Two Signal Transduction Mechanisms of Substance P-induced Depolarization in Locus Coeruleus Neurons

Autor: John J. Grigg, Bratislav M. Velimirovic, Yasuko Nakajima, Shigehiro Nakajima, Konomi Koyano

Publikováno v: European Journal of Neuroscience. 5:1189-1197

Effects of substance P on cultured neurons of the locus coeruleus of the rat were studied using the whole-cell patch clamp technique. In some cells substance P produced a decrease in a K conductance which showed an inwardly rectifying property. In ot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ec4bb9ee963c8735ca2659c0d7aa4c
https://doi.org/10.1111/j.1460-9568.1993.tb00973.x

Neurotensin and substance P inhibit low- and high-voltage-activated Ca2+ channels in cultured newborn rat nucleus basalis neurons

Autor: Marta Margeta-Mitrovic, Shigehiro Nakajima, Konomi Koyano, John J. Grigg, Yasuko Nakajima

Publikováno v: Journal of neurophysiology. 78(3)

Margeta-Mitrovic, Marta, John J. Grigg, Konomi Koyano, Yasuko Nakajima, and Shigehiro Nakajima. Neurotensin and substance P inhibit low- and high-voltage-activated Ca2+channels in cultured newborn rat nucleus basalis neurons. J. Neurophysiol. 78: 134

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe466353a7a2bb56f21e9107181ca39
https://pubmed.ncbi.nlm.nih.gov/9310425

The role of arachidonic acid metabolism in somatostatin and substance P effects on inward rectifier K conductance in rat brain neurons

Autor: Shigehiro Nakajima, John J. Grigg, Bratislav M. Velimirovic, Konomi Koyano, Yasuko Nakajima

Publikováno v: Neuroscience research. 20(4)

Somatostatin enhances an inward rectifier K conductance in cultured locus coeruleus neurons, while substance P reduces an inward rectifier K conductance in cultured nucleus basalis and locus coeruleus neurons. The role of arachidonic acid metabolites

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb32393c27e3534ca24cb8d6ae5fe26f
https://pubmed.ncbi.nlm.nih.gov/7532842

Hypomyelination alters K+ channel expression in mouse mutants shiverer and Trembler

Autor: Hao Wang, Jeffrey L. Noebels, Bruce L. Tempel, Margaret L. Allen, John J. Grigg

Publikováno v: Neuron. (6):1337-1347

Voltage-gated K+ channels are localized to juxtaparanodal regions of myelinated axons. To begin to understand the role of normal compact myelin in this localization, we examined mKv1.1 and mKv1.2 expression in the dysmyelinating mouse mutants shivere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b51ef739639305bc010580986ec0f0

THE FIGHT INHERITED RETINAL BLINDNESS! PROJECT: A NEW TREATMENT OUTCOME AND NATURAL HISTORY REGISTRY FOR INHERITED RETINAL DISEASE.

Autor: Simunovic MP; Save Sight Institute, Sydney Eye Hospital Campus, 8 Macquarie St., Sydney NSW 2006, Australia.; Sydney Eye Hospital, 8 Macquarie St., Sydney NSW 2000, Australia., Moore AT; University of California at San Francisco Medical Center, 10 Koret Way, San Francisco, CA 94143, USA.; NIHR Biomedical Research Centre at Moorfields Eye Hospital, United Kingdom.; The University College London, Institute of Ophthalmology, United Kingdom., Grigg J; Save Sight Institute, Sydney Eye Hospital Campus, 8 Macquarie St., Sydney NSW 2006, Australia.; Sydney Eye Hospital, 8 Macquarie St., Sydney NSW 2000, Australia., Sergouniotis P; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, United Kingdom., Mahroo OA; NIHR Biomedical Research Centre at Moorfields Eye Hospital, United Kingdom.; The University College London, Institute of Ophthalmology, United Kingdom., Vincent A; Department of Ophthalmology, University of Auckland, Private Bag 92019, Auckland, New Zealand., Singh M; Department of Ophthalmology, University of Auckland, Private Bag 92019, Auckland, New Zealand., Fischer MD; Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21287, Maryland, USA., Edwards T; Centre for Eye Research Australia, Locked Bag 8, East Melbourne, VIC 3002, Australia., Mack H; Centre for Eye Research Australia, Locked Bag 8, East Melbourne, VIC 3002, Australia., Hogden M; Department of Ophthalmology, Princess Alexandra Hospital, 199 Ipswich Rd, Woolloongabba, Brisbane QLD 4102, Australia., Chen FK; Centre for Ophthalmology and Vision Sciences, The University of Western Australia, Perth, Western Australia, Australia., Hewitt A; Centre for Eye Research Australia, Locked Bag 8, East Melbourne, VIC 3002, Australia., Ayton L; Centre for Eye Research Australia, Locked Bag 8, East Melbourne, VIC 3002, Australia., Leroy B; Department of Ophthalmology, Ghent University Hospital, Ghent, Belgium., Jamieson R; Save Sight Institute, Sydney Eye Hospital Campus, 8 Macquarie St., Sydney NSW 2006, Australia.; Department of Clinical Genetics, Western Sydney Genetics Program, The Children's Hospital at Westmead, Sydney, NSW Australia., Gillies MC; Save Sight Institute, Sydney Eye Hospital Campus, 8 Macquarie St., Sydney NSW 2006, Australia.; Sydney Eye Hospital, 8 Macquarie St., Sydney NSW 2000, Australia., Barthelmes D; Save Sight Institute, Sydney Eye Hospital Campus, 8 Macquarie St., Sydney NSW 2006, Australia.; Department of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Publikováno v: Retina (Philadelphia, Pa.) [Retina] 2024 Oct 10. Date of Electronic Publication: 2024 Oct 10.