Zobrazeno 1 - 10
of 86
pro vyhledávání: '"John J Pink"'
Autor:
Jing Jie Yu, Pingfu Fu, John J Pink, Dawn Dawson, Jay Wasman, Jackson Orem, Walter O Mwanda, Honglan Zhu, Xiaobing Liang, Yi Guo, William P Petros, Ronald T Mitsuyasu, Henry Wabinga, Scot C Remick
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10477 (2010)
There has been substantial growth in the numbers of patients with conjunctival squamous cell carcinoma infected with HIV in East Africa. The natural history of the conjunctival squamous cell carcinoma appears to be unique in this region of the world,
Externí odkaz:
https://doaj.org/article/6a79650671f44803bdd2925eec6493ee
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8318bc1fc1685fb9a480cc9c002a5fa7
https://doi.org/10.1158/1541-7786.22515339
https://doi.org/10.1158/1541-7786.22515339
Thymidylate synthase (TS) inhibitors including fluoropyrimidines [e.g., 5-Fluorouracil (5-FU) and 5-Fluorodeoxyuridine (5-FdU, floxuridine)] and antifolates (e.g., pemetrexed) are widely used against solid tumors. Previously, we reported that shRNA-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33dbe38b0ac83f47b607b70fb7653392
https://doi.org/10.1158/1541-7786.c.6541047.v1
https://doi.org/10.1158/1541-7786.c.6541047.v1
Autor:
David A. Boothman, Jinming Gao, Douglas R. Spitz, Donald J. Buchsbaum, William G. Bornmann, David M. Euhus, Cheryl Lewis, Michael Boatman, Amy Rommel, Zachary Moore, Lifen Cao, Malina Patel, Long Shan Li, John J. Pink, Vernon E. Anderson, Marie Varnes, Melissa C. Srougi, Kathryn E. Reinicke, Erik A. Bey
PDF file, 1661K, Supplemental Figure S1- Chemical Structures. Supplemental Figure S2-Oxygen Consumption in MCF-7 Cells treated with or without betalapchone and dicoumarol. Supplemental Figure S2 legend. Supplemental Figure S3-Survival assay for norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0292db08a0f90fe3921f701ed3216c
https://doi.org/10.1158/1535-7163.22498413.v1
https://doi.org/10.1158/1535-7163.22498413.v1
Figure S1 shows the effect of irradiation on p21 induction in various cancer cells with different p53 status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b7356459863360803135991fd0c852
https://doi.org/10.1158/1541-7786.22515336
https://doi.org/10.1158/1541-7786.22515336
Autor:
Mitchell Machtay, Stanton L. Gerson, Monaliben Patel, David L. Bajor, Debora S. Bruno, Shufen Cao, Pingfu Fu, Shakun Malik, Nancy L. Oleinick, John J. Pink, Charles A. Kunos, Afshin Dowlati, Tithi Biswas
Purpose:TRC102, a small-molecule base-excision repair inhibitor, potentiates the cytotoxicity of pemetrexed and reverses resistance by binding to chemotherapy-induced abasic sites in DNA. We conducted a phase I clinical trial combining pemetrexed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ee52ebdeb49d0abe7e18d85aaed4c0
https://doi.org/10.1158/1078-0432.c.6531291.v1
https://doi.org/10.1158/1078-0432.c.6531291.v1
Autor:
Mitchell Machtay, Stanton L. Gerson, Monaliben Patel, David L. Bajor, Debora S. Bruno, Shufen Cao, Pingfu Fu, Shakun Malik, Nancy L. Oleinick, John J. Pink, Charles A. Kunos, Afshin Dowlati, Tithi Biswas
Supplementary Data from Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed–Platinum–Radiation in Patients with Advanced Nonsquamous Non–Small Cell Lung Cancer: Results of a Phase I Trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4154f925bb072fc0960c03a8ac23962e
https://doi.org/10.1158/1078-0432.22483995
https://doi.org/10.1158/1078-0432.22483995
Autor:
Pingfu Fu, Monaliben Patel, John J. Pink, Tithi Biswas, Mitchell Machtay, Shufen Cao, Charles A Kunos, Debora S. Bruno, Stanton L. Gerson, David L. Bajor, Nancy L. Oleinick, Shakun Malik, Afshin Dowlati
Publikováno v:
Clin Cancer Res
Purpose: TRC102, a small-molecule base-excision repair inhibitor, potentiates the cytotoxicity of pemetrexed and reverses resistance by binding to chemotherapy-induced abasic sites in DNA. We conducted a phase I clinical trial combining pemetrexed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad685249764bb7df5be0c6d6832b2e0
https://doi.org/10.1158/1078-0432.ccr-21-2025
https://doi.org/10.1158/1078-0432.ccr-21-2025
Autor:
John A. Tainer, Darin E. Jones, Yan Yan, Davide Moiani, John J. Pink, Stanton L. Gerson, Daniel J. Laverty, Sarita Namjoshi, Dave S. Shin, Yuriy Fedorov, Zamal Ahmed, My T. Nguyen, Andrew S. Arvai, Zachary D. Nagel, Edward J. Selvik
Publikováno v:
Progress in biophysics and molecular biology
Human uracil DNA-glycosylase (UDG) is the prototypic and first identified DNA glycosylase with a vital role in removing deaminated cytosine and incorporated uracil and 5-fluorouracil (5-FU) from DNA. UDG depletion sensitizes cells to high APOBEC3B de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b56ffc793d58107fe40a464f176770b
https://doi.org/10.1016/j.pbiomolbio.2021.02.004
https://doi.org/10.1016/j.pbiomolbio.2021.02.004
Autor:
Sheena T. Hill, Jeremy S. Bordeaux, Kevin D. Cooper, Amanda W. Lund, Sancy A. Leachman, Rajan P. Kulkarni, Wesley Y. Yu, John J. Pink, E. Ricky Chan
Publikováno v:
J Invest Dermatol
Despite advances in melanoma treatment, more than 70% of patients with distant metastasis die within 5 years. Proactive treatment of early melanoma to prevent metastasis could save lives and reduce overall healthcare costs. Currently, there are no tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f631cd309c4d1c556b814a476b7d40c6
https://doi.org/10.1016/j.jid.2020.12.015
https://doi.org/10.1016/j.jid.2020.12.015