Zobrazeno 1 - 10
of 28
pro vyhledávání: '"John J. Ambre"'
Publikováno v:
Journal of Analytical Toxicology. 15:17-20
Cocaine (C) and benzoylecgonine (BZ) plasma levels and urinary excretion rate data from a series of intravenous cocaine studies were used to develop a kinetic model for C and BZ, with the main objective of characterizing BZ disposition. Kinetic analy
Autor:
John J. Ambre
Publikováno v:
JAMA: The Journal of the American Medical Association. 266:1513
In Reply. —The well-known and widely available publication of the American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition 1 provides guidelines in terms of diagnostic criteria for distinguishin
Autor:
John J. Ambre
Publikováno v:
JAMA: The Journal of the American Medical Association. 265:1529
In Reply. — As pointed out by Drs Amelar and Dubin, chorionic gonadotropin is a glycoprotein, not a steroid. It is similar in structure to the other glycoprotein gonadotropins, luteinizing hormone and follicle-stimulating hormone, and also resemble
Publikováno v:
Toxicology and Applied Pharmacology. 36:595-601
The effect of methanol and other alcohols, sodium formate, and known vasoactive agents on isolated canine basilar artery was examined. Clinical concentrations of either methanol or sodium formate (approx 200 and 60 mg/100 ml, respectively) produced s
Autor:
Arthur J. Atkinson, John J. Ambre, Marian W Fischman, May J. Chow, Tsuen Ih Ruo, Dennis J. Bowsher
Publikováno v:
Clinical Pharmacology and Therapeutics. 38:318-324
The pharmacokinetics of cocaine were studied in five subjects with histories of drug abuse who were otherwise healthy. A two-compartment system was used to model the distribution kinetics of the drug. The steady-state volume of distribution averaged
Publikováno v:
Anesthesiology. 49:274-277
Etomidate sulfate, 0.3 mg/kg, was administered intravenously to eight patients and venous blood samples were drawn at intervals for the subsequent 10 hours. Plasma etomidate was determined by mass fragmentography. Plasma concentrations were fitted to
Publikováno v:
Clinical Pharmacology and Therapeutics. 39:163-168
Prednisolone pharmacokinetics were compared in seven patients with asthma managed by alternate-day prednisone therapy and in seven patients with asthma requiring daily doses of prednisone. Steroid requirements of these patients were carefully charact
Publikováno v:
The American Journal of Medicine. 68:414-418
Whereas a great deal of information is available on the etiology of methanol poisoning in the monkey, very little study has been made in human subjects. The role of formic acid in methanol toxicity in human subjects has not been established. Two pati
Publikováno v:
Journal of Pharmaceutical Sciences. 66:1344-1346
The intravenous anesthetic etomidate was measured in human plasma by mass fragmentography. The method is accurate, sensitive, and specific. Results of the analyses indicate that after a single 0.3-mg/kg iv dose of etomidate, there are at least three
Publikováno v:
Annals of Emergency Medicine. 15:724-726
We describe three analytical procedures that can be used to distinguish naphthalene from the less toxic mothball component paradichlorobenzene. An initial presumptive identification can be made by noting the characteristic aroma of the two substances