Zobrazeno 1 - 10
of 178
pro vyhledávání: '"John J Welch"'
Autor:
Benjamin G Butt, Danielle J Owen, Cy M Jeffries, Lyudmila Ivanova, Chris H Hill, Jack W Houghton, Md Firoz Ahmed, Robin Antrobus, Dmitri I Svergun, John J Welch, Colin M Crump, Stephen C Graham
Publikováno v:
eLife, Vol 9 (2020)
Herpesviruses acquire their membrane envelopes in the cytoplasm of infected cells via a molecular mechanism that remains unclear. Herpes simplex virus (HSV)−1 proteins pUL7 and pUL51 form a complex required for efficient virus envelopment. We show
Externí odkaz:
https://doaj.org/article/cfd82648c6a14487a1d5e6ed851657bb
Publikováno v:
PLoS Pathogens, Vol 10, Iss 11, p e1004395 (2014)
Emerging viral diseases are often the product of a host shift, where a pathogen jumps from its original host into a novel species. Phylogenetic studies show that host shifts are a frequent event in the evolution of most pathogens, but why pathogens s
Externí odkaz:
https://doaj.org/article/f5f2e9cff3ac46748f6ed1c8d9ee680b
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48382 (2012)
Deleterious mutations can have a strong influence on the outcome of evolution. The nature of this influence depends on how mutations combine together to affect fitness. "Negative epistasis" occurs when a new deleterious mutation causes the greatest l
Externí odkaz:
https://doaj.org/article/8fecd3e625ec4acb9a2ded70b1ed4ca9
Autor:
Andrew E Armitage, Koen Deforche, Chih-Hao Chang, Edmund Wee, Beatrice Kramer, John J Welch, Jan Gerstoft, Lars Fugger, Andrew McMichael, Andrew Rambaut, Astrid K N Iversen
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002550 (2012)
The rapid evolution of Human Immunodeficiency Virus (HIV-1) allows studies of ongoing host-pathogen interactions. One key selective host factor is APOBEC3G (hA3G) that can cause extensive and inactivating Guanosine-to-Adenosine (G-to-A) mutation on H
Externí odkaz:
https://doaj.org/article/6f45eb3791ca4b24bad496dec70d31c2
Autor:
Mark F Richardson, Lucy A Weinert, John J Welch, Raquel S Linheiro, Michael M Magwire, Francis M Jiggins, Casey M Bergman
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003129 (2012)
Wolbachia are maternally inherited symbiotic bacteria, commonly found in arthropods, which are able to manipulate the reproduction of their host in order to maximise their transmission. The evolutionary history of endosymbionts like Wolbachia can be
Externí odkaz:
https://doaj.org/article/bd8fdebdf71744f9913c9fb7442289d3
Autor:
John J Welch
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8776 (2010)
One of the most intriguing patterns in mammalian biogeography is the "island rule", which states that colonising species have a tendency to converge in body size, with larger species evolving decreased sizes and smaller species increased sizes. It ha
Externí odkaz:
https://doaj.org/article/25e6c628208b4dbe80dcced5b20f1e0c
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000698 (2009)
It is estimated that a large proportion of amino acid substitutions in Drosophila have been fixed by natural selection, and as organisms are faced with an ever-changing array of pathogens and parasites to which they must adapt, we have investigated t
Externí odkaz:
https://doaj.org/article/05ef1dd6685c4330abf660be93f49e72
Autor:
Marta Matuszewska, Alicja Dabrowska, Gemma G. R. Murray, Steve M. Kett, Andy J. A. Vick, Sofie C. Banister, Leonardo Pantoja Munoz, Peter Cunningham, John J. Welch, Mark A. Holmes, Lucy A. Weinert
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Staphylococcus aureus is a human commensal and opportunistic pathogen that also infects other animals. In humans and livestock, where S. aureus is most studied, strains are specialized for different host species. Recent studies have also fou
Externí odkaz:
https://doaj.org/article/cb121dfb685040b9bc8e47b0e7df6d6f
Publikováno v:
Peer Community Journal. 3
When divergent populations interbreed, the outcome will be affected by the genomic and phenotypic differences that they have accumulated. In this way, the mode of evolutionary divergence between populations may have predictable consequences for the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b78f83569215e27018c8cd2aed27768
https://doi.org/10.24072/pcjournal.226
https://doi.org/10.24072/pcjournal.226
Autor:
John J. Welch
Publikováno v:
Evolutionary Biology: Contemporary and Historical Reflections Upon Core Theory ISBN: 9783031220272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db3616168274b6c561c102d2c5d0bc9
https://doi.org/10.1007/978-3-031-22028-9_5
https://doi.org/10.1007/978-3-031-22028-9_5
