Zobrazeno 1 - 10
of 493
pro vyhledávání: '"John J. McCarthy"'
Autor:
John J. McCarthy, Loretta P. Finnegan
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Since the first use of methadone to treat OUD in pregnancy in the 1970s, there has been a long, controversial, and confusing history of studies, regulatory actions, and practice changes that have clouded an accurate perception of methadone's use in p
Externí odkaz:
https://doaj.org/article/a576487f648c42f6aba7ba5dfdd664db
Autor:
Benjamin I. Burke, Jensen Goh, Fatmah A. Albathi, Taylor R. Valentino, Georgia L. Nolt, Jai K. Joshi, Cory M. Dungan, Lance A. Johnson, Yuan Wen, Ahmed Ismaeel, John J. McCarthy
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Apolipoprotein E (ApoE) has been shown to be necessary for proper skeletal muscle regeneration. Consistent with this finding, single-cell RNA-sequencing analyses of skeletal muscle stem cells (MuSCs) revealed that Apoe is a top marker o
Externí odkaz:
https://doaj.org/article/fe9f970a147c4232b8eacab89dcc655a
Autor:
Ahmed Ismaeel, Taylor R. Valentino, Benjamin Burke, Jensen Goh, Tolulope P. Saliu, Fatmah Albathi, Allison Owen, John J. McCarthy, Yuan Wen
Publikováno v:
Physiological Reports, Vol 11, Iss 21, Pp n/a-n/a (2023)
Abstract Recently, the gut microbiome has emerged as a potent modulator of exercise‐induced systemic adaptation and appears to be crucial for mediating some of the benefits of exercise. This study builds upon previous evidence establishing a gut mi
Externí odkaz:
https://doaj.org/article/eaa76897c15747e79d797f4010157bc2
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 5, Pp 2276-2297 (2022)
Abstract One aspect of skeletal muscle memory is the ability of a previously trained muscle to hypertrophy more rapidly following a period of detraining. Although the molecular basis of muscle memory remains to be fully elucidated, one potential mech
Externí odkaz:
https://doaj.org/article/d3820f7622dd4d38b9ec01d6c156e508
Autor:
Vandré C. Figueiredo, Randall F. D'Souza, Douglas W. Van Pelt, Marcus M. Lawrence, Nina Zeng, James F. Markworth, Sally D. Poppitt, Benjamin F. Miller, Cameron J. Mitchell, John J. McCarthy, Esther E. Dupont‐Versteegden, David Cameron‐Smith
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 130-143 (2021)
Abstract Background Translational capacity (i.e. ribosomal mass) is a key determinant of protein synthesis and has been associated with skeletal muscle hypertrophy. The role of translational capacity in muscle atrophy and regrowth from disuse is larg
Externí odkaz:
https://doaj.org/article/738d05f29a7246dfb04060da7a14eb4e
Autor:
Ferdinand Von Walden, Matthew Rea, C. Brooks Mobley, Yvonne Fondufe-Mittendorf, John J. McCarthy, Charlotte A. Peterson, Kevin A. Murach
Publikováno v:
Epigenetics, Vol 15, Iss 11, Pp 1151-1162 (2020)
In addition to multi-nucleated muscle fibres, numerous resident and infiltrating mononuclear cells populate the muscle compartment. As most epigenetic assays in skeletal muscle are conducted on whole tissue homogenates, essentially nothing is known a
Externí odkaz:
https://doaj.org/article/fb0b9f0b52af4ab79fa2fe8f59fd6409
Autor:
Taylor Valentino, Vandre C. Figueiredo, C. Brooks Mobley, John J. McCarthy, Ivan J. Vechetti Jr
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Many of the molecular and cellular mechanisms discovered to regulate skeletal muscle hypertrophy were first identified using the rodent synergist ablation model. This model reveals the intrinsic capability and necessary pathways of skeletal
Externí odkaz:
https://doaj.org/article/c96b1693a8814069b28666f54aaf6fd4
Autor:
Yuan Wen, Davis A. Englund, Bailey D. Peck, Kevin A. Murach, John J. McCarthy, Charlotte A. Peterson
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102838- (2021)
Summary: Skeletal muscle is composed of post-mitotic myofibers that form a syncytium containing hundreds of myonuclei. Using a progressive exercise training model in the mouse and single nucleus RNA-sequencing (snRNA-seq) for high-resolution characte
Externí odkaz:
https://doaj.org/article/943dd826db33413cb54063aae105fce2
Autor:
Kevin A. Murach, Bailey D. Peck, Robert A. Policastro, Ivan J. Vechetti, Douglas W. Van Pelt, Cory M. Dungan, Lance T. Denes, Xu Fu, Camille R. Brightwell, Gabriel E. Zentner, Esther E. Dupont-Versteegden, Christopher I. Richards, Jeramiah J. Smith, Christopher S. Fry, John J. McCarthy, Charlotte A. Peterson
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102372- (2021)
Summary: Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking, satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show satellite cells communicate with other cells in skeletal m
Externí odkaz:
https://doaj.org/article/bf5d536bcc1c44ae96a88fbbda14f370
A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression
Autor:
Masahiro Iwata, Davis A. Englund, Yuan Wen, Cory M. Dungan, Kevin A. Murach, Ivan J. Vechetti, Christopher B. Mobley, Charlotte A. Peterson, John J. McCarthy
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Background The tetracycline-responsive system (Tet-ON/OFF) has proven to be a valuable tool for manipulating gene expression in an inducible, temporal, and tissue-specific manner. The purpose of this study was to create and characterize a ne
Externí odkaz:
https://doaj.org/article/d7c9b283fa8b40d48bc49dd7646f3dfa