Zobrazeno 1 - 10
of 350
pro vyhledávání: '"John J Stegeman"'
Autor:
Djamal Brahim Belhaouari, Gabriel Augusto Pires De Souza, David C Lamb, Steven L Kelly, Jared V Goldstone, John J Stegeman, Philippe Colson, Bernard La Scola, Sarah Aherfi
Publikováno v:
eLife, Vol 11 (2022)
Viruses generally are defined as lacking the fundamental properties of living organisms in that they do not harbor an energy metabolism system or protein synthesis machinery. However, the discovery of giant viruses of amoeba has fundamentally challen
Externí odkaz:
https://doaj.org/article/b09784e9d64b4b65bdc673a3866ba9c5
Autor:
Mark E Hahn, Andrew G McArthur, Sibel I Karchner, Diana G Franks, Matthew J Jenny, Alicia R Timme-Laragy, John J Stegeman, Bruce R Woodin, Michael J Cipriano, Elwood Linney
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113158 (2014)
Oxidative stress is an important mechanism of chemical toxicity, contributing to teratogenesis and to cardiovascular and neurodegenerative diseases. Developing animals may be especially sensitive to chemicals causing oxidative stress. The development
Externí odkaz:
https://doaj.org/article/9f04281701d54484a502ec62aef1c01a
Autor:
Larissa M Williams, Alicia R Timme-Laragy, Jared V Goldstone, Andrew G McArthur, John J Stegeman, Roxanna M Smolowitz, Mark E Hahn
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e79574 (2013)
Transcription factors in the CNC-bZIP family (NFE2, NRF1, NRF2 and NRF3) regulate genes with a wide range of functions in response to both physiological and exogenous signals, including those indicating changes in cellular redox status. Given their r
Externí odkaz:
https://doaj.org/article/b5fbe07a77e846d2b1fd012c2de153f7
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28257 (2011)
Cytochrome P450 1 (CYP1) genes are biomarkers for aryl hydrocarbon receptor (AHR) agonists and may be involved in some of their toxic effects. CYP1s other than the CYP1As are poorly studied in birds. Here we characterize avian CYP1B and CYP1C genes a
Externí odkaz:
https://doaj.org/article/a856c42f52be49c78302d703870a9a2d
Autor:
Philip J. Landrigan, Hervé Raps, Maureen Cropper, Caroline Bald, Manuel Brunner, Elvia Maya Canonizado, Dominic Charles, Thomas C. Chiles, Mary J. Donohue, Judith Enck, Patrick Fenichel, Lora E. Fleming, Christine Ferrier-Pages, Richard Fordham, Aleksandra Gozt, Carly Griffin, Mark E. Hahn, Budi Haryanto, Richard Hixson, Hannah Ianelli, Bryan D. James, Pushpam Kumar, Amalia Laborde, Kara Lavender Law, Keith Martin, Jenna Mu, Yannick Mulders, Adetoun Mustapha, Jia Niu, Sabine Pahl, Yongjoon Park, Maria-Luiza Pedrotti, Jordan Avery Pitt, Mathuros Ruchirawat, Bhedita Jaya Seewoo, Margaret Spring, John J. Stegeman, William Suk, Christos Symeonides, Hideshige Takada, Richard C. Thompson, Andrea Vicini, Zhanyun Wang, Ella Whitman, David Wirth, Megan Wolff, Aroub K. Yousuf, Sarah Dunlop
Publikováno v:
Annals of Global Health, Vol 89, Iss 1 (2023)
Background: Plastics have conveyed great benefits to humanity and made possible some of the most significant advances of modern civilization in fields as diverse as medicine, electronics, aerospace, construction, food packaging, and sports. It is now
Externí odkaz:
https://doaj.org/article/a834c3854b20442aa2800c81e5151a61
Autor:
Philip J. Landrigan, Hervé Raps, Maureen Cropper, Caroline Bald, Manuel Brunner, Elvia Maya Canonizado, Dominic Charles, Thomas C. Chiles, Mary J. Donohue, Judith Enck, Patrick Fenichel, Lora E. Fleming, Christine Ferrier-Pages, Richard Fordham, Aleksandra Gozt, Carly Griffin, Mark E. Hahn, Budi Haryanto, Richard Hixson, Hannah Ianelli, Bryan D. James, Pushpam Kumar, Amalia Laborde, Kara Lavender Law, Keith Martin, Jenna Mu, Yannick Mulders, Adetoun Mustapha, Jia Niu, Sabine Pahl, Yongjoon Park, Maria-Luiza Pedrotti, Jordan Avery Pitt, Mathuros Ruchirawat, Bhedita Jaya Seewoo, Margaret Spring, John J. Stegeman, William Suk, Christos Symeonides, Hideshige Takada, Richard C. Thompson, Andrea Vicini, Zhanyun Wang, Ella Whitman, David Wirth, Megan Wolff, Aroub K. Yousuf, Sarah Dunlop
Publikováno v:
Annals of Global Health, Vol 89, Iss 1, Pp 71-71 (2023)
This article details a correction to: Landrigan PJ, Raps H, Cropper M, et al. The Minderoo-Monaco Commission on Plastics and Human Health. Annals of Global Health. 2023; 89(1): 23. DOI: https://doi.org/10.5334/aogh.4056.
Externí odkaz:
https://doaj.org/article/6e03b4f3d2604762bba108466b0e742a
Autor:
David C. Lamb, Jared V. Goldstone, Bin Zhao, Li Lei, Jonathan G. L. Mullins, Michael J. Allen, Steven L. Kelly, John J. Stegeman
Publikováno v:
Biomolecules; Volume 12; Issue 8; Pages: 1107
Flavodoxins are small electron transport proteins that are involved in a myriad of photosynthetic and non-photosynthetic metabolic pathways in Bacteria (including cyanobacteria), Archaea and some algae. The sequenced genome of 0305φ8-36, a large bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc9073629a16d32d66d2d954e139f1b
https://cronfa.swan.ac.uk/Record/cronfa62081/Download/62081__26030__f79a912a039444e69fbdc923d91af87f.pdf
https://cronfa.swan.ac.uk/Record/cronfa62081/Download/62081__26030__f79a912a039444e69fbdc923d91af87f.pdf
Publikováno v:
Toxicol Sci
Pregnane X receptor (PXR; NR1I2) is a nuclear receptor that regulates transcriptional responses to drug or xenobiotic exposure, including induction of CYP3A transcription, in many vertebrate species. PXR is activated by a wide range of ligands that d
Autor:
Nadja R. Brun, Matthew C. Salanga, Francisco X. Mora-Zamorano, David C. Lamb, Jared V. Goldstone, John J. Stegeman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Orphan cytochrome P450 (CYP) enzymes are those for which biological substrates and function(s) are unknown. Cytochrome P450 20A1 (CYP20A1) is the last human orphan P450 enzyme, and orthologs occur as single genes in every vertebrate genome sequenced
Autor:
Francisco X. Mora-Zamorano, John J. Stegeman, Jared V. Goldstone, Matthew C. Salanga, David C. Lamb, Nadja R. Brun
Orphan cytochrome P450 (CYP) enzymes are those for which biological substrates and function(s) are unknown. Cytochrome P450 20A1 (CYP20A1) is the last human orphan P450 enzyme, and orthologs occur as single genes in every vertebrate genome sequenced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0ffeee36f0f7aeb0504a1256a04dc5
https://doi.org/10.1101/2021.07.23.453406
https://doi.org/10.1101/2021.07.23.453406