Zobrazeno 1 - 10
of 82
pro vyhledávání: '"John J. Castellot"'
Publikováno v:
Journal of Cell Communication and Signaling. 12:217-229
Lung immaturity is the major cause of morbidity and mortality in premature infants, especially those born
Autor:
Nan Yu, Shan Gao, Zhao-Peng Deng, Min Li, Zhu-Yan Zhang, Cong Liu, Han Siying, Chang Xue, John J. Castellot
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 26, Pp 15777-15782 (2020)
ACS Omega, Vol 5, Iss 26, Pp 15777-15782 (2020)
5-Fluorouracil-nicotinamide (5-FU-NCM), a co-crystal with a 2D layer structure formed by hydrogen bonds, was synthesized by solvent evaporation and liquid phase-assisted grinding at room temperature. Compared to 5-FU alone, the results of solubility,
Autor:
Sean B. Cash, Shuchi Dhadwal, Deborah T. Kochevar, John J. Castellot, Carie Cardamone, Ellen Patterson, Deborah E. Linder
Publikováno v:
One Health
One Health, Vol 9, Iss, Pp-(2020)
One Health, Vol 9, Iss, Pp-(2020)
Today's collaborations across fields of health and wellness are insufficient to meet societies' challenges in combating disease and maintaining the ecosystem and public health. In this article, we present a One Health curriculum model designed to enc
Autor:
Min Fang, G. Gary Sahagian, Rod R. Warburton, Philip G. Haydon, Tiangmeng Chen, Ellen O. Weinberg, Heber C. Nielsen, Chang Xue, John J. Castellot, Azeem Sharda, Anne Chetty, Jinghui Dong
Publikováno v:
Journal of Asthma and Allergy
Anne Chetty,1 Azeem Sharda,1 Rod Warburton,2 Ellen O Weinberg,3 Jinghui Dong,4 Min Fang,5 G Gary Sahagian,5 Tiangmeng Chen,3 Chang Xue,3 John J Castellot,3,6 Philip G Haydon,4 Heber C Nielsen1,6 1Department of Pediatrics, Tufts Medical Center, Boston
Publikováno v:
Journal of Pharmacy and Pharmacology. 67:1585-1592
Objectives 2-Methoxyestradiol (2ME2), a metabolite of estradiol, has antitumour activity in vitro. However, potential clinical applicability has been limited by low oral bioavailability. Probenecid was evaluated in vitro as an inhibitor of 2ME2 glucu
Autor:
Alan Saghatelian, John J. Castellot, Johannes Elvin, Barbara B. Kahn, Lan Wei, Ann Hammarstedt, Claes Ohlsson, Sofia Movérare-Skrtic, Fredrik Bäckhed, Shahram Hedjazifar, Annika Nerstedt, Louise Mannerås Holm, Ismail Syed, Fatima Bosch, Jenny M. Hoffmann, John R. Grünberg, Ulf Smith, Lachmi Jenndahl
Publikováno v:
Scientific Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Grünberg, J R, Hoffmann, J M, Hedjazifar, S, Nerstedt, A, Jenndahl, L, Elvin, J, Castellot, J, Wei, L, Movérare-Skrtic, S, Ohlsson, C, Holm, L M, Bäckhed, G F, Syed, I, Bosch, F, Saghatelian, A, Kahn, B B, Hammarstedt, A & Smith, U 2017, ' Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance ', Scientific Reports, vol. 7, 43515 . https://doi.org/10.1038/srep43515
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Grünberg, J R, Hoffmann, J M, Hedjazifar, S, Nerstedt, A, Jenndahl, L, Elvin, J, Castellot, J, Wei, L, Movérare-Skrtic, S, Ohlsson, C, Holm, L M, Bäckhed, G F, Syed, I, Bosch, F, Saghatelian, A, Kahn, B B, Hammarstedt, A & Smith, U 2017, ' Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance ', Scientific Reports, vol. 7, 43515 . https://doi.org/10.1038/srep43515
WISP2 is a novel adipokine, most highly expressed in the adipose tissue and primarily in undifferentiated mesenchymal cells. As a secreted protein, it is an autocrine/paracrine activator of canonical WNT signaling and, as an intracellular protein, it
Autor:
Jonathan Z. Long, Rajesh R. Rao, Wendy Baur, Isha A. Lokurkar, Xingxing Kong, Katrin J. Svensson, Linus T.-Y. Tsai, John J. Castellot, Hyun Cheol Roh, Jesse Lou, Evan D. Rosen, Bruce M. Spiegelman, Xing Zeng
Publikováno v:
Cell Metabolism. 19:810-820
SummaryThermogenic UCP1-positive cells, which include brown and beige adipocytes, transform chemical energy into heat and increase whole-body energy expenditure. Using a ribosomal profiling approach, we present a comprehensive molecular description o
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843:797-805
Neuregulin (NRG) stimulation of ErbB4 signaling is important for type II cell surfactant synthesis. ErbB4 may mediate gene expression via a non-canonical pathway involving enzymatic cleavage releasing its intracellular domain (4ICD) for nuclear traff
Autor:
David R. Brigstock, Bernard Perbal, Lester F. Lau, Masaharu Takigawa, Philip C. Trackman, Andrew Leask, John J. Castellot
Publikováno v:
Journal of Cell Communication and Signaling. 8:71-76
In this report, chairs of the 7th International Workshop on the CCN family of Genes, review the progress made in understanding the biological functions of CCN proteins (CCN1, CCN2, CCN3, CCN4, CCN5 and CCN6) with a particular focus on their implicati
Publikováno v:
Biomolecular Concepts, Vol 4, Iss 2, Pp 173-185 (2013)
The inability of adult cells to produce well-organized, robust elastic fibers has long been a barrier to the successful engineering of certain tissues. In this review, we focus primarily on elastin with respect to tissue-engineered vascular substitut