Zobrazeno 1 - 10
of 57
pro vyhledávání: '"John J. Long"'
Autor:
Hongjian Qi, Haicang Zhang, Yige Zhao, Chen Chen, John J. Long, Wendy K. Chung, Yongtao Guan, Yufeng Shen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Accurate prediction of variant pathogenicity is essential to understanding genetic risks in disease. Here, the authors present a deep neural network method for prediction of missense variant pathogenicity, MVP, and demonstrate its utility in prioriti
Externí odkaz:
https://doaj.org/article/00b2a98c75c843c688e0cc486648e40e
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Rhizoctonia solani is a soil-borne fungal pathogen of many important crop plants. In rice, R. solani causes sheath blight disease, which results in devastating grain yield and quality losses. Few methods are available to control th
Externí odkaz:
https://doaj.org/article/9d688175798d47a7a52ab78749236d92
Autor:
Teja Shidore, Corey D Broeckling, Jay S Kirkwood, John J Long, Jiamin Miao, Bingyu Zhao, Jan E Leach, Lindsay R Triplett
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006442 (2017)
Gram-negative bacterial pathogens of plants and animals employ type III secreted effectors to suppress innate immunity. Most characterized effectors work through modification of host proteins or transcriptional regulators, although a few are known to
Externí odkaz:
https://doaj.org/article/bd9c193462c449298d493f6fccd018f6
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
BMC Research Notes
BMC Research Notes
Objective Rhizoctonia solani is a soil-borne fungal pathogen of many important crop plants. In rice, R. solani causes sheath blight disease, which results in devastating grain yield and quality losses. Few methods are available to control this pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a475c8bdd8aa8a1b93730c839148a88
http://link.springer.com/article/10.1186/s13104-019-4802-2
http://link.springer.com/article/10.1186/s13104-019-4802-2
Autor:
Yige Zhao, Yongtao Guan, John J. Long, Wendy K. Chung, Chen Chen, Haicang Zhang, Hongjian Qi, Yufeng Shen
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Accurate pathogenicity prediction of missense variants is critically important in genetic studies and clinical diagnosis. Previously published prediction methods have facilitated the interpretation of missense variants but have limited performance. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e4e2804cb04d5010ba5770b0b5d3ac
https://doi.org/10.1038/s41467-020-20847-0
https://doi.org/10.1038/s41467-020-20847-0
Autor:
Andrea Sanchez-Hidalgo, William H. Wheat, Mercedes Gonzalez-Juarrero, Jan E. Leach, Mary Jackson, Courtney E. Jahn, John J. Long
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202941 (2018)
Background Free-living amoebae (FLA) are voracious feeders, consuming bacteria and other microbes during colonization of the phytobiome. FLA are also known to secrete bacteriocidal or bacteriostatic compounds into their growth environment. Methodolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3261839709b8380018c144757a8a73d8
https://pubmed.ncbi.nlm.nih.gov/30142182
https://pubmed.ncbi.nlm.nih.gov/30142182
Autor:
Yufeng Shen, Haicang Zhang, Yongtao Guan, Hongjian Qi, John J. Long, Wendy K. Chung, Chen Chen
Accurate pathogenicity prediction of missense variants is critical to improve power in genetic studies and accurate interpretation in clinical genetic testing. Here we describe a new prediction method, MVP, which uses a deep learning approach to leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3953f72dacf1bf6c8c24886988a0f660
Autor:
Jay S. Kirkwood, Bingyu Zhao, Jan E. Leach, Teja Shidore, Jiamin Miao, Lindsay R. Triplett, Corey D. Broeckling, John J. Long
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006442 (2017)
PLoS Pathogens
PLoS Pathogens
Gram-negative bacterial pathogens of plants and animals employ type III secreted effectors to suppress innate immunity. Most characterized effectors work through modification of host proteins or transcriptional regulators, although a few are known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01629b7b2fe970f3f069a5ba995f22c2
http://europepmc.org/articles/PMC5491322?pdf=render
http://europepmc.org/articles/PMC5491322?pdf=render
Publikováno v:
XSEDE
Authentication for HPC resources has always been a double edged issue. On one hand, HPC facilities would like users to login as easily as possible, but with the increase and complexity of system exploits, HPC centers would like to protect their syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df59aea51d6221ef1b829d0313391e15
https://doi.org/10.1145/2949550.2949559
https://doi.org/10.1145/2949550.2949559
Autor:
Hiromichi Ishihara, Qian Han, Lindsay R. Triplett, Jianyong Li, Bingyu Zhao, Jan E. Leach, Jiamin Miao, Shuchi Wu, John J. Long, Teja Shidore, Changhe Zhou
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158856 (2016)
PLoS ONE
PLoS ONE
Toxin-antitoxin (TA) systems are ubiquitous bacterial systems that may function in genome maintenance and metabolic stress management, but are also thought to play a role in virulence by helping pathogens survive stress. We previously demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d19fd17fe0d818f3404d583dfdf67dc
http://europepmc.org/articles/PMC4938570?pdf=render
http://europepmc.org/articles/PMC4938570?pdf=render