Zobrazeno 1 - 10
of 199
pro vyhledávání: '"John J Woodward"'
Autor:
Sudarat Nimitvilai, Chang You, Devinder Singh Arora, Maureen A. McElvain, Bertha J. Vandegrift, Mark S. Brodie, John J Woodward
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Drugs of abuse increase the activity of dopaminergic neurons of the ventral tegmental area (VTA), and output from the VTA is critical for both natural and drug-induced reward and reinforcement. Ethanol and the abused inhalant toluene both enhance VTA
Externí odkaz:
https://doaj.org/article/df8dd49a94c34b9cac1429a2af1b0b01
Autor:
Matthew J Pava, Carolina R den Hartog, Carlos Blanco-Centurion, Priyattam J Shiromani, John J Woodward
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88672 (2014)
Up-/down-state transitions are a form of network activity observed when sensory input into the cortex is diminished such as during non-REM sleep. Up-states emerge from coordinated signaling between glutamatergic and GABAergic synapses and are modulat
Externí odkaz:
https://doaj.org/article/e5ff91085e8844f7aff44b028dfe4df5
Autor:
Carolina R den Hartog, Jacob T Beckley, Thetford C Smothers, Daniel H Lench, Zack L Holseberg, Hleb Fedarovich, Meghin J Gilstrap, Gregg E Homanics, John J Woodward
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80541 (2013)
Ethanol's action on the brain likely reflects altered function of key ion channels such as glutamatergic N-methyl-D-aspartate receptors (NMDARs). In this study, we determined how expression of a mutant GluN1 subunit (F639A) that reduces ethanol inhib
Externí odkaz:
https://doaj.org/article/06d7daba69424c37973b5e3a96f4f721
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2012)
The granule cell layer of the cerebellum functions in spatio-temporal encoding of information. Granule cells are tonically inhibited by spillover of GABA released from Golgi cells and this tonic inhibition is facilitated by acute ethanol. Recently it
Externí odkaz:
https://doaj.org/article/bd95dbf334a44b2182b29c9d59e4aea4
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionInhalant abuse is an important health issue especially among children and adolescents who often encounter these agents in the home. Research into the neurobiological targets of inhalants has lagged behind that of other drugs such as alcoh
Externí odkaz:
https://doaj.org/article/d8c87632647f42a1925596da721dc3e8
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Although volatile organic solvents such as toluene are used for commercial and industrial uses, they are often voluntarily inhaled for their intoxicating and euphoric effects. Research into the effects of inhalants such as toluene on brain function h
Externí odkaz:
https://doaj.org/article/4542b80e38514299938c9019b7b8386c
Publikováno v:
Alcohol. 106:44-54
Examining neural circuits underlying persistent, heavy drinking provides insight into the neurobiological mechanisms driving alcohol use disorder. Facilitated by its connectivity with other parts of the brain such as the nucleus accumbens (NAc), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6743f2a973bbfc057423481eb60a7a
https://doi.org/10.1016/j.alcohol.2022.10.004
https://doi.org/10.1016/j.alcohol.2022.10.004
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Inhalants, including volatile organic solvents such as toluene, continue to be one of the most prevalent, and often first substances abused by adolescents. Like other drugs of abuse, toluene affects the function of neurons within key brain reward cir
Externí odkaz:
https://doaj.org/article/fae28a4a9d5c43269df833977b407f66
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:1665-1676
The basolateral nucleus of the amygdala (BLA) plays an important role in the development of fear and anxiety-related behaviors. The BLA receives inputs from all sensory stimuli. After processing those stimuli, BLA neurons signal neurons within the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1c2417e3622d47031dfd083d2ee68c
https://doi.org/10.1111/acer.14918
https://doi.org/10.1111/acer.14918
Autor:
Todd B. Nentwig, Dylan T. Vaughan, Kevin M. Braunscheidel, Brittney D. Browning, John J. Woodward, L. Judson Chandler
Publikováno v:
Neuropsychopharmacology. 47:2123-2131
The lateral habenula (LHb) is an epithalamic nuclei that has been shown to signal the aversive properties of ethanol. The present study tested the hypothesis that activity of the LHb is required for the acquisition and/or expression of dependence-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efb2363f1e5c7a7f56b189fe459205f
https://doi.org/10.1038/s41386-022-01357-7
https://doi.org/10.1038/s41386-022-01357-7