Zobrazeno 1 - 10
of 51
pro vyhledávání: '"John J P Brevé"'
Autor:
Navina L Chrobok, John G J M Bol, Cornelis A Jongenelen, John J P Brevé, Said El Alaoui, Javier Fidalgo-Lopez, Guy Fournet, Benoît Joseph, Micha M M Wilhelmus, Benjamin Drukarch, Anne-Marie van Dam
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209522 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0196433.].
Externí odkaz:
https://doaj.org/article/44f960c300d941f48c350c8bb4c22aa2
Autor:
Navina L Chrobok, John G J M Bol, Cornelis A Jongenelen, John J P Brevé, Said El Alaoui, Micha M M Wilhelmus, Benjamin Drukarch, Anne-Marie van Dam
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196433 (2018)
The neurodegenerative disease multiple sclerosis (MS) is pathologically characterized by the massive influx of immune cells into the central nervous system. This contributes to demyelination and axonal damage which causes symptoms such as motor and c
Externí odkaz:
https://doaj.org/article/291e2b1b073541f8804ee43b73360e0d
Autor:
Miriam E van Strien, John J P Brevé, Silvina Fratantoni, Marco W J Schreurs, John G J M Bol, Cornelis A M Jongenelen, Benjamin Drukarch, Anne-Marie van Dam
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25037 (2011)
An important neuropathological feature of neuroinflammatory processes that occur during e.g. Multiple Sclerosis (MS) is the formation of an astroglial scar. Astroglial scar formation is facilitated by the interaction between astrocytes and extracellu
Externí odkaz:
https://doaj.org/article/67c9686983904bc3a3b0f15fff4bd5cf
Autor:
Davide Iannuzzi, John J. P. Brevé, Anne Marie van Dam, Erik Paardekam, Thecla A. van Wageningen, Nelda Antonovaite
Publikováno v:
van Wageningen, T A, Antonovaite, N, Paardekam, E, Brevé, J J P, Iannuzzi, D & van Dam, A-M 2021, ' Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin ', Journal of Neuroinflammation, vol. 18, no. 1, 83 . https://doi.org/10.1186/s12974-021-02134-x
van Wageningen, T A, Antonovaite, N, Paardekam, E, Brevé, J J P, Iannuzzi, D & van Dam, A M 2021, ' Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin ', Journal of Neuroinflammation, vol. 18, 83, pp. 1-15 . https://doi.org/10.1186/s12974-021-02134-x
Journal of Neuroinflammation, 18:83, 1-15. BioMed Central
Journal of Neuroinflammation, 18(1):83. BioMed Central
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Journal of Neuroinflammation
van Wageningen, T A, Antonovaite, N, Paardekam, E, Brevé, J J P, Iannuzzi, D & van Dam, A M 2021, ' Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin ', Journal of Neuroinflammation, vol. 18, 83, pp. 1-15 . https://doi.org/10.1186/s12974-021-02134-x
Journal of Neuroinflammation, 18:83, 1-15. BioMed Central
Journal of Neuroinflammation, 18(1):83. BioMed Central
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Journal of Neuroinflammation
Background The biomechanical properties of the brain have increasingly been shown to relate to brain pathology in neurological diseases, including multiple sclerosis (MS). Inflammation and demyelination in MS induce significant changes in brain stiff
Autor:
Micha M. M. Wilhelmus, Osoul Chouchane, Maarten Loos, Cornelis A. M. Jongenelen, John J. P. Brevé, Allert Jonker, John G. J. M. Bol, August B. Smit, Benjamin Drukarch
Publikováno v:
Wilhelmus, M M M, Chouchane, O, Loos, M, Jongenelen, C A M, Brevé, J J P, Jonker, A, Bol, J G J M, Smit, A B & Drukarch, B 2022, ' Absence of tissue transglutaminase reduces amyloid-beta pathology in APP23 mice ', Neuropathology and Applied Neurobiology, vol. 48, no. 4, e12796, pp. 1-13 . https://doi.org/10.1111/nan.12796
Neuropathology and Applied Neurobiology, 48(4):e12796, 1-13. Wiley-Blackwell
Neuropathology and Applied Neurobiology, 48(4):e12796. Wiley-Blackwell
Wilhelmus, M M M, Chouchane, O, Loos, M, Jongenelen, C A M, Brevé, J J P, Jonker, A, Bol, J G J M, Smit, A B & Drukarch, B 2022, ' Absence of tissue transglutaminase reduces amyloid-beta pathology in APP23 mice ', Neuropathology and Applied Neurobiology, vol. 48, no. 4, e12796 . https://doi.org/10.1111/nan.12796
Neuropathology and Applied Neurobiology, 48(4):e12796, 1-13. Wiley-Blackwell
Neuropathology and Applied Neurobiology, 48(4):e12796. Wiley-Blackwell
Wilhelmus, M M M, Chouchane, O, Loos, M, Jongenelen, C A M, Brevé, J J P, Jonker, A, Bol, J G J M, Smit, A B & Drukarch, B 2022, ' Absence of tissue transglutaminase reduces amyloid-beta pathology in APP23 mice ', Neuropathology and Applied Neurobiology, vol. 48, no. 4, e12796 . https://doi.org/10.1111/nan.12796
Aims: Alzheimer's disease (AD) is characterised by amyloid-beta (Aβ) aggregates in the brain. Targeting Aβ aggregates is a major approach for AD therapies, although attempts have had little to no success so far. A novel treatment option is to focus
Autor:
Thecla A. van Wageningen, Emma Gerrits, Nieske Brouwer, John J. P. Brevé, Jeroen J. G. Geurts, Bart J. L. Eggen, H. W. G. M. (Erik) Boddeke, Anne-Marie van Dam
Publikováno v:
Brain Communications, 4(2):005. Oxford University Press
Brain Communications, 4(2):fcac005. Oxford University Press
van Wageningen, T A, Gerrits, E, Brouwer, N, Breve, J J P, Geurts, J J G, Eggen, B J L, Boddeke, H W G M E & van Dam, A-M 2022, ' Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis ', Brain Communications, vol. 4, no. 2, 005 . https://doi.org/10.1093/braincomms/fcac005
van Wageningen, T A, Gerrits, E, Brouwer, N, Breve, J J P, Geurts, J J G, Eggen, B J L, Boddeke, H W G M & van Dam, A-M 2022, ' Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis ', Brain Communications, vol. 4, no. 2, fcac005 . https://doi.org/10.1093/braincomms/fcac005
Brain Communications, 4(2):fcac005. Oxford University Press
van Wageningen, T A, Gerrits, E, Brouwer, N, Breve, J J P, Geurts, J J G, Eggen, B J L, Boddeke, H W G M E & van Dam, A-M 2022, ' Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis ', Brain Communications, vol. 4, no. 2, 005 . https://doi.org/10.1093/braincomms/fcac005
van Wageningen, T A, Gerrits, E, Brouwer, N, Breve, J J P, Geurts, J J G, Eggen, B J L, Boddeke, H W G M & van Dam, A-M 2022, ' Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis ', Brain Communications, vol. 4, no. 2, fcac005 . https://doi.org/10.1093/braincomms/fcac005
van Wageningen et al. present gene expression data of demyelinated and normal-appearing white and grey matter of multiple sclerosis leucocortical lesions. They find that grey matter lesions primarily feature gene expression indicative of a microglial
Autor:
Micha M.M. Wilhelmus, John G.J.M. Bol, Claudia Sestito, John J. P. Brevé, Benjamin Drukarch, Anne Marie van Dam
Publikováno v:
Cytokine, 128:155024. Academic Press Inc.
Sestito, C, Brevé, J J P, Bol, J G J M, Wilhelmus, M M M, Drukarch, B & van Dam, A M 2020, ' Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages ', Cytokine, vol. 128, 155024 . https://doi.org/10.1016/j.cyto.2020.155024
Sestito, C, Brevé, J J P, Bol, J G J M, Wilhelmus, M M M, Drukarch, B & van Dam, A M 2020, ' Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages ', Cytokine, vol. 128, 155024 . https://doi.org/10.1016/j.cyto.2020.155024
Macrophages exert either a detrimental or beneficial role in Multiple Sclerosis (MS) pathology, depending on their inflammatory environment. Tissue Transglutaminase (TG2), a calcium-dependent cross-linking enzyme, has been described as a novel marker
Autor:
Charlotte E. Teunissen, Anne-Marie van Dam, Micha M.M. Wilhelmus, Martijn D. Steenwijk, Claudia Sestito, Cyra E. Leurs, Joep Killestein, Jos W. R. Twisk, John J. P. Brevé, Benjamin Drukarch
Publikováno v:
Neurology(R) neuroimmunology & neuroinflammation, 8(4). Lippincott Williams and Wilkins
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Sestito, C, Leurs, C E, Steenwijk, M D, Brevé, J J P, Twisk, J W R, Wilhelmus, M M M, Drukarch, B, Teunissen, C E, van Dam, A-M & Killestein, J 2021, ' Tissue Transglutaminase Expression Associates With Progression of Multiple Sclerosis ', Neurology(R) neuroimmunology & neuroinflammation, vol. 8, no. 4 . https://doi.org/10.1212/NXI.0000000000000998
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Sestito, C, Leurs, C E, Steenwijk, M D, Brevé, J J P, Twisk, J W R, Wilhelmus, M M M, Drukarch, B, Teunissen, C E, van Dam, A-M & Killestein, J 2021, ' Tissue Transglutaminase Expression Associates With Progression of Multiple Sclerosis ', Neurology(R) neuroimmunology & neuroinflammation, vol. 8, no. 4 . https://doi.org/10.1212/NXI.0000000000000998
ObjectiveThe clinical course of multiple sclerosis (MS) is variable and largely unpredictable pointing to an urgent need for markers to monitor disease activity and progression. Recent evidence revealed that tissue transglutaminase (TG2) is altered i
Autor:
Benjamin Drukarch, Hanneke van Mierlo, John J. P. Brevé, John G.J.M. Bol, Wia Baron, Jenny C. de Jonge, Anne-Marie van Dam, Nathaly Espitia Pinzon
Publikováno v:
Espitia Pinzon, N, van Mierlo, H, de Jonge, J C, Brevé, J J P, Bol, J G J M, Drukarch, B, van Dam, A-M & Baron, W 2019, ' Tissue transglutaminase promotes early differentiation of oligodendrocyte progenitor cells ', Frontiers in Cellular Neuroscience, vol. 13, 281 . https://doi.org/10.3389/fncel.2019.00281
Frontiers in cellular neuroscience, 13:281. Frontiers Media SA
Frontiers in Cellular Neuroscience, 13:281. Frontiers Media S.A.
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in cellular neuroscience, 13:281. Frontiers Media SA
Frontiers in Cellular Neuroscience, 13:281. Frontiers Media S.A.
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Demyelinated lesions of the central nervous system are characteristic for multiple sclerosis (MS). Remyelination is not very effective, particular at later stages of the disease, which results in a chronic neurodegenerative character with worsening o
Autor:
Joep Killestein, Benjamin Drukarch, John J. P. Brevé, Anne-Marie van Dam, Claudia Sestito, Micha M.M. Wilhelmus, Charlotte E. Teunissen
Publikováno v:
Medical Sciences, Vol 6, Iss 4, p 108 (2018)
Medical Sciences
Volume 6
Issue 4
Drugs, 6(4). Adis International Ltd
Sestito, C, Brevé, J J P, Killestein, J, Teunissen, C E, Wilhelmus, M M M, Drukarch, B & van Dam, A-M 2018, ' Differential Expression of Tissue Transglutaminase Splice Variants in Peripheral Blood Mononuclear Cells of Primary Progressive Multiple Sclerosis Patients ', Drugs, vol. 6, no. 4 . https://doi.org/10.3390/medsci6040108
Medical Sciences
Volume 6
Issue 4
Drugs, 6(4). Adis International Ltd
Sestito, C, Brevé, J J P, Killestein, J, Teunissen, C E, Wilhelmus, M M M, Drukarch, B & van Dam, A-M 2018, ' Differential Expression of Tissue Transglutaminase Splice Variants in Peripheral Blood Mononuclear Cells of Primary Progressive Multiple Sclerosis Patients ', Drugs, vol. 6, no. 4 . https://doi.org/10.3390/medsci6040108
Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disorder of the central nervous system (CNS) characterized by inflammation and immune cell infiltration in the brain parenchyma. Tissue transglutaminase (TG2), a calcium-dependent cross