Zobrazeno 1 - 10
of 12
pro vyhledávání: '"John J. Jessop"'
Autor:
Syed N. Alam, John J. Jessop, Adorjan Aszalos, Kenneth L. Hastings, Chang-Ho Ahn, Young S. Choi, James L. Weaver
Publikováno v:
Drug Information Journal. 31:1357-1361
Determination of the potential for an investigational drug to adversely affect the immune system is a standard component of nonclinical toxicology studies. Potential adverse immune effects include ...
Publikováno v:
Inflammation. 17(5)
LPS stimulation of human monocytes in vitro induced release of the 17-kDa mature IL-1 beta (mIL-1 beta) but did not result in release of precursor IL-1 beta (pIL-1 beta). In contrast, the presence of a serine protease inhibitor, N alpha-(p-toluene su
Autor:
John J. Jessop, Michael Taplits
Publikováno v:
Immunopharmacology. 22(3)
Morphine, a potent analgesic drug as well as the active metabolite derived from heroin, has been reported to affect a variety of immune functions. In vivo administration of high doses of morphine to animals has been shown to inhibit natural killer (N
Autor:
Young Lim Lee, Thomas Hoffman, Elaine F. Lizzio, Tore G. Abrahamsen, Joseph Puri, John J. Jessop, Michael Taplits, Charles S. Carter, Anil K. Tripathi
Publikováno v:
Clinical immunology and immunopathology. 58(3)
Human peripheral blood monocytes exposed to MK-886 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2- dimethylpropanoic acid) at doses which abolish formation of 5-lipoxygenase metabolites showed unaltered interleukin-1 beta (IL-1 beta
Autor:
John J. Jessop, Michael S. Taplits
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468459272
Opiate addicts are often exposed to doses of exogenous opiates as high as 2 grams of heroin per day (1). Opiates also concentrate in the spleen, thus exposing the cells of the immune system in addicts to high concentrations of these drugs (2). As a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec170ef5c5cf214060a0bf6db0e8472
https://doi.org/10.1007/978-1-4684-5925-8_20
https://doi.org/10.1007/978-1-4684-5925-8_20
Publikováno v:
Biochemistry. 17:1143-1149
Autor:
Barbara M. Bayer, John J. Jessop
Publikováno v:
Journal of Neuroimmunology. 23:143-147
• Individual housing of previously group-based animals was fund to result in time-dependent changes in mitogen-induced lymphocyte proliferation and plasma corticosterone concentrations. During the first week of isolation, both B and T lymphocyte re
Publikováno v:
Biochemistry. 17:1149-1153
Publikováno v:
Toxicology and industrial health. 3(1)
Triphenyl phosphate (TPP), a potential food contaminant, was fed to weanling Spartan Sprague-Dawley rats at dose levels of 0, 0.25, 0.5, 0.75, and 1.0%for 120 days. The immunotoxicity evaluation, planned as a minimum testing model in a subchronic stu
Publikováno v:
Journal of neuroimmunology. 16(2)
Rats exposed to 5 weeks of isolation, water scheduling (daily consumption restricted to 30 min), and their combination demonstrated significantly enhanced splenic lymphocyte proliferative responses to phytohemagglutinin (PHA) compared to those of gro