Zobrazeno 1 - 10
of 404
pro vyhledávání: '"John J Mullins"'
Autor:
Josselin Nespoux, Marie-Louise T. Monaghan, Natalie K. Jones, Kevin Stewart, Laura Denby, Alicja Czopek, John J. Mullins, Robert I. Menzies, Andrew H. Baker, Matthew A. Bailey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract P2X7 receptors mediate immune and endothelial cell responses to extracellular ATP. Acute pharmacological blockade increases renal blood flow and filtration rate, suggesting that receptor activation promotes tonic vasoconstriction. P2X7 expre
Externí odkaz:
https://doaj.org/article/3754b0ae722445b28dc0fc7b7de55dfa
Autor:
Cara Brown, Linda J. Mullins, Katrina Wesencraft, Gail McConnell, Mariana Beltran, Neil C. Henderson, Bryan Conway, Scott Hoffmann, Sebastian Rider, John J. Mullins
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss S4, Pp 35-47 (2021)
Externí odkaz:
https://doaj.org/article/dd66e9b66cbd4c1ab25a253672381bc8
Autor:
Jonathan M. Taylor, Carl J. Nelson, Finnius A. Bruton, Aryan Kaveh, Charlotte Buckley, Carl S. Tucker, Adriano G. Rossi, John J. Mullins, Martin A. Denvir
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Imaging heart development is challenging due to constant tissue movement and changing physical landmarks. Here the authors present an algorithm capable of maintaining phase-locked imaging throughout a 24 hour timespan, enabling long term timelapse im
Externí odkaz:
https://doaj.org/article/178169f074c049959cd3251b5dd86533
Autor:
Aryan Kaveh, Finnius A. Bruton, Charlotte Buckley, Magdalena E. M. Oremek, Carl S. Tucker, John J. Mullins, Jonathan M. Taylor, Adriano G. Rossi, Martin A. Denvir
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neutrophils and macrophages are crucial effectors and modulators of repair and regeneration following myocardial infarction, but they cannot be easily observed in vivo in mammalian models. Hence many studies have utilized larval zebrafish injury mode
Externí odkaz:
https://doaj.org/article/cc36592bdbb1414998961f121fe7fa7b
Autor:
Robert I Menzies, Xin Zhao, Linda J Mullins, John J Mullins, Carolynn Cairns, Nicola Wrobel, Donald R Dunbar, Matthew A Bailey, Christopher J Kenyon
Publikováno v:
Endocrine Connections, Vol 6, Iss 7, Pp 446-457 (2017)
Chronic ACTH exposure is associated with adrenal hypertrophy and steroidogenesis. The underlying molecular processes in mice have been analysed by microarray, histological and immunohistochemical techniques. Synacthen infused for 2 weeks markedly inc
Externí odkaz:
https://doaj.org/article/604365f401a94798b5d7a9d9fb79dcb4
Autor:
Robert I. Menzies, John W.R. Booth, John J. Mullins, Matthew A. Bailey, Frederick W.K. Tam, Jill T. Norman, Robert J. Unwin
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 73-83 (2017)
Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be promoted by infiltration of circulating macrophages. Monocyte chemoattractant protein-1 (MCP-1)
Externí odkaz:
https://doaj.org/article/09543f448dd741b5bce76b3c6f64b596
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 12, Pp 1419-1433 (2016)
The rat has classically been the species of choice for pharmacological studies and disease modeling, providing a source of high-quality physiological data on cardiovascular and renal pathophysiology over many decades. Recent developments in genome en
Externí odkaz:
https://doaj.org/article/5e2b82ec40dd485d849c393926b5e345
Autor:
Frances E. Jones, Matthew A. Bailey, Lydia S. Murray, Yinhui Lu, Sarah McNeilly, Ursula Schlötzer-Schrehardt, Rachel Lennon, Yoshikazu Sado, David G. Brownstein, John J. Mullins, Karl E. Kadler, Tom Van Agtmael
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 2, Pp 165-176 (2016)
Collagen IV is a major component of basement membranes, and mutations in COL4A1, which encodes collagen IV alpha chain 1, cause a multisystemic disease encompassing cerebrovascular, eye and kidney defects. However, COL4A1 renal disease remains poorly
Externí odkaz:
https://doaj.org/article/ca3dc48772f04bf2b39a587f4c1bb2ff
Oestrogen and progesterone play essential roles in the release of mature oocytes, the priming and cycling of the uterine lining, and the maintenance of mammalian pregnancy. Progesterone is synthesizedde novoat the embryo implantation site in the mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf76c859a074403637bbdaadf3c64bc
https://doi.org/10.1101/2022.11.03.515013
https://doi.org/10.1101/2022.11.03.515013
Autor:
Jonathan M. Taylor, Carl J. Nelson, Finnius A. Bruton, Aryan Kaveh, Charlotte Buckley, Carl S. Tucker, Adriano G. Rossi, John J. Mullins, Martin A. Denvir
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a8c67e27264340df8c306d453fbabc8b