Zobrazeno 1 - 7
of 7
pro vyhledávání: '"John J. Roderick"'
Autor:
Chu-Biao Xue, John Wityak, Thais M. Sielecki, Donald J. Pinto, Douglas G. Batt, Gary A. Cain, Michael Sworin, Arlene L. Rockwell, John J. Roderick, Shuaige Wang, Michael J. Orwat, William E. Frietze, Lori L. Bostrom, Jie Liu, C. Anne Higley, F. Wayne Rankin, A. Ewa Tobin, George Emmett, George K. Lalka, Jean Y. Sze, Susan V. Di Meo, Shaker A. Mousa, Martin J. Thoolen, Adrienne L. Racanelli, Elizabeth A. Hausner, Thomas M. Reilly, William F. DeGrado, Ruth R. Wexler, Richard E. Olson
Publikováno v:
Journal of Medicinal Chemistry. 40:2064-2084
Using isoxazoline XR299 (1a) as a starting point for the design of highly potent, long-duration GPIIb/IIIa antagonists, the effect of placing lipophilic substituents at positions alpha and beta to the carboxylate moiety was evaluated. Of the compound
Autor:
Sheppeck JE 2nd; Bristol-Myers Squibb Pharmaceutical Research Institute, Discovery Chemistry, PO Box 4000, Princeton, NJ 08543-4000, USA. jim.sheppeck@bms.com, Gilmore JL, Yang A, Chen XT, Xue CB, Roderick J, Liu RQ, Covington MB, Decicco CP, Duan JJ
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Mar 01; Vol. 17 (5), pp. 1413-7. Date of Electronic Publication: 2006 Dec 02.
Autor:
Batt DG; dBristol-Myers Squibb, Pharmaceutical Research Institute, PO Box 4000, Princeton, NJ 08543-4000, USA. douglas.batt@bms.com, Houghton GC, Roderick J, Santella JB 3rd, Wacker DA, Welch PK, Orlovsky YI, Wadman EA, Trzaskos JM, Davies P, Decicco CP, Carter PH
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2005 Feb 01; Vol. 15 (3), pp. 787-91.
Autor:
Xue CB; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000, USA. cxue@incyte.com, Chen XT, He X, Roderick J, Corbett RL, Ghavimi B, Liu RQ, Covington MB, Qian M, Ribadeneira MD, Vaddi K, Trzaskos J, Newton RC, Duan JJ, Decicco CP
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2004 Sep 06; Vol. 14 (17), pp. 4453-9.
Autor:
Xue CB; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000, USA. cxue@incite.com, He X, Roderick J, Corbett RL, Duan JJ, Liu RQ, Covington MB, Qian M, Ribadeneira MD, Vaddi K, Christ DD, Newton RC, Trzaskos JM, Magolda RL, Wexler RR, Decicco CP
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2003 Dec 15; Vol. 13 (24), pp. 4299-304.
Autor:
Xue CB; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000, USA. cxue@incyte.com, He X, Roderick J, Corbett RL, Duan JJ, Liu RQ, Covington MB, Newton RC, Trzaskos JM, Magolda RL, Wexler RR, Decicco CP
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2003 Dec 15; Vol. 13 (24), pp. 4293-7.
Autor:
Xue CB; Chemical and Physical Sciences, DuPont Pharmaceuticals Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880, USA. chu-biao.xue@dupontpharma.com, He X, Roderick J, Corbett RL, Decicco CP
Publikováno v:
The Journal of organic chemistry [J Org Chem] 2002 Feb 08; Vol. 67 (3), pp. 865-70.