Zobrazeno 1 - 10
of 146
pro vyhledávání: '"John J. Hablitz"'
Autor:
Kazuhito Nakao, Mahendra Singh, Kiran Sapkota, Andrew Fitzgerald, John J. Hablitz, Kazu Nakazawa
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Blockade of N-methyl-D-aspartate receptors (NMDAR) is known to augment cortical serotonin 2A receptors (5-HT2ARs), which is implicated in psychosis. However, the pathways from NMDAR hypofunction to 5-HT2AR up-regulation are unclear. Here we
Externí odkaz:
https://doaj.org/article/f7125f551a1941f98b146a6fb1f9b851
Autor:
Andrew S. Bohannon, John J. Hablitz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Layer 1 (L1) interneurons (INs) play a key role in modulating the integration of inputs to pyramidal neurons (PNs) and controlling cortical network activity. Hyperpolarization-activated, cyclic nucleotide-gated, non-specific cation (HCN) channels are
Externí odkaz:
https://doaj.org/article/b28d74d489a846c7b917a23f98faf0af
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Cortical malformations are often associated with pharmaco-resistant epilepsy. Alterations in hyperpolarization-activated, cyclic nucleotide-gated, non-specific cation (HCN) channels have been shown to contribute to malformation associated hyperexcita
Externí odkaz:
https://doaj.org/article/a0f72745555d4d04836bb5303518a7b3
Autor:
Susan L. Campbell, John J. Hablitz
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 2, Pp 254-261 (2008)
Glutamate transporters function to maintain low levels of extracellular glutamate and play an important role in synaptic transmission at many synapses. Disruption of glutamate transporter function or expression can result in increased extracellular g
Externí odkaz:
https://doaj.org/article/7ae843a6ebe44143990574d77317d2d8
Autor:
Mahendra Singh, Kiran Sapkota, Kenji Sakimura, Masanobu Kano, Rita M Cowell, Linda Overstreet-Wadiche, John J Hablitz, Kazu Nakazawa
Publikováno v:
Neuroscience. 513:38-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff131dc378a4109e86e27840f1f63292
https://doi.org/10.1016/j.neuroscience.2023.01.007
https://doi.org/10.1016/j.neuroscience.2023.01.007
Autor:
Daniel K. Mulkey, Alexander Staruschenko, Christopher M. Gonçalves, Michelle L. Olsen, John J. Hablitz, Kelsey C. Patterson, Uri Kahanovitch
Publikováno v:
Glia. 69:310-325
Astrocyte heterogeneity is an emerging concept in which astrocytes within or between brain regions show variable morphological and/or gene expression profiles that presumably reflect different functional roles. Recent evidence indicates that retrotra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::136c751d77f1243dfca511df0f0a18dd
https://doi.org/10.1002/glia.23898
https://doi.org/10.1002/glia.23898
Autor:
Kazuhito Nakao, Bailey C Hagler, Chander Raman, John J. Hablitz, Robert N. Hunter, Kiran Sapkota, Kazu Nakazawa, Mahendra Singh
Publikováno v:
Neuropsychopharmacology
Cortical gamma oscillations are believed to be involved in mental processes which are disturbed in schizophrenia. For example, the magnitudes of sensory-evoked oscillations, as measured by auditory steady-state responses (ASSRs) at 40 Hz, are robustl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576ea6c9b08b0d6128402823e63ed376
http://europepmc.org/articles/PMC7784891
http://europepmc.org/articles/PMC7784891
Autor:
Aundrea F. Bartley, Elena W Adlaf, Andrew S. Bohannon, Peter J. Detloff, David K. Crossman, T. van Groen, Linda Overstreet-Wadiche, Laura J. McMeekin, Lynn E. Dobrunz, Rita M. Cowell, John J. Hablitz, Stephanie N. Fox, S.M. Boas
Publikováno v:
Neuroscience
The transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a critical regulator of genes involved in neuronal metabolism, neurotransmission, and morphology. Reduced PGC-1α expression has been implicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a2266e981769b1cfc0f5436ca16656
https://doi.org/10.1016/j.neuroscience.2020.03.036
https://doi.org/10.1016/j.neuroscience.2020.03.036
Autor:
Mahendra Singh, Kiran Sapkota, Kenji Sakimura, Masanobu Kano, Rita M. Cowell, Linda O. Wadiche, John J. Hablitz, Kazutoshi Nakazawa
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e8d92e33196df62c82b4a94057f0517
https://doi.org/10.2139/ssrn.4170636
https://doi.org/10.2139/ssrn.4170636
Publikováno v:
Epilepsy Research. 183:106937
4-Aminopyridine (4-AP) induces ictal-like epileptiform discharges in a variety of brain regions. These events are associated with enhanced inhibitory and excitatory synaptic neurotransmission. The relative contribution of specific subclasses of GABAe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aa26fc71f1719224eeb65d512942e1
https://doi.org/10.1016/j.eplepsyres.2022.106937
https://doi.org/10.1016/j.eplepsyres.2022.106937