Zobrazeno 1 - 10
of 12
pro vyhledávání: '"John J. Gaudino"'
Autor:
Jay B, Fell, John P, Fischer, Brian R, Baer, James F, Blake, Karyn, Bouhana, David M, Briere, Karin D, Brown, Laurence E, Burgess, Aaron C, Burns, Michael R, Burkard, Harrah, Chiang, Mark J, Chicarelli, Adam W, Cook, John J, Gaudino, Jill, Hallin, Lauren, Hanson, Dylan P, Hartley, Erik J, Hicken, Gary P, Hingorani, Ronald J, Hinklin, Macedonio J, Mejia, Peter, Olson, Jennifer N, Otten, Susan P, Rhodes, Martha E, Rodriguez, Pavel, Savechenkov, Darin J, Smith, Niranjan, Sudhakar, Francis X, Sullivan, Tony P, Tang, Guy P, Vigers, Lance, Wollenberg, James G, Christensen, Matthew A, Marx
Publikováno v:
Journal of medicinal chemistry. 63(13)
Capping off an era marred by drug development failures and punctuated by waning interest and presumed intractability toward direct targeting of KRAS, new technologies and strategies are aiding in the target's resurgence. As previously reported, the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc99717000ce420f505732f20b4224e4
https://pubmed.ncbi.nlm.nih.gov/32250617
https://pubmed.ncbi.nlm.nih.gov/32250617
Autor:
Ahmed F. Abdel-Magid, Jaan A. Pesti, Rajappa Vaidyanathan, Xin Linghu, Nicholas Wong, James F. Blake, John J. Gaudino, John G. Moffat, Steven M. Mennen, John Stellwagen, Ryan D. White, David A. Thaisrivongs, William J. Morris, Jack D. Scott, Harrie J. M. Gijsen, Jinguang Lin, Yannis Houpis, Ling Tong, Joseph A. Kozlowski, Louis-Charles Campeau, Jingjun Yin, Staffan Karlsson, Daniel Pettersen, Henrik Sörensen, Darren McKerrecher, Alan Steven, Fredrik Zetterberg, Carl-Johan Aurell, James W. Leahy, Sriram Naganathan, Denise L. Andersen, Neil G. Andersen, Stephen Lau
Publikováno v:
ChemInform. 23
The data in this paper suggest that reactions of Grignard reagents with dialkylaminofuranosides derived from pentoses proceed via α-alkoxyiminium ions and that these α-alkoxyiminium ions react quite stereoselectively. The rate of this reaction is d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7db88dcc4bf5be05701da09b7646a4f2
https://doi.org/10.1002/chin.199230050
https://doi.org/10.1002/chin.199230050
Autor:
James C. Paulson, John J. Gaudino
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9e5403c0c4c242fcf6dc1d73b226044
https://doi.org/10.1002/chin.199424266
https://doi.org/10.1002/chin.199424266
Autor:
John J. Gaudino, Craig S. Wilcox
Publikováno v:
Journal of the American Chemical Society. 112:4374-4380
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c12a5d9eccad1fded35b382655e82c
https://doi.org/10.1021/ja00167a039
https://doi.org/10.1021/ja00167a039
Autor:
Shawn A. DeFrees, Federico C. A. Gaeta, Masaji Hayashi, Boliang Lou, John J. Gaudino, Lin C. Chiang, Mariann Hiroshige, Shiow Meei Chen, John Y. Ramphal
Publikováno v:
Journal of medicinal chemistry. 39(7)
Several N-acylglucosamine derivatives of sialyl Lewis X (1−3) were prepared using a combined chemical enzymatic approach and evaluated as an inhibitor of E-selectin-mediated cellular adhesion. Compounds with aromatic functionality, 1 and 2, were fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229ca61b7a0c6ef01424e8cffb707d35
https://pubmed.ncbi.nlm.nih.gov/8691465
https://pubmed.ncbi.nlm.nih.gov/8691465
Autor:
Craig S. Wilcox, John J. Gaudino
Publikováno v:
Carbohydrate research. 206(2)
The development and execution of the first examples of a new and general approach to carbocyclic analogs of carbohydrates ("pseudo-sugars") is presented. Complete experimental details for the preparation of the carbocyclic analog of beta-D-fructofura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0f5ae6564b09b96a9bd47b603c89c5
https://pubmed.ncbi.nlm.nih.gov/2073635
https://pubmed.ncbi.nlm.nih.gov/2073635
Autor:
John J. Gaudino, James C. Paulson
Publikováno v:
Journal of the American Chemical Society. 116:1149-1150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac6673999ba70e05493614037d29b49
https://doi.org/10.1021/ja00082a054
https://doi.org/10.1021/ja00082a054
Publikováno v:
Tetrahedron Letters. 29:6823-6826
In reactions with stabilized ylides, γ-lactols of ribo configuration afford 90% Z-olefins whereas γ-lactols of allo configuration afford predominantly E-olefins. Lactols of arabino configuration give intermediate results. The unusual results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a97fc30c1e20ab05f9beec385794bc
https://doi.org/10.1016/s0040-4039(00)88450-6
https://doi.org/10.1016/s0040-4039(00)88450-6
Autor:
John J. Gaudino, Craig S. Wilcox
Publikováno v:
Journal of the American Chemical Society. 108:3102-3104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d615f4f88fb775a809978bfa6603189a
https://doi.org/10.1021/ja00271a049
https://doi.org/10.1021/ja00271a049