Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John J. M. Bouwman"'
Autor:
Teske Schoffelen, Gijs J M Limonard, Chantal P Bleeker-Rovers, John J M Bouwman, Jos W M van der Meer, Marrigje Nabuurs-Franssen, Tom Sprong, Marcel van Deuren
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103749 (2014)
Diagnosis of ongoing or past infection with Coxiella burnetii, the causative agent of Q fever, relies heavily on serology: the measurement of C. burnetii-specific antibodies, reflecting the host's humoral immune response. However, cell-mediated immun
Externí odkaz:
https://doaj.org/article/4fab210827f3460a9c518552b8de4680
Autor:
Daan W. Notermans, M. Salomons, Steven F. T. Thijsen, Bart J. M. Vlaminckx, T. van Gorkom, R. H. Muilwijk, Kristin Kremer, Sanjay U. C. Sankatsing, D. M. Ismail, W. Voet, Aik Bossink, John J. M. Bouwman
Publikováno v:
Journal of Clinical Microbiology
Two-tier serology testing is most frequently used for the diagnosis of Lyme borreliosis (LB); however, a positive result is no proof of active disease. To establish a diagnosis of active LB, better diagnostics are needed. Tests investigating the cell
Publikováno v:
FEMS Immunology & Medical Microbiology. 64:57-60
Definitively establishing a clinical diagnosis of chronic Q fever remains challenging, as the diagnostic performance of both conventional serological tests and PCR is limited. Given the importance of an early diagnosis of chronic Q fever, there is a
Publikováno v:
Clinical and Vaccine Immunology. 16:1222-1227
Obesity is associated with a chronic inflammatory state, and adipocyte dysfunction is thought to play a crucial role in this. Infection of adipose tissue may trigger the production of inflammatory cytokines, leading to increased recruitment of macrop
Publikováno v:
International Journal of Obesity. 32:892-901
Abdominal obesity plays an important role in the development of insulin resistance, diabetes mellitus and atherosclerosis. The exact pathophysiological mechanisms are unclear but adipocyte dysfunction is thought to be crucial. Infections are associat
Autor:
W. E. Van Der Vlist, L. M. Bevers, R. J. A. Diepersloot, Frank L.J. Visseren, John J. M. Bouwman, K.P. Bouter
Publikováno v:
European Journal of Clinical Investigation. 35:573-582
Intracellular infections with cytomegalovirus (CMV) or Chlamydia pneumoniae (Cp) may play a role in the aetiology of atherosclerosis. Nitric oxide (NO) is a key regulator of endothelial function. Under pathological conditions uncoupling of endothelia
Publikováno v:
European Journal of Clinical Investigation. 32:759-766
Background Monocytes play a prominent role in inflammation, coagulation and atherosclerosis by their ability to produce tissue factor (TF) and cytokines. The aim of the present study was to establish whether virus-infected monocytes initiate coagulat
Autor:
John J. M. Bouwman, de Groot Ph, Erkelens Dw, Frank L.J. Visseren, K.P. Bouter, R. J. A. Diepersloot
Publikováno v:
Thrombosis and Haemostasis. 84:319-324
SummaryInfluenza virus epidemics are associated with excess mortality due to cardiovascular diseases. There are several case reports of excessive coagulation during generalised influenza virus infection. In this study, we demonstrate the ability of r
Autor:
Ailko W. J. Bossink, Roan Spermon, John J. M. Bouwman, Karen A. Heemstra, Robert van der Kieft, Steven F. T. Thijsen
In this case series, we describe four cases in which the use of gamma interferon release assays with purified protein derivative (PPD) as a stimulating antigen was able to demonstrate PPD-specific immune activation. This may help to improve the adequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b04630b17ac6215b94b60b733a4a8d
https://europepmc.org/articles/PMC3370454/
https://europepmc.org/articles/PMC3370454/
Publikováno v:
FEMS immunology and medical microbiology. 64(1)
Definitively establishing a clinical diagnosis of chronic Q fever remains challenging, as the diagnostic performance of both conventional serological tests and PCR is limited. Given the importance of an early diagnosis of chronic Q fever, there is a