Zobrazeno 1 - 10
of 36
pro vyhledávání: '"John J. Brewington"'
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103806- (2022)
Summary: Background: To identify host genetic variants (SNPs) associated with COVID-19 disease severity, a number of genome-wide association studies (GWAS) have been conducted. Since most of the identified variants are located at non-coding regions,
Externí odkaz:
https://doaj.org/article/6799e39562c846f7ad4595873c0cd4a3
Autor:
Galit Livnat, Jessica D. Meeker, Alicia J. Ostmann, Lauren M. Strecker, John P. Clancy, John J. Brewington
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1246 (2023)
Cystic Fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR), a chloride/bicarbonate channel. Many studies utilize human airway cell models (cell lines and primary cells) to study different aspects of CFTR biology.
Externí odkaz:
https://doaj.org/article/347effde1cc14b6f8b399e748056b318
Autor:
Duncan E. Keegan, John J. Brewington
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4448 (2021)
The emergence of highly effective CFTR modulator therapy has led to significant improvements in health care for most patients with cystic fibrosis (CF). For some, however, these therapies remain inaccessible due to the rarity of their individual CFTR
Externí odkaz:
https://doaj.org/article/5046e523c2ed48e58b76584d92d3bf10
Autor:
Danieli B. Salinas, Daniella K. Ginsburg, Choo Phei Wee, Muhammed M. Saeed, John J. Brewington
Publikováno v:
Pediatric pulmonology.
Universal implementation of cystic fibrosis (CF) newborn screening (NBS) has led to the diagnostic dilemma of infants with CF screen positive, inconclusive diagnosis (CFSPID), with limited guidance regarding prognosis and standardized care. Rates of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12259a799be838d4fd29f83e2db5fc05
https://pubmed.ncbi.nlm.nih.gov/36582049
https://pubmed.ncbi.nlm.nih.gov/36582049
Publikováno v:
Clinics in chest medicine. 43(4)
As routine care in cystic fibrosis (CF) becomes increasingly personalized, new opportunities to further focus care on the individual have emerged. These opportunities are increasingly filled through research in tools aiding drug selection, drug monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f4071d82e8dcced33412d1e75b94d4
https://pubmed.ncbi.nlm.nih.gov/36344070
https://pubmed.ncbi.nlm.nih.gov/36344070
Autor:
Anjaparavanda P. Naren, Alexander R. Cortez, Herbert Luke Ogden, Kavisha Arora, John J. Brewington, Fanmuyi Yang, John P. Clancy, Nambirajan Sundaram, Michael A. Helmrath, Yashaswini Ramananda, Gary L. McPhail
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Cystic fibrosis is a deadly multiorgan disorder caused by loss of function mutations in the gene that encodes for the cystic fibrosis transmembrane conductance regulator (CFTR) chloride/bicarbonate ion channel. More than 1,700 CFTR genetic variants e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8db53beb5386cb91d568dcc3e6030a
https://doi.org/10.1152/ajpgi.00095.2021
https://doi.org/10.1152/ajpgi.00095.2021
Publikováno v:
Pediatric Pulmonology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dfa3f80c216fadb675c9c48e593635
https://pubmed.ncbi.nlm.nih.gov/33559942
https://pubmed.ncbi.nlm.nih.gov/33559942
Autor:
Teresa Pestian, Cole Brokamp, Eleni-Rosalina Andrinopoulou, Rhonda D. Szczesniak, Weiji Su, Francis J. LaRosa, George M. Solomon, Emrah Gecili, John P. Clancy, John J. Brewington
Publikováno v:
J Cyst Fibros
Journal of Cystic Fibrosis, 20(5), e69-e71. Elsevier
Journal of Cystic Fibrosis, 20(5), e69-e71. Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81044315a00d4ca9aafb87cbf31394d
https://pubmed.ncbi.nlm.nih.gov/33958278
https://pubmed.ncbi.nlm.nih.gov/33958278
The pandemic has had a dramatic and negative impact on opportunities for training in pediatric airway endoscopy. This commentary discusses ways in which training programs can address this issue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f373b7689399aa20479fd838295a21
https://doi.org/10.22541/au.160927201.11232617/v1
https://doi.org/10.22541/au.160927201.11232617/v1
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 21(1)
There has been a growing number of infants identified as CRMS/CFSPID in countries applying genetic testing as part of cystic fibrosis (CF) newborn screening. Currently there are neither standardized protocols for follow up beyond infancy, nor establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850d9c17543b68f063b8caa15f327a95
https://pubmed.ncbi.nlm.nih.gov/34756682
https://pubmed.ncbi.nlm.nih.gov/34756682