Zobrazeno 1 - 10
of 120
pro vyhledávání: '"John J. Vincent"'
Autor:
Nick Kamps-Hughes, Victoria E.H. Carlton, Laure Fresard, Steve Osazuwa, Elizabeth Starks, John J. Vincent, Sarah Albritton, Robert L. Nussbaum, Keith Nykamp
Publikováno v:
The Journal of Molecular Diagnostics. 25:156-167
Nearly 14% of disease-causing germline variants result from disruption of mRNA splicing. Most (67%) DNA variants predicted in silico to disrupt splicing end up classified as variants of uncertain significance (VUS). We developed and validated an anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b24bd42dfa60a429b74c1f5c2545f0
https://doi.org/10.1016/j.jmoldx.2022.12.002
https://doi.org/10.1016/j.jmoldx.2022.12.002
Autor:
AmirAli Talasaz, Darya I. Chudova, Richard B. Lanman, Helmy Eltoukhy, Cloud P. Paweletz, Lesli A. Kiedrowski, Christine E. Lee, Rebecca J. Nagy, Diana Abdueva, Reza Mokhtari, Marcin Sikora, Oliver A. Zill, Stephen R. Fairclough, Kimberly C. Banks, Bryan C. Ulrich, James V. Vowles, Stefanie Mortimer, John J. Vincent, Justin I. Odegaard
Empirical determination of the limit of detection. Defined oncogenic driver and background SNVs (a), oncogene and tumor suppressor indels (b), and oncogenic fusions (c) were titrated to specified VAFs, and multiple replicates were measured to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030f6711429f27f61a90cc50adfd7109
https://doi.org/10.1158/1078-0432.22469982.v1
https://doi.org/10.1158/1078-0432.22469982.v1
Autor:
AmirAli Talasaz, Darya I. Chudova, Richard B. Lanman, Helmy Eltoukhy, Cloud P. Paweletz, Lesli A. Kiedrowski, Christine E. Lee, Rebecca J. Nagy, Diana Abdueva, Reza Mokhtari, Marcin Sikora, Oliver A. Zill, Stephen R. Fairclough, Kimberly C. Banks, Bryan C. Ulrich, James V. Vowles, Stefanie Mortimer, John J. Vincent, Justin I. Odegaard
Digital Sequencing analytical performance metrics summary table.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd6fb602b6cf2e28bd4a930875bcf21
https://doi.org/10.1158/1078-0432.22469970
https://doi.org/10.1158/1078-0432.22469970
Autor:
AmirAli Talasaz, Darya I. Chudova, Richard B. Lanman, Helmy Eltoukhy, Cloud P. Paweletz, Lesli A. Kiedrowski, Christine E. Lee, Rebecca J. Nagy, Diana Abdueva, Reza Mokhtari, Marcin Sikora, Oliver A. Zill, Stephen R. Fairclough, Kimberly C. Banks, Bryan C. Ulrich, James V. Vowles, Stefanie Mortimer, John J. Vincent, Justin I. Odegaard
Purpose: To analytically and clinically validate a circulating cell-free tumor DNA sequencing test for comprehensive tumor genotyping and demonstrate its clinical feasibility.Experimental Design: Analytic validation was conducted according to establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a271108ee968afb99ee1b2fadd497511
https://doi.org/10.1158/1078-0432.c.6527406
https://doi.org/10.1158/1078-0432.c.6527406
Autor:
Elizabeth R. Starks, Victoria Carlton, Veena Rajaraman, Katya Kosheleva, Tamsen Dunn, Nick Kamps-Hughes, Laurie Gay, Meaghan Russell, Sarah Albritton, John J. Vincent, Nhu Ngo
Publikováno v:
Cancer Research. 82:1230-1230
Introduction: NGS-based tests that include biomarkers such as microsatellite instability (MSI) and tumor mutational burden (TMB) increase patient access to immune checkpoint inhibitors and improve the personalization of cancer care. Tumor-only NGS te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9611052022ea76b4e3394682253e8a41
https://doi.org/10.1158/1538-7445.am2022-1230
https://doi.org/10.1158/1538-7445.am2022-1230
Autor:
John J Vincent, Ziwei Li, Serena A Lee, Xian Liu, Marisabel O Etter, Silvia V Diaz-Perez, Sara K Taylor, Sofia Gkountela, Anne G Lindgren, Amander T Clark
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28960 (2011)
The cell intrinsic programming that regulates mammalian primordial germ cell (PGC) development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs) from mouse
Externí odkaz:
https://doaj.org/article/41385781e12541d0a8635b498f0d0413
Autor:
Anne G Lindgren, Kyle Natsuhara, E Tian, John J Vincent, Xinmin Li, Jing Jiao, Hong Wu, Utpal Banerjee, Amander T Clark
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16478 (2011)
Pluripotent stem cells (PSCs) hold significant promise in regenerative medicine due to their unlimited capacity for self-renewal and potential to differentiate into every cell type in the body. One major barrier to the use of PSCs is their potential
Externí odkaz:
https://doaj.org/article/a17551409f91412f850b8ebdb424141b
Autor:
Rebecca J. Nagy, John J. Vincent, Christine E. Lee, Bryan C. Ulrich, Stefanie Mortimer, Oliver A. Zill, Richard B. Lanman, Stephen R. Fairclough, Reza Bayat Mokhtari, James V. Vowles, Kimberly C. Banks, Justin I. Odegaard, AmirAli Talasaz, Diana Abdueva, Marcin Sikora, Cloud P. Paweletz, Darya Chudova, Helmy Eltoukhy, Lesli A. Kiedrowski
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(15)
Purpose: To analytically and clinically validate a circulating cell-free tumor DNA sequencing test for comprehensive tumor genotyping and demonstrate its clinical feasibility. Experimental Design: Analytic validation was conducted according to establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be604fbae674d4ca9da63cbf18a1dba3
https://pubmed.ncbi.nlm.nih.gov/29691297
https://pubmed.ncbi.nlm.nih.gov/29691297
Autor:
John J. Vincent
Publikováno v:
The Expository Times. 125:117-122
The practice of an experimental Christian café-centre in inner city Sheffield provokes reprise with Mark’s multi-faith and multicultural narratives. The dramatis personae, the street-level exposées, and the cultural clashes of Mark 5 evoke sponta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663f63326bbe5202d253335c3812a57a
https://doi.org/10.1177/0014524613479873
https://doi.org/10.1177/0014524613479873