also known as transcription factors, function as molecular switches modulating the first step in gene expression, transcription initiation. Cyclic-AMP receptor proteins (CRPs) and fumarate and nitrate reduction regu