Zobrazeno 1 - 10
of 32
pro vyhledávání: '"John K Orak"'
Autor:
Ibrahim F Shatat, David J Taber, Sheetal Shrivastava, Nicole A Weimert, David J Sas, Kenneth D Chavin, John K Orak, Prabhakar K Baliga
Publikováno v:
Saudi Journal of Kidney Diseases and Transplantation, Vol 23, Iss 4, Pp 684-692 (2012)
While significant racial disparities in graft outcome persist among adult and pediatric kidney transplant recipients in the US, some international studies do not show these diffe-rences. The aim of this study is to examine predictors of graft outcome
Externí odkaz:
https://doaj.org/article/89b7751ae972482fa268882923db85b2
Autor:
John K. Orak, Ibrahim F. Shatat, Mary A. Johnson, Sherron M. Jakson, Ram Kalpatthi, Amanda E. Blue
Publikováno v:
Pediatric Nephrology. 28:115-120
The prevalence of hypertension and abnormal blood pressure (BP) patterns on 24-h ambulatory BP monitoring (ABPM) remains unknown in children with sickle cell disease (SCD).Thirty-eight asymptomatic children with sickle cell disease (SCD) (12 HbSS rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6843159ae272fefd7f2b7e531eed85db
https://doi.org/10.1007/s00467-012-2275-9
https://doi.org/10.1007/s00467-012-2275-9
Autor:
John K. Orak, Avtar K. Singh, Charanpal Sekhon, Kenneth Chavin, Inderjit Singh, Angello Lin, Bipanjeet Sekhon, Allyson Smith
Publikováno v:
Transplantation. 78:654-659
Background This study examined the potential therapeutic effects of a combination therapy consisting of 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside (AICAR) and N-acetyl cysteine (NAC) to attenuate ischemia-reperfusion (I/R) injury in a can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81c47ed935013badcc545f7e3c697b0
https://doi.org/10.1097/01.tp.0000131664.18670.17
https://doi.org/10.1097/01.tp.0000131664.18670.17
Publikováno v:
Molecular and Cellular Biochemistry. 240:9-17
Renal ischemia is of clinical interest because of its role in renal failure and also renal graft rejection. To evaluate the effect of the combination of N-acetylcysteine (NAC), a potent antioxidant, sodium nitroprusside (SNP), a nitric oxide donor, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b36f76a4469df7d59a1100de2b2d91
https://doi.org/10.1023/a:1020629020443
https://doi.org/10.1023/a:1020629020443
Publikováno v:
Molecular and Cellular Biochemistry. 240:19-29
Ischemia followed by reperfusion has a number of clinically significant consequences. A number of pathophysiological processes appear to be involved in ischemia/reperfusion (I/R) injury. The mitogen activated protein kinases (MAPK) are integral compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf75fe4d865c12e36ac23a85e27c5efa
https://doi.org/10.1023/a:1020675721351
https://doi.org/10.1023/a:1020675721351
Publikováno v:
Molecular and Cellular Biochemistry. 205:1-11
Reactive oxygen species (ROS; O2-, H2O2, and OH), normal by-products of cellular metabolic processes, are kept in control by antioxidant enzymes, such as catalase, glutathione peroxidase (GPX) and superoxide dismutases (SODs). To understand the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b345c9802f0c6f612854d22e80d86adf
https://doi.org/10.1023/a:1007047505107
https://doi.org/10.1023/a:1007047505107
Autor:
Kohtaro Asayama, Inderjit Singh, Kazushige Dobashi, Mahesh P. Gupta, Avtar K. Singh, John K. Orak
Publikováno v:
Molecular and Cellular Biochemistry. 197:7-12
By using highly purified peroxisomes from rat liver, we have shown that peroxisomes contain manganese superoxide dismutase (MnSOD) activity and a 23 kDa protein immunoreactive with antibodies against purified mitochondrial MnSOD. Immunocytochemical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2164444126905026f592fb5681b832d
https://doi.org/10.1023/a:1006848113499
https://doi.org/10.1023/a:1006848113499
Publikováno v:
Free Radical Biology and Medicine. 21:533-540
The effect of endotoxin on antioxidant gene expression and antioxidant enzyme activity in homogenates of the heart, liver, and kidney from Sprague-Dawley rats was compared by quantitation of m-RNA and enzyme activities. Alterations in the message lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c93b8ff02219872a0a74cd59819e02
https://doi.org/10.1016/0891-5849(96)00048-2
https://doi.org/10.1016/0891-5849(96)00048-2
Autor:
Prabhakar K Baliga, David James Taber, John K. Orak, Nicole A Weimert, Kenneth Chavin, Ibrahim F. Shatat, Sheetal Shrivastava, David J. Sas
Publikováno v:
Saudi Journal of Kidney Diseases and Transplantation, Vol 23, Iss 4, Pp 684-692 (2012)
While significant racial disparities in graft outcome persist among adult and pediatric kidney transplant recipients in the US, some international studies do not show these differences. The aim of this study is to examine predictors of graft outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4f7a53d9f9614111fe5e742f90b066
https://pubmed.ncbi.nlm.nih.gov/22805378
https://pubmed.ncbi.nlm.nih.gov/22805378
Autor:
Kohtaro Asayama, Gursev S. Dhaunsi, Inderjit Singh, John K. Orak, Anurag K. Singh, Mahesh P. Gupta
Publikováno v:
Archives of Biochemistry and Biophysics. 315:331-338
Earlier, we reported that rat liver peroxisomes contain Cu-Zn superoxide dismutase (J. Biol. Chem. 267, 6870), thereby suggesting a new antioxidant role for this organelle in free radical metabolism. In this study, we report for the first time that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d735ef1f603321ba8e6d9e0d18c466c
https://doi.org/10.1006/abbi.1994.1508
https://doi.org/10.1006/abbi.1994.1508