Zobrazeno 1 - 10
of 289
pro vyhledávání: '"John K. Olynyk"'
Autor:
Alan Wigg, Jonathan Tibballs, Richard Woodman, Katherine Stuart, Hien Le, Stuart K. Roberts, John K. Olynyk, Simone I. Strasser, Michael Wallace, Jarad Martin, Annette Haworth, Nicholas Hardcastle, Kee Fong Loo, Colin Tang, Yoo Young Lee, Julie Chu, Richard De Abreu Lourenco, Adam Koukourou, Diederick De Boo, Kate McLean, Jackie Buck, Rohit Sawhney, Amanda Nicoll, Anouk Dev, Marnie Wood, Alicia Braund, Martin Weltman, Richard Khor, Miriam Levy, Tim Wang, Michael Potter, James Haridy, Ashok Raj, Oliver Duncan, Amany Zekry, Natalie Collier, James O’Beirne, Catherine Holliday, Yuvnik Trada, Jaw Tronidjaja, Jacob George, David Pryor
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Therapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver dysfunction and comorbidities. Many patients with early-stage HCC do not receive curative-intent
Externí odkaz:
https://doaj.org/article/6d523d1c82814f78b6224ff1b323717f
Autor:
John K. Olynyk, Timothy G. St. Pierre, James Chen, David M. Frazer, Louise E. Ramm, Grant A. Ramm
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 4, Pp 454-460 (2024)
Background and Aims: Hemostatic iron regulator-hemochromatosis can result in progressive iron-loading and advanced hepatic fibrosis in some individuals. We studied total body and hepatic iron loading to determine whether the distribution of iron-load
Externí odkaz:
https://doaj.org/article/50d919de2ba24274bbad82dc5e69ce81
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Advanced hepatic fibrosis occurs in up to 25% of individuals with C282Y homozygous hemochromatosis. Our aim was to determine whether human leukocyte antigen (HLA)-A3 and B7 alleles act as genetic modifiers of the likelihood of advanced hepat
Externí odkaz:
https://doaj.org/article/f8279f1f11e04eefb28049986831f0d4
Autor:
Ashika D. Maharaj, John Lubel, Eileen Lam, Paul J. Clark, Oliver Duncan, Jacob George, Gary P. Jeffrey, Lara Lipton, Howard Liu, Geoffrey McCaughan, Eu‐Ling Neo, Jennifer Philip, Simone I. Strasser, Katherine Stuart, Alexander Thompson, Jonathan Tibballs, Thomas Tu, Michael C. Wallace, Alan Wigg, Marnie Wood, Amany Zekry, Elysia Greenhill, Liane J. Ioannou, Golo Ahlenstiel, Kaye Bowers, Stephen J. Clarke, Anouk Dev, Michael Fink, Mark Goodwin, Christos S. Karapetis, Miriam T. Levy, Kate Muller, James O'Beirne, David Pryor, James Seow, Nicholas Shackel, Caroline Tallis, Nick Butler, John K. Olynyk, Kate Reed‐Cox, John R. Zalcberg, Stuart K. Roberts
Publikováno v:
Hepatology Communications, Vol 6, Iss 11, Pp 3260-3271 (2022)
Abstract Although there are several established international guidelines on the management of hepatocellular carcinoma (HCC), there is limited information detailing specific indicators of good quality care. The aim of this study was to develop a core
Externí odkaz:
https://doaj.org/article/9a7c14322e6647adba6c1e30e2bfeb06
Autor:
Malik Janjua, Matthew Knuiman, Mark Divitini, Brendan McQuillan, John K. Olynyk, Gary P. Jeffrey, Leon A. Adams
Publikováno v:
Hepatology Communications, Vol 6, Iss 3, Pp 526-534 (2022)
Low‐level alcohol consumption is associated with reduced cardiovascular disease (CVD) in the general population. It is unclear whether this association is seen in patients with nonalcoholic fatty liver disease (NAFLD) who have an increased risk of
Externí odkaz:
https://doaj.org/article/fd304f7830224151aebea5c166424258
Autor:
Sim Yee Ong, Tiffany Khoo, Amanda J. Nicoll, Lyle Gurrin, Thomas Worland, Puraskar Pateria, Louise E. Ramm, Adam Testro, Gregory J. Anderson, Richard Skoien, Lawrie W. Powell, Grant A. Ramm, John K. Olynyk, Martin B. Delatycki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Aspartate aminotransferase-to-platelet ratio index (APRI) and Fibrosis-4 Index (Fib4) have been validated against liver biopsy for detecting advanced hepatic fibrosis in HFE hemochromatosis. We determined the diagnostic utility for advanced
Externí odkaz:
https://doaj.org/article/7d1d5a7b6a9c4eeb9724bc31eb9c0869
Autor:
Reece Jefferies, Harish Puttagunta, Anoushka Krishnan, Ashley Irish, Ramyasuda Swaminathan, John K. Olynyk
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
AimTo elucidate the role of mTOR inhibitors on iron, hepcidin and erythropoietin-mediated regulation of hemopoiesis in stable renal transplant recipients (RTR).BackgroundImpaired hemopoiesis is common following renal transplantation managed using mTO
Externí odkaz:
https://doaj.org/article/986b3bdcffa444998ce6e1ad318d90fa
Autor:
Justin Chin, Lawrie W. Powell, Louise E. Ramm, Oyekoya T. Ayonrinde, Grant A. Ramm, John K. Olynyk
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Development of advanced hepatic fibrosis in HFE Hemochromatosis (HH) is influenced by hepatic iron concentration (HIC) and age. In patients with HH, it is important to assess the likelihood of cirrhosis and thus the need for confirmatory liv
Externí odkaz:
https://doaj.org/article/7e028c4a0cd04c32b5358cebea354c79
Publikováno v:
Journal of Primary Care & Community Health, Vol 12 (2021)
Introduction/Objectives: Alcohol screening and brief intervention (ASBI) strategies are useful in general practice (GP) but their effectiveness in the emergency department (ED) is unclear. We evaluated the effect of ED-based ASBI on re-admissions. Me
Externí odkaz:
https://doaj.org/article/e929558d6cc04941b88cf526f636aae4
Autor:
Darrell H. G. Crawford, Grant A. Ramm, Kim R. Bridle, Amanda J. Nicoll, Martin B. Delatycki, John K. Olynyk
Publikováno v:
Hepatology International. 17:522-541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fda159c80aeca73c4787bf38f4f74fb
https://doi.org/10.1007/s12072-023-10510-3
https://doi.org/10.1007/s12072-023-10510-3