Zobrazeno 1 - 10
of 652
pro vyhledávání: '"John J Ryan"'
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60640 (2013)
The generation of antigen-specific antibodies and the development of immunological memory require collaboration between B and T cells. T cell-secreted IL-4 is important for B cell survival, isotype switch to IgG1 and IgE, affinity maturation, and the
Externí odkaz:
https://doaj.org/article/6fb5af0431574801abf5aa50479bdc8b
Autor:
Megan Mayer, David B. Badesch, Kelly H. Nielsen, Steven Kawut, Todd Bull, John J. Ryan, Jeffrey Sager, Sula Mazimba, Anna Hemnes, James Klinger, James Runo, John W. McConnell, Teresa De Marco, Murali M. Chakinala, Delphine Yung, Jean Elwing, Adolfo Kaplan, Rahul Argula, Raymond Pomponio, Ryan Peterson, Peter Hountras
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract To better understand the impact of the COVID‐19 pandemic on the care of patients with pulmonary hypertension, we conducted a retrospective cohort study evaluating health insurance status, healthcare access, disease severity, and patient re
Externí odkaz:
https://doaj.org/article/2e5ecf9698454f89883f1139645ab4b7
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-6 (2022)
Abstract Background This case report demonstrates acute myeloid leukemia causing acute thrombosis of coronary arteries with anterolateral ST elevation myocardial infarction and ventricular tachycardia in an otherwise healthy woman. Few case reports h
Externí odkaz:
https://doaj.org/article/467db82fef9644c184435e8ed467b62f
Autor:
Aneel R. Bhagwani, Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil Kelly, Srimathi Bogamuwa, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan, A.A. Roger Thompson, Stephen Y. Chan, Delphine Gomez, Elena A. Goncharova, Laszlo Farkas
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105935- (2023)
Summary: Pulmonary arterial hypertension (PAH) features pathogenic and abnormal endothelial cells (ECs), and one potential origin is clonal selection. We studied the role of p53 and toll-like receptor 3 (TLR3) in clonal expansion and pulmonary hypert
Externí odkaz:
https://doaj.org/article/8a31db23f5614a919e0d4eb917f3b10d
Autor:
Meganne N. Ferrel, Sentia Iriana, I. Raymond Thomason, Christy L. Ma, Katsiaryna Tsarova, Brent D. Wilson, Stephen H. McKellar, John J. Ryan
Publikováno v:
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Constrictive pericarditis (CP) is characterized by scarring and loss of elasticity of the pericardium. This case demonstrates that mixed martial arts (MMA) is a previously unrecognized risk factor for CP, diagnosis of which is sup
Externí odkaz:
https://doaj.org/article/4613c91f452c4a17893aaf069e7ec6df
Autor:
Jasleen Minhas, Sai Prasanna Narasimmal, Todd M. Bull, Teresa De Marco, John Wesley McConnell, Matthew R. Lammi, Thenappan Thenappan, Jeremy P. Feldman, Jeffrey S. Sager, David B. Badesch, John J. Ryan, Daniel C. Grinnan, Dianne Zwicke, Evelyn M. Horn, Jean M. Elwing, John E. Moss, Michael Eggert, Oksana A. Shlobin, Robert P. Frantz, Sonja D. Bartolome, Stephen C. Mathai, Sula Mazimba, Steven C. Pugliese, Nadine Al‐Naamani, PHAR investigators
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-11 (2021)
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, morbid, potentially curable subtype of pulmonary hypertension that negatively impacts health‐related quality of life (HRQoL). Little is known about differences in HRQoL and hospitaliz
Externí odkaz:
https://doaj.org/article/7630fe6521244aa0b6585bc803767e68
Autor:
Hilary M. DuBrock, Charles D. Burger, Sonja D. Bartolome, Jeremy P. Feldman, David D. Ivy, Erika B. Rosenzweig, Jeffrey S. Sager, Kenneth W. Presberg, Stephen C. Mathai, Matthew R. Lammi, James R. Klinger, Michael Eggert, Teresa De Marco, Jean M. Elwing, David Badesch, Todd M. Bull, Linda M. Cadaret, Gautam Ramani, Thenappan Thenappan, H. James Ford, Nadine Al‐Naamani, Marc A. Simon, Sula Mazimba, James R. Runo, Murali Chakinala, Evelyn M. Horn, John J. Ryan, Robert P. Frantz, Michael J. Krowka, PHAR Investigators
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 4, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/ff7d574098134b25b2891ef16f2df205
Autor:
John J. Ryan, Mardi Gomberg‐Maitland
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Externí odkaz:
https://doaj.org/article/47d6e240a93c40dcb3bf3ff35013c5d3
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 2, Pp n/a-n/a (2022)
Abstract Protein kinase inhibitors (PKIs) have been implicated in pulmonary vascular toxicities including risk factors for at least three of the five World Health Organization groups of pulmonary hypertension (PH). These toxicities include direct dru
Externí odkaz:
https://doaj.org/article/fb5a4396e4dc42f5bb67ee5bf98f334d
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Lactate and the associated H+ ions are still introduced in many biochemistry and general biology textbooks and courses as a metabolic by-product within fast or oxygen-independent glycolysis. However, the role of lactate as a fuel source has been well
Externí odkaz:
https://doaj.org/article/61b4284732ce438dbcf824c344cf0648