Zobrazeno 1 - 10
of 52
pro vyhledávání: '"John K, Pratt"'
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
High level of concomitant Bim and Bcl-2 expression correlates with sensitivity to ABBV-075-induced apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909cb57dd24aaafd2fca2c7e82f7b5b3
https://doi.org/10.1158/0008-5472.22414799.v1
https://doi.org/10.1158/0008-5472.22414799.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
Apoptosis induction by MS417 across cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae3d2859044504ae5d9fac2647897bd
https://doi.org/10.1158/0008-5472.22414754.v1
https://doi.org/10.1158/0008-5472.22414754.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
Restoration of Myc expression under BET inhibitor treatment failed to rescue cells from apoptosis or cell cycle arrest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abe11b9198b4334433eaf466eccee57
https://doi.org/10.1158/0008-5472.22414802
https://doi.org/10.1158/0008-5472.22414802
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
ABBV-075 is a potent and selective BET family bromodomain inhibitor that recently entered phase I clinical trials. Comprehensive preclinical characterization of ABBV-075 demonstrated broad activity across cell lines and tumor models, representing a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad920b8eb354003b6c1ac04c4521a267
https://doi.org/10.1158/0008-5472.c.6509072.v1
https://doi.org/10.1158/0008-5472.c.6509072.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
ABBV-075 inhibits Bcl-XL transcription and displace BRD4 from Bcl-XL regulatory regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc6edacd383875f0f6622459d88e551
https://doi.org/10.1158/0008-5472.22414808
https://doi.org/10.1158/0008-5472.22414808
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
Apoptosis induction by ABBV-075 across cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7803bc4645be2672355daa0a92ff36f7
https://doi.org/10.1158/0008-5472.22414757.v1
https://doi.org/10.1158/0008-5472.22414757.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
Induction of apoptosis across cancer cell lines and CD34 normal cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7deb1af53c0fc955ef7775ec54bc5c61
https://doi.org/10.1158/0008-5472.22414814.v1
https://doi.org/10.1158/0008-5472.22414814.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
Anti-proliferative activity of ABBV-075 across cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2367dbc73927b229f960f4aa97c7304b
https://doi.org/10.1158/0008-5472.22414763.v1
https://doi.org/10.1158/0008-5472.22414763.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
BET inhibitor causes cell cycle arrest and triggers senescence in solid tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117dc6645f8eb4c173a20cbe2dbc26af
https://doi.org/10.1158/0008-5472.22414778.v1
https://doi.org/10.1158/0008-5472.22414778.v1
Autor:
Yu Shen, Warren M. Kati, Keith F. McDaniel, Saul H. Rosenberg, Steven W. Elmore, Guowei Fang, Fred Kohlhapp, Xin Lu, Tamar Uziel, Lisa Hasvold, Dachun Liu, John K. Pratt, Steve Fidanze, Le Wang, George S. Sheppard, Cherrie K. Donawho, Denise Wilcox, Xiaoli Huang, Scott E. Warder, Emily J. Faivre, Lloyd T. Lam, Leiming Li, Daniel H. Albert, Xiaoyu Lin, Mai H. Bui
ABBV-075 inhibits hypoxia induced transcription of proangiogenesis factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec0b49b358dee22cb66a576dc9b4e2b
https://doi.org/10.1158/0008-5472.22414790
https://doi.org/10.1158/0008-5472.22414790