Výsledky vyhledávání - "John J. Gullo"

A prospective randomized comparison of protracted infusional 5-fluorouracil with or without weekly bolus cisplatin in metastatic colorectal carcinoma. A mid-atlantic oncology program study

Autor: Diane E. Alt, Jacob J. Lokich, James Cantrell, John G. Fryer, James D. Ahlgren, Galen L. Wampler, William J. Heim, John J. Gullo

Publikováno v: Cancer. 67:14-19

One hundred eighty-four patients with advanced measurable colorectal cancer not previously treated with chemotherapy were entered into a prospective randomized clinical trial by the Mid-Atlantic Oncology Program (MAOP) to assess the value of weekly c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::336088f0e876c69bbdd5ffe87ffc119b
https://doi.org/10.1002/1097-0142(19910101)67:1<14::aid-cncr2820670104>3.0.co

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Randomized clinical trial of mitomycin-C with or without pretreatment with WR-2721 in patients with advanced colorectal cancer

Autor: Elizabeth Poplin, William McCulloch, Joseph J. Schulz, Laurence H. Baker, John J. Gullo, Jacob J. Lokich, Philip D. Leming, Stephen R. Veach, Philip Schein, Patricia LoRusso

Publikováno v: Cancer chemotherapy and pharmacology. 33(5)

The use of mitomycin for metastatic colorectal cancer has been limited by mitomycin's myelosuppressive potential. The objective of this randomized study was to determine whether WR-2721 would decrease the hematologic toxicity of mitomycin in patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b12dc8f20d227f98b008d189cb87ad
https://pubmed.ncbi.nlm.nih.gov/8306416

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Dichloromethotrexate, infusional cisplatin, and infusional 5-fluorouracil for locally advanced or metastatic non-small cell lung cancer. A MAOP study

Autor: John J. Gullo, Jacob J. Lokich, Galen L. Wampler, James A. Phillips, James D. Ahlgren

Publikováno v: American journal of clinical oncology. 14(5)

The combination of dichloromethotrexate, cisplatin, and infusional 5-fluorouracil was evaluated as treatment for non-small-cell lung cancer in a phase II trial using 43 evaluable patients. Grade III or IV toxicity included thrombocytopenia (21%), leu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2cc2df4075a48ac2f21f88cd76ff35
https://pubmed.ncbi.nlm.nih.gov/1659178

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Protracted infusion of 5-FU with weekly low-dose cisplatin as second-line therapy in patients with metastatic colorectal cancer who have failed 5-FU monotherapy

Autor: Regina Sisk, W. Angus Muir, Orrawin Trocki, James D. Ahlgren, Lee P. Schacter, John J. Gullo, Richard M. Goldberg

Publikováno v: Cancer investigation. 9(1)

Forty four patients who had documented progression of metastatic colorectal cancer while receiving 5-fluorouracil (5-FU) monotherapy were treated with continuous infusion 5-FU, 300 mg/mg2/day, plus weekly low-dose cisplatin, 20 mg/m2. Treatment was g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0b9fe0775080778bfc00d043fd609f
https://pubmed.ncbi.nlm.nih.gov/2012994

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Histologic alterations in small cell carcinoma of the lung after two cycles of intensive chemotherapy

Autor: Frederick B. Parker, Phillip M. Ikins, Robert L. Comis, William A. Burke, Santo M. DiFino, John J. Gullo, John A. Meyer

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 87:283-290

In patients treated nonsurgically for "limited" small cell carcinoma of the lung, the most frequent site of relapse is within the chest. We have treated patients with clinical Stage III M0 disease (T3 and/or N2, M0) by two cycles of chemotherapy, sur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8c524696bdde4767e2025164ca784af
https://doi.org/10.1016/s0022-5223(19)37423-9

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Pharmacokinetics and protein binding of cis-dichlorodiammine platinum (II) administered as a one hour or as a twenty hour infusion

Autor: Paul V. Woolley, Patrick J. Maguire, Branimir I. Sikic, Charles L. Litterst, John J. Gullo, Daniel Hoth

Publikováno v: Cancer Chemotherapy and Pharmacology. 5:21-26

The pharmacokinetics of cis-dichlorodiam-minoplatinum (II) (cisplatin) have been studied in seven patients, of whom four received the drug as a one hour infusion and three received it as a 20 h infusion. The patients receiving the drug over one hour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcc2383e33b407a03adddb7f04f116f
https://doi.org/10.1007/bf00578558

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Phase II trial of extended indications for resection in small cell carcinoma of the lung

Autor: Frederick B. Parker, Sandra J. Ginsberg, Phillip M. Ikins, Robert L. Comis, William A. Burke, Gerald A. King, John A. Meyer, Santo M. DiFino, John J. Gullo, Roger W. Tinsley

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 83:12-17

Surgical resection offers distinct theoretical advantages as the “local” modality in treatment of Stage I and II small cell carcinoma of the lung. We have treated 10 such patients by initial resection since 1975; all survivors but one received ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35680c8e5681b1951173d1f9f5888491
https://doi.org/10.1016/s0022-5223(19)37319-2

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The Prospect of Disease Control by Surgery Combined with Chemotherapy in Stage I and Stage II Small Cell Carcinoma of the Lung

Autor: Robert L. Comis, Frederick B. Parker, Sandra J. Ginsberg, William A. Burke, Phillip M. Ikins, Santo M. DiFino, John A. Meyer, John J. Gullo

Publikováno v: The Annals of Thoracic Surgery. 36:37-41

Ten patients with localized small cell carcinoma of the lung (clinical stages I and II) were treated by surgical resection more than 2 years ago; operation was followed by a course of intensive combination chemotherapy. Relapse of the disease has occ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a05e276afd280447793ba716cba5aa2
https://doi.org/10.1016/s0003-4975(10)60645-5

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Phase II studies of methyl glyoxal bis-guanylhydrazone (NSC 32946) in carcinoma of the colon and lung

Autor: John J. Gullo, Philip S. Schein, Edith P. Mitchell, Paul V. Woolley, Linda L. Willis, John Y. Killen, Frederick P. Smith, Daniel F. Hoth

Publikováno v: Cancer. 50:1258-1261

We have tested methyl glyoxal bis-guanyl hydrazone (NSC 32946) for antitumor activity in patients with colorectal carcinoma and non-small cell bronchogenic carcinoma. The drug dose was 500 mg/m2 administered by single weekly injection, and with a pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b446ea95df924701d06f15abf446456a
https://doi.org/10.1002/1097-0142(19821001)50:7<1258::aid-cncr2820500706>3.0.co

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