Zobrazeno 1 - 10
of 146
pro vyhledávání: '"John J. Skinner"'
Autor:
Chris Gessner, Wieland Steinchen, Sabrina Bédard, John J. Skinner, Virgil L. Woods, Thomas J. Walsh, Gert Bange, Dionysios P. Pantazatos
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Hydrogen-deuterium exchange (HDX) coupled with mass spectrometry (HDXMS) is a rapid and effective method for localizing and determining protein stability and dynamics. Localization is routinely limited to a peptide resolution of 5 to 20 amin
Externí odkaz:
https://doaj.org/article/a71050ed12c6431e8c2981c692e1ae08
Autor:
Xuechen Lv, Junlin Liu, Qiaoyun Shi, Qiwen Tan, Dong Wu, John J. Skinner, Angela L. Walker, Lixia Zhao, Xiangxiang Gu, Na Chen, Lu Xue, Pei Si, Lu Zhang, Zeshi Wang, Vsevolod Katritch, Zhi-jie Liu, Raymond C. Stevens
Publikováno v:
Protein & Cell, Vol 7, Iss 5, Pp 325-337 (2016)
ABSTRACT G protein-coupled receptors (GPCRs) are involved in all human physiological systems where they are responsible for transducing extracellular signals into cells. GPCRs signal in response to a diverse array of stimuli including light, hormones
Externí odkaz:
https://doaj.org/article/3b06f28f97cb418fab009f75e341d565
Autor:
Xin Wang, Yan Li, Meng Sun, Jiping Zha, Songmao Zheng, Guizhong Liu, Peter Luo, John J Skinner, Kristine She, Jiangchun Xu, Felix Du
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/54d3ae910a7e49a8b32d88e170c68136
Publikováno v:
Analytical Chemistry. 91:7474-7481
Hydrogen-deuterium exchange mass spectrometry (HDX MS) has become an important technique for the analysis of protein structure and dynamics. Data analysis remains a bottleneck in the workflow. Sophisticated computer analysis is required to scan throu
Autor:
Virgil L. Woods, Sabrina Bédard, Wieland Steinchen, Gert Bange, Thomas J. Walsh, John J. Skinner, Chris Gessner, Dennis Pantazatos
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Hydrogen-deuterium exchange (HDX) coupled with mass spectrometry (HDXMS) is a rapid and effective method for localizing and determining protein stability and dynamics. Localization is routinely limited to a peptide resolution of 5 to 20 amino acid re
Autor:
Lu Zhang, John J. Skinner, Na Chen, Vsevolod Katritch, Dong Wu, Angela L. Walker, Junlin Liu, Qiaoyun Shi, Raymond C. Stevens, Lu Xue, Zeshi Wang, Pei Si, Xuechen Lv, Lixia Zhao, Zhi-Jie Liu, Xiangxiang Gu, Qiwen Tan
Publikováno v:
Protein & Cell
Protein & Cell, Vol 7, Iss 5, Pp 325-337 (2016)
Protein & Cell, Vol 7, Iss 5, Pp 325-337 (2016)
G protein-coupled receptors (GPCRs) are involved in all human physiological systems where they are responsible for transducing extracellular signals into cells. GPCRs signal in response to a diverse array of stimuli including light, hormones, and lip
Autor:
Kristina Lorenz, Caroline Kisker, Sivaraj Sivaramakrishnan, Maria Hirschbeck, Colin Ong, John J. Skinner, Sheng Wang, Marsha Rich Rosner, Ruth F. Sommese, W. Koelmel, Jiyoung Lee, Tobin R. Sosnick, Hermann Schindelin
Publikováno v:
The FASEB Journal. 32
Phosphorylation is a major regulator of protein interactions; however, the mechanisms by which regulation occurs are not well understood. Here we identify a salt-bridge competition or “theft” mechanism that enables a phospho-triggered swap of pro
Publikováno v:
Journal of Biomolecular NMR, 68 (1)
The amino acid 4-fluoro-l-phenylalanine (4F-Phe) was introduced at the positions of Phe6 and Phe22 in the 29-residue polypeptide hormone glucagon by expressing glucagon in E. coli in the presence of an excess of 4F-Phe. Glucagon regulates blood gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f02b1a749119ad5c4f0af12244c549c
https://hdl.handle.net/20.500.11850/209581
https://hdl.handle.net/20.500.11850/209581
Publikováno v:
Journal of Biomolecular Nmr
The amino acid 4-fluoro-l-phenylalanine (4F-Phe) was introduced at the positions of Phe6 and Phe22 in the 29-residue polypeptide hormone glucagon by expressing glucagon in E. coli in the presence of an excess of 4F-Phe. Glucagon regulates blood gluco
Autor:
Hermann Schindelin, Jiyoung Lee, Marsha Rich Rosner, Caroline Kisker, Ruth F. Sommese, W. Koelmel, Kristina Lorenz, Tobin R. Sosnick, Sivaraj Sivaramakrishnan, Sheng Wang, John J. Skinner, Maria Hirschbeck, Colin Ong
Phosphorylation is a major regulator of protein interactions; however, the mechanisms by which regulation occurs are not well understood. Here we identify a salt-bridge competition or “theft” mechanism that enables a phospho-triggered swap of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f2f00d736d4aeb740bdce9fd6f7044
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85038844775
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85038844775